New HMG-CoA Reductase Inhibitors

HomeNew HMG-CoA Reductase Inhibitors
Catalog No. Product Name Information
E4981 Fluvastatin Fluvastatin is a competitive inhibitor of HMG-CoA reductase with an IC50 value of 40 and 100 nM in human liver microsomes. Fluvastatin also exerts cytoprotective effects against oxidative stress through the Nrf2-dependent antioxidant pathway.
E4792 Atorvastatin calcium hydrate Atorvastatin calcium hydrate (Totalip) is a potent inhibitor of the HMG-CoA reductase . It is used as a potent hypolipidemic agent to reduce the elevated total-cholesterol, low-density lipoprotein (LDL), apolipoprotein B (apo B), and triglyceride (TG) levels, and to increase the high-density lipoprotein cholesterol (HDL-C) level in patients with primary hypercholesterolemia and mixed dyslipidemia.
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