New AMPK Inhibitors

Catalog No.	Product Name	Information
E5944	AMPK-IN-3	AMPK‑IN‑3 (compound 67) is a potent, oxindole‑based, ATP‑site inhibitor of AMP‑activated protein kinase (AMPK), with IC50 of 60.7 nM for AMPKα2, 107 nM for AMPKα1, and 3,820 nM for KDR (VEGFR2). It also effectively suppresses cellular AMPK activity without significantly affecting cell viability or inducing cytotoxicity in chronic myeloid leukemia K562 cells.
E6554	PF-07293893	PF-07293893 is an oral, selective small-molecule activator of the AMPKγ3 (PRKAG3) regulatory subunit and exhibits potential to treat heart failure with preserved ejection fraction (HFpEF).
≡ All AMPK Inhibitors