HomeNew HDAC Inhibitors

New HDAC Inhibitors

Catalog No. Product Name Information
S2190 Pyroxamide (NSC 696085) Pyroxamide (NSC 696085) is a potent, affinity-purified HDAC1 inhibitor with ID50 of 100 nM.
E1554 Tefinostat(CHR-2845) Tefinostat(CHR-2845) is a monocyte/macrophage-targeted inhibitor of pan-histone deacetylase (HDAC). Tefinostat undergoes cleavage mediated by the intracellular esterase human carboxylesterase-1 (hCE-1) to yield the active acid CHR-2847. In vitro studies reveal a specific heightened sensitivity of monocytoid leukemias to tefinostat.
E1469 ITF3756 ITF3756 is a selective histone deacetylase 6 (HDAC6) inhibitor bearing a pentaheterocyclic scaffold. It can be used in research of autoimmune disorders, neurodegenerative diseases, and cancer.
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