Immunology & Inflammation related Chemicals

Cat.No.	Product Name	Information	Product Use Citations
S8141	Cl-amidine	Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. Cl-amidine induces apoptosis.	Immunity, 2025, S1074-7613(25)00069-X Cell Rep, 2025, 44(2):115226 Nat Commun, 2024, 15(1):8663
S2910	Tempol	Tempol (4-Hydroxy-TEMPO) is a superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects. Phase 2.	Autophagy, 2025, 1791-1801 Cell Death Dis, 2024, 15(10):760 Cell Signal, 2023, 108:110712
S1439	Tranilast	Tranilast is an antiallergic drug by inhibiting lipid mediator and cytokine release from inflammatory cells, used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.	EMBO Mol Med, 2025, 17(4):747-774 Virol J, 2025, 22(1):301 PLoS One, 2025, 20(2):e0319381
S5804	N-Acetylcysteine amide (NACA)	N-acetylcysteine amide is a membrane penetrating antioxidant with anti-inflamatory activity through regulation of activation of NF-κB and HIF-1α as well as modulation of ROS.	Pharmacol Res, 2025, 219:107902 iScience, 2025, 28(3):111964 Pharmacol Res Perspect, 2025, 13(3):e70120
S2359	Sinomenine	Sinomenine (Cucoline, Kukoline), a pure alkaloid extracted from the chinese medical plant Sinomenium acutum, is used for the treatment of rheumatism and arthritis.	BMC Pulm Med, 2024, 24(1):229 Sci Rep, 2023, 13(1):3933 Biomed Res Int, 2022, 2022:4914005
S2413	Geniposidic acid	Geniposidic acid is an iridoid glucoside, used to treat inflammation, jaundice and hepatic disorders.	J Pers Med, 2022, 12(2)258 Hum Cell, 2022, 10.1007/s13577-022-00671-y Hum Cell, 2021, 10.1007/s13577-021-00639-4
S7448	CORM-3	CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.	Cell Death Discov, 2024, 10(1):42 Exp Neurol, 2021, 341:113683 Inflammation, 2021, 10.1007/s10753-021-01419-w
S1211	Imiquimod	Imiquimod is a novel synthetic agent with immune response modifying activity.	iScience, 2024, 27(10):110862 Biomaterials, 2023, 302:122319 J Neuroinflammation, 2022, 19(1):315
S5501	Hydrocortisone acetate	Hydrocortisone Acetate (Cortisol 21-acetate) is the synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties.	Reprod Toxicol, 2022, S0890-6238(22)00068-5 Front Cell Dev Biol, 2021, 9:641527 Int J Radiat Biol, 2021, 1-11
S9311	Germacrone	Germacrone, a major activity component found in Curcuma zedoaria oil product, shows anti-inflammatory, antiandrogenic, and antimicrobial activities.	Front Pharmacol, 2022, 13:1033043 Experimental and Therapeutic Medicine, 2022, 456 Exp Ther Med, 2022, 24(1):456
S3614	Lupeol	Lupeol (Clerodol, Monogynol B, Fagarasterol, Farganasterol) is a significant lupane-type triterpene represented in the plant, fungi and animal kingdoms with anticancer, antiprotozoal, chemopreventive and anti-inflammatory properties.	Life Sciences, 2023, 121647 Toxicol Appl Pharmacol, 2023, 478:116699 Toxicology and Applied Pharmacology, 2023, 116699
S5318	Acacetin	Acacetin (Linarigenin, 5,7-dihydroxy-4'-methoxyflavone, 4'-Methoxyapigenin) is a flavonoid compound that has been shown to have anti-cancer, anti-mutagenic, anti-inflammatory and anti-peroxidative effects.	Mediators Inflamm, 2021, 2021:5265444 Biochem Biophys Res Commun, 2021, 583:146-153 Front Pharmacol, 2020, 11:582520
S2338	Oxymatrine	Oxymatrine (Matrine N-oxide) is a quinolizidine alkaloid extracted from the root of Sophora flavescens with anti-inflammatory, antifibrosis, and antitumor effects. This compound inhibits the iNOS expression and TGF-β/Smad pathway. It is used for the treatment of viral hepatitis, cancer, viral myocarditis, gastrointestinal hemorrhage and skin diseases.	Bioengineered, 2022, 13(5):12912-12926 Front Cell Dev Biol, 2021, 9:684007 Clin Transl Oncol, 2020, 10.1007/s12094-020-02464-x
S9430	Tomatidine Hydrochloride	Tomatidine Hydrochloride, a natural steroidal alkaloid, possesses potent antibacterial activity and has anti-inflammatory effects in macrophages.	Viruses, 2021, 13(8)1533 Viruses, 2021, 1533 Vet Res, 2020, 51(1):136
S2383	Gastrodin	Gastrodin (Gastrodine), an anti-inflammatory polyphenol extracted from Chinese natural herbal Gastrodia elata Blume., benefits neurodegenerative diseases.	Phytomedicine, 2024, 135:156229 Cell Death Discov, 2023, 9(1):364 Cell Signal, 2023, 110:110851
S9289	Astragalin	Astragalin (kaempferol-3-glucoside, Kaempferol 3-O-glucoside, Kaempferol 3-D-glucoside), a flavonoid from leaves of persimmon and green tea seeds, has anti-tumor, anti-inflammatory and anti-oxidant activities.	Free Radic Biol Med, 2025, 239:317-335 Free Radical Biology and Medicine, 2025, 317-335 Chem Biol Drug Des, 2021, 10.1111/cbdd.13933
S4761	Thymoquinone	Thymoquinone (TQ) is the bioactive phytochemical constituent of the seeds oil of Nigella sativa with anti-inflammatory and anti-oxidant effects.	Int J Mol Sci, 2022, 23(4)2305 International Journal of Molecular Sciences, 2022, 2305 Chem Biol Interact, 2022, 365:110070
S5686	Tryptanthrin	Tryptanthrin is a natural alkaloidal compound having basic indoloquinazoline moiety. It has broad spectrum of biological activities including anticancer activity, anti-inflammatory, antiprotozoal, antiallergic, antioxidant, and antimicrobial.	J Org Chem, 2025, 90(29):10434-10441 Redox Biol, 2024, 76:103323 BMC Complement Med Ther, 2024, 24(1):28
S5500	Amodiaquine hydrochloride	Amodiaquine Hydrochloride is the hydrochloride salt of amodiaquine, an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties.	Nat Biomed Eng, 2021, 10.1038/s41551-021-00718-9 bioRxiv, 2020, 10.1101/2020.04.13.039917 bioRxiv, 2020, 2020/9/20.4.7.30734
S5457	Curculigoside	Curculigoside (Curculigoside A), a diterpenoid triepoxide, is one of the main bioactive phenolic compounds isolated from the rhizome of Curculigo orchioides Gaertn. and has potent antioxidant, anti-osteoporotic, immunomodulatory, and neuroprotective effects.	Antioxidants (Basel), 2024, 13(4)420 Antioxidants, 2024, 420 Life Sciences, 2020, 118356
S9290	Linarin	Linarin (Acaciin, Buddleoside, Acacetin-7-O-rutinoside), a natural flavonoid cpompound, has pharmacological effects, including anti-inflammatory, neuro-protective, cardioprotective and antioxidative effects.	Journal of Chemical Information and Modeling, 2021, 6094-6106 Frontiers in Pharmacology, 2020, 582520 Front Pharmacol, 2020, 11:582520
S4170	Coumarin	Coumarin is a secondary phytochemical with hepatotoxic and carcinogenic properties.	J Immunother Cancer, 2024, 12(11)e009805 Biosci Rep, 2021, BSR20211828 Dissertation, Christian-Albrechts-Universität zu Kiel, 2018, 139
S9038	Calycosin	Calycosin (3'-Hydroxyformononetin), an isoflavonoid, is the major active component in Radix Astragali. It shows antitumor, anti-inflammatory, neuroprotective and pro-angiogenesis effects.	Immun Inflamm Dis, 2023, 10.1002/iid3.935 Immunity, Inflammation and Disease, 2023, e935 Pharmacol Res, 2022, 185:106489
S3027	Fenoprofen calcium hydrate	Fenoprofen calcium hydrate(Fenoprofen calcium salt dihydrate,Feprona dihydrate,Progesic dihydrate) is a non-steroidal anti-inflammatory drug (NSAID).	Communications Medicine, 2025, 420 Genome Medicine, 2021, 168 Genome Med, 2021, 13(1):168
S3881	Scopoletin	Scopoletin (Esculetin 6-methyl ether, Gelseminic acid, 6-Methylesculetin, Chrysatropic acid) is the main bioactive constituent of flower buds from Magnolia fargesii with anti-inflammatory, hypouricemic, and antioxidant activities.	Biochemistry and Biophysics Reports, 2025, 102021 Biochem Biophys Rep, 2025, 42:102021 International Immunopharmacology, 2022, 108382
S4706	Eugenol	Eugenol (4-Allyl-2-methoxyphenol, 4-Allylguaiacol, Eugenic acid, Allylguaiacol) is a naturally occuring scent chemical found in clove oil and other plants. The physiologic effect of this compound is by means of increased Histamine Release, and cell-mediated Immunity.	Hepatol Commun, 2024, 8(3)e0396 Redox Biology, 2020, 101619 Redox Biol, 2020, 36:101619
S6439	Talniflumate	Talniflumate (MSI-1995) is an anti-inflammatory molecule studied and used as a mucin regulator in the treatment of cystic fibrosis, chronic obstructive pulmonary disease (COPD) and asthma. This compound is also an inhibitor of human calcium-activated chloride channels.	Toxicol Lett, 2025, 406:31-37 Acta Pharmaceutica Sinica B, 2023, 662-677 Acta Pharm Sin B, 2023, 13(2):662-677
S4690	Escin	Escin (Aescin) is a mixture of saponins with anti-inflammatory, vasoconstrictor and vasoprotective effects found in Aesculus hippocastanum(the horse chestnut).	Adv Sci (Weinh), 2025, 12(32):e01956 Frontiers in Pharmacology, 2023, 1086429 European Journal of Pharmacology, 2023, 175951
S9131	Punicalagin	Punicalagin, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects., This compound, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects.	SLAS Discov, 2024, S2472-5552(24)00007-8 Cell, 2020, 30;181(3):637-652.e15. Cell, 2020, 30;181(3):637-652e15
S9502	Madecassic acid	Madecassic acid (Brahmic acid), a natural triterpene first isolated from C. asiatica, has diverse anti-inflammatory and anti-diabetic effects, blocking NF-κB activation in macrophages and causing by iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 inhibition.	Frontiers in Microbiology, 2024, 1392178 Drug Design, Development and Therapy, 2022, 3793-3804 Drug Des Devel Ther, 2022, 16:3793-3804
S5517	Fenamic acid	Fenamic acid (N-Phenylanthranilic acid, 2-(Phenylamino)benzoic acid, 2-Anilinobenzoic acid, Diphenylamine-2-carboxylic acid) serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), including mefenamic acid, tolfenamic acid, flufenamic acid, and meclofenamic acid.	Mol Pain, 2024, 20:17448069241295987 Antiviral Res, 2023, 216:105674 J Biol Chem, 2019, 294(45):16908-16917
S9183	Ruscogenin	Ruscogenin, a major steroidal sapogenin of traditional Chinese herb Radix Ophiopogon japonicus, has been reported to exert significant anti-inflammatory and anti-thrombotic activities.	Dig Dis Sci, 2025, 10.1007/s10620-025-09412-1 Digestive Diseases and Sciences, 2025, nan International Journal of Molecular Sciences, 2016, 1418
S1823	Fenoprofen Calcium	Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.	Communications Medicine, 2025, 420 Genome Med, 2021, 13(1):168
S5674	Lodoxamide Tromethamine	Lodoxamide Tromethamine (Alomide, Lodoxamidetromethamine) is the tromethamide salt form of lodoxamide, a synthetic mast cell stabilizing compound with anti-inflammatory activity.	Experimental Eye Research, 2022, 109065 Exp Eye Res, 2022, 219:109065
S9213	Jujuboside A	Jujuboside A, isolated from Semen Ziziphi Spinosae, exerts anti-oxidant, anti-inflammatory activities, and reduces the cell apoptosis.	Cancer Medicine, 2023, 1616-1629 Cancer Med, 2022, 10.1002/cam4.4977
S3956	Tetramethylpyrazine	Tetramethylpyrazine (ligustrazine, TMP) is a natural compound isolated from Chinese herbal medicine Ligusticum wallichii (Chuan Xiong) with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.	Front Pharmacol, 2025, 16:1571552 Biomed Pharmacother, 2022, 150:113010
S9043	6-Shogaol	6-Shogaol, a naturally occuring product found in ginger, has anti-inflammatory and anticancer properties.,	Biomolecules, 2020, 10(10)E1380 Biomolecules, 2020, 1380
S3824	Quercitrin	Quercitrin (3-rhamnosyl quercetin, Sophoretin, Meletin, Xanthaurine), a glycoside of quercetin, has been found as a main bioactive constituent in T. sinensis leaves and has antioxidant, anti-inflammatory, and anti-allergic activities.	J Biol Chem, 2023, 299(6):104789 Molecules, 2023, 28(3)1444
S6185	Arachidonic acid	Arachidonic acid (Arachidonate) is an unsaturated, essential fatty acid found in animal and human fat as well as in the liver, brain, and glandular organs. It is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.,	Cell Commun Signal, 2025, 23(1):352 Bone Res, 2022, 10(1):20
S9304	Platycodin D	Platycodin D, the main saponin isolated from Chinese herb Platycodonis Radix, exhibits anti-inflammatory, anti-allergic, cholesterol-lowering and neuroprotective properties.	Molecules, 2024, 29(22)5275 Sci Rep, 2016, 6:37997
S4188	Sasapyrine	Sasapyrine (Salsalate, NSC-49171) is a nonsteroidal oral anti-inflammatory agent.	Sci Rep, 2025, 15(1):12720 Scientific Reports, 2025, 15(1)
S6322	Pipecolic acid	Pipecolic acid (piperidine-2-carboxylic acid), a metabolite of lysine found in human physiological fluids such as urine, plasma and CSF, is an important regulator of immunity in plants and humans alike.	Pharmaceuticals (Basel), 2023, 16(7)1051 Pharmaceuticals, 2023, 1051
S5648	Iguratimod	Iguratimod (T-614) is a small molecule compound with anti-inflammatory and immunomodulatory actions and used for the treatment of rheumatoid arthritis.	Front Pharmacol, 2022, 13:865363 Front Microbiol, 2019, 10:2225
S9035	Isovitexin	Isovitexin (saponaretin, Apigenin-6-C-glucoside), an active component of many traditional Chinese medicines, has various activities, such as anti-oxidant, anti-inflammatory, anti-alzheimer disease (AD) effects and so on.	Frontiers in Pharmacology, 2020, 582520 Front Pharmacol, 2020, 11:582520
S9074	Buddlejasaponin IVb	Buddlejasaponin IVb (Saikosaponin 1b), a major component of Pleurospermum kamtschaticum, exerts anti-inflammatory and cytotoxic effects against cancer cells.	Vet Microbiol, 2022, 272:109516 Veterinary Microbiology, 2022, 109516
S3877	Lysionotin	Lysionotin is a natural flavonoid predominantly found in fewflower lysionotus herbs and possesses many pharmacological properties, such as antibacterial, anti-inflammatory, antihypertensive, and free radical scavenging activities.	Sci Rep, 2025, 15(1):31306 Front Oncol, 2021, 11:674492
S9411	Liensinine	Liensinine, an important functional compound in lotus seeds, has anti-cancer, anti-fibrosis, anti-proliferative, antioxidant, and anti-inflammatory activities.	J Cosmet Dermatol, 2024, 10.1111/jocd.16587 Cell Death Dis, 2022, 13(11):1000
S9105	Ginsenoside CK	Ginsenoside CK is a ginsenoside found in Panax species and has a role as a plant metabolite, an antineoplastic agent, a hepatoprotective agent, an anti-allergic agent and an anti-inflammatory agent.	Journal of Ginseng Research, 2023, 274-282 J Ginseng Res, 2023, 47(2):274-282
S9437	Echinatin	Echinatin is a licorice extract that displays antioxidant properties and anti-inflammatory activities.	Biomed Pharmacother, 2024, 179:117359 Biomedicine & Pharmacotherapy, 2024, 117359
S9120	Scutellarein	Scutellarein (6-Hydroxyapigenin), extracted from the perennial herb Scutellaria lateriflora, has antioxidant, antitumor, anti-adipogenic, antiviral and anti-inflammatory activities	J Adv Res, 2025, S2090-1232(25)00499-0 SLAS Discov, 2024, S2472-5552(24)00007-8
S3813	Bakuchiol	Bakuchiol ((S)-(+)-Bakuchiol) is a meroterpene phenol abundant in seeds and leaves of the plant Psoralea corylifolia. It has anti-inflammatory and antimicrobial activities., This compound is a meroterpene phenol abundant in seeds and leaves of the plant Psoralea corylifolia. It has anti-inflammatory and antimicrobial activities.	Cell Prolif, 2019, 52(5):e12666 Cell Proliferation, 2019, e12666
S9136	Neochlorogenic acid	Neochlorogenic acid (Neochlorogenate, 5-O-Caffeoylquinic acid) is a natural polyphenolic compound found in some types of dried fruits and a variety of other plant sources such as peaches. It shows antioxidant, antibacterial, antiviral, and antipyretic activities and exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia.	Biomacromolecules, 2024, 25(2):729-740 Biomacromolecules, 2024, 729-740
S9474	Acetylharpagide	Acetylharpagide is a monomeric compound extracted from Ajuga decumbens, widely used for remedying infectious and inflammatory diseases.	Molecules, 2020, 25(23)5523 Molecules, 2020, 25(23)E5523
S9264	Decursin	Decursin is a pyranocoumarin obtained from the roots of Angelica gigas Nakai that exhibits anti-cancer, anti-inflammatory and neuroprotective activities.	Toxicol Lett, 2025, 406:31-37 Int J Mol Sci, 2024, 25(18)9939
S6476	Eicosapentaenoic Acid (EPA)	Eicosapentaenoic acid (EPA) is an omega-3 polyunsaturated fatty acid with antiinflammatory properties, and is present in fish and fish oils, including salmon, cod, and krill oils.	Int Immunopharmacol, 2023, 10.1016/j.intimp.2023.111181 Int Immunopharmacol, 2023, 125(Pt B):111181
S3062	Diclofenac Potassium	Diclofenac potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.	Pharm Res, 2022, 39(10):2515-2527
S2411	Geniposide	Geniposide is an iridoid glycoside isolated from the fruit of Gardenia jasminoides Ellis.	Phytomedicine, 2023, 117:154918
S5737	Diclofenac Epolamine	Diclofenac Epolamine (DHEP, DIEP, diclofenac hydroxyethylpyrrolidine) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions.	Pharm Res, 2022, 39(10):2515-2527
S5157	Thymol	Thymol (2-isopropyl-5-methylphenol, IPMP), a naturally occurring monocyclic phenolic compound derived from Thymus vulgaris (Lamiaceae), has been reported to exhibit anti-inflammatory property in vivo and vitro.	J Microbiol Biotechnol, 2023, 33(1):43-50
S9203	Notopterol	Notopterol is a kind of furanocoumarin that possesses anti-inflammatory, analgesic, and anticancer activities.	Heliyon, 2024, 10(6):e28094
E2634	H-Leu-Leu-OMe Hydrochloride	H-Leu-Leu-OMe Hydrochloride (H-LEU-LEU-OME HCL, L-Leucyl-L-Leucine methyl ester), a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential, also can induce endolysosomal pathway stress.	INTERNATIONAL DOCTORAL SCHOOL OF THE USC, 2023,
S9247	Isoliensinine	Isoliensinine is an alkaloid produced by the edible plant Nelumbo nucifera. It possesses anti-cancer, anti-fibrosis, anti-proliferative, antioxidant, and anti-inflammatory activities.	Cell Death Dis, 2022, 13(11):1000
S9281	Peimine	Peimine (Verticine, Wanpeinine A) is a major biologically active component of Fritillaria ussuriensis, exhibits anti-inflammatory and pain suppression properties at the cellular level.	Chem Biol Interact, 2025, 405:111312
S9293	Isoliquiritin	Isoliquiritin (Neoisoliquritin) is a flavonoid glycoside compound from licorice possessing a broad spectrum of pharmacological activities including antioxidant, anti-inflammatory, and anti-depression activities.	Front Med (Lausanne), 2022, 9:873739
S6243	Ethyl pyruvate	Ethyl pyruvate (CTI-01) is a simple aliphatic ester of pyruvic acid and has been shown to have robust neuroprotective effects via its anti-inflammatory, anti-oxidative, and anti-apoptotic functions.	BMC Gastroenterol, 2024, 24(1):245
S9309	Micheliolide	Micheliolide, a sesquiterpene lactone isolated from Michelia compressa and Michelia champaca, inhibits various inflammatory response and may serve as a neuroprotective agent in neuroinflammation-related neurodegenerative disorders.	Biomed Res, 2025, 46(5):225-232
S9019	Quillaic acid	Quillaic acid is the major aglycone of the widely studied saponins of the Chilean indigenous tree Quillaja saponaria Mol and shows strong anti-inflammatory activity.	Bioorg Med Chem, 2025, 132:118478
S3675	Umbelliferone	Umbelliferone (7-hydroxycoumarin, hydrangine, skimmetine, beta-umbelliferone) is a 7-hydroxycoumarin that is a pharmacologically active agent. It is a fluorescing compound used as a sunscreen agent and shows good inhibitions of DPPH, hydroxyl, superoxide anion and ABTS radicals with anti-inflammatory, anti-hyperglycaemic, molluscicidal and anti-tumor activities.	Food Chem Toxicol, 2022, S0278-6915(22)00089-8
S3932	Astilbin	Astilbin (Isoastilbin, Neoastilbin, Neoisoastilbin, Taxifolin 3-O-rhamnoside), a flavonoid compound isolated from the rhizome of Smilax glabra Roxb, displays anticancer, antioxidative, anti-inflammatory, and immunosuppressive activities.	PLoS One, 2024, 19(7):e0306543
S9057	Sinigrin	Sinigrin (Allylglucosinolate, 2-Propenylglucosinolate) is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects.	J Invest Dermatol, 2018, 138(12):2644-2652
S9061	Hydroxy safflor yellow A	Hydroxy safflor yellow A, a monomer extracted from Carthamus tinctorius L., possesses various kinds of bio-activities, including anti-oxidation, anti-inflammatory actions, anti-platelet aggregation, anti-tumor and anti-myocardial injury effects.	World J Emerg Med, 2024, 15(3):206-213
S9417	Homoplantaginin	Homoplantaginin (Hispidulin-7-glucoside), a main flavonoid from a traditional Chinese medicine Salvia plebeia, has anti-inflammatory and anti-oxidant properties. This compound inhibits TNF-α and IL-6 mRNA expression, IKKβ and NF-κB phosphorylation.	Front Pharmacol, 2025, 16:1526107
S9427	Tabersonine	Tabersonine is a terpene indole alkaloid found in the medicinal plant Catharanthus roseus and shows hypotensive activity, anti-tumor activity, hypoglycemic, diuretic activity.	Pharm Biol, 2024, 62(1):394-403
S9115	Wogonoside	Wogonoside (Oroxindin, Wogonin 7-O-glucuronide, Glychionide B), the main flavonoid component derived from the root of Scutellaria baicalensis Georgi, displays anti-inflammatory, anti-angiogenic, and anticancer chemotherapeutic activities.	FASEB J, 2021, 35(9):e21870
S9127	Carnosol	Carnosol is a naturally occurring phenolic diterpene found in rosemary. It has anti-oxidant, anti-inflammatory and anti-cancer activities.	ACS Sustain Chem Eng, 2023, 11(12):4727-4737
S9146	Anwuligan	Anwuligan (Macelignan), a natural compound isolated from Myristica fragrans Houtt, has antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species. It also shows antioxidant, free radical scavenging, and neuroprotective activities.	Front Nutr, 2022, 9:892558
S5869	Cortisone	Cortisone is a pregnane steroid hormone and one of main substance released by the body as a reaction to stress. It suppresses the immune system, thus reducing inflammation and attendant pain and swelling at the site of the injury.	Drug Test Anal, 2020, 10.1002/dta.2917
S3928	Baccatin Ⅲ	Baccatin Ⅲ is a polycyclic diterpene which can be used for the semi-synthesis of paclitaxel and analogs. It exhibits immunomodulatory and anticancer chemotherapeutic activities.	Front Chem, 2024, 12:1437141
S1939	Levamisole hydrochloride	Levamisole, also known as (-)-Tetramisole, is an inhibitor of alkaline phosphatase, used as an anthelmintic.
S1679	Flurbiprofen	Flurbiprofen (a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs)) is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs).
S4098	Halcinonide	Halcinonide(SQ-18566) is a high potency corticosteroid used in topical preparations as an anti-inflammatory agent.
S5459	Aucubin	Aucubin (Rhinanthin), an iridoid glycoside existing in medicinal plants, has been reported to show an anti-inflammatory activity by suppression of TNF-α production in murine macrophages.
E0215	Isorhapontigenin	Isorhapontigenin (ISOR), isolated from Belamcanda chinensis, is a derivative of stilbene. This compound possessed potent antioxidative activity. It suppresses interleukin-1β-induced inflammation and cartilage matrix damage in rat chondrocytes.
E3524	Oregano Extract	Oregano Extract is extracted from Origanum vulgare, which has benefits for cardiovascular protection, cancer prevention, and lowers gastrointestinal inflammation.
S3982	Batyl alcohol	Batyl alcohol (Batilol, Stearyl monoglyceride, 1-O-Octadecylglycerol, Batilolum), isolated from shark liver oil, is also present in yellow bone marrow of animals and has been described as an inflammatory agent.
S5471	Monotropein	Monotropein, an iridoids glycoside isolated from the roots of Morinda officinalis How, has been demonstrated to exhibit anti-inflammatory activity.
E0216	Hinokiflavone	Hinokiflavone, isolated from Selaginella P. Beauv, Juniperus phoenicea and Rhus succedanea, possesses excellent pharmacological activities, including anti-inflammatory, antioxidant and antitumor activity. This compound induces apoptosis and inhibits migration of breast cancer cells via EMT signalling pathway.
S5871	Trans-Tranilast	Trans-Tranilast is an antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.
S5458	Verbascoside	Verbascoside (Acteoside, Kusaginin), a phenylpropanoid glycoside from lemon verbena, has several biological properties such as anti-inflammatory, antimicrobial, antitumor, and antioxidant.
S3997	Oxaceprol	Oxaceprol (N-acetyl-L-hydroxyproline) is an anti-inflammatory drug used in the treatment of osteoarthritis.
E3818	Solidago Decurrens Extract	Solidago Decurrens Extract is extracted from Solidago decurrens, which is used medicinally for promoting hemostasis and treating a variety of conditions, including snakebites, carbuncles, and furuncles.
S6249	Picolinic acid (PCL 016)	Picolinic acid (PCL 016) is a pyridine carboxylate metabolite of tryptophan and acts as an anti-infective and immunomodulator. It acts by binding with the zinc associated with zinc finger proteins to alter their structure and inhibit function.
S5322	Sodium gualenate	Sodium gualenate (Guaiazulenesulfonate sodium), a hydrophilic derivative of guaiazulene (GA), is an unstable compound, which is gradually decomposed in the solid state at room temperature. It has anti-inflammatory and wound-healing effects.
S9204	Oroxylin A	Oroxylin A (6-Methoxybaicalein) is a flavonoid isolated from Scutellaria root that exhibits multiple pharmacological activities, including anti-oxidative, anti-inflammatory, anti-viral and anti-tumor properties.
E3139	Angelica Sinensis Extract	Angelica Sinensis Extract is extracted from the dried root of Angelica Sinensis (Radix Angelica Sinensis), of which the effects on cerebral infarction are through multiple pathways, including anti-arthrosclerosis, improving microcirculation, anti-platelet aggregation, anti-inflammatory and anti-oxidative effects.
E7230	7β-Hydroxycholesterol	7β-Hydroxycholesterol is an oxysterol derived from the oxidation of cholesterol. It induces endothelial apoptosis, IL-1β secretion, and oxidative stress, leading to inflammation and organelle dysfunction. It also upregulates ICAM-1, VCAM-1, and E-selectin, thereby enhancing leukocyte adhesion in early atherosclerosis.
E7023	Phosphorylcholine chloride	Phosphorylcholine chloride (Phosphocholine chloride) is a zwitterionic small molecule that forms the hydrophilic head group of major eukaryotic membrane phospholipids and is also found on the surface of commensal or pathogenic bacteria associated with eukaryotes. It exhibits immunomodulatory properties and commonly used in biomaterial coatings to reduce protein adsorption, prevent unwanted cell adhesion, and improve implant biocompatibility.
S9216	Esculentoside A	Esculentoside A, isolated from the Chinese herb phytolacca esculenta, possesses a broad inhibitory effect on a panel of pro-inflammation molecules with less toxicity.
S9222	Dipotassium glycyrrhizinate	Glycyrrhizinate dipotassium (Neubormitin) is a widely used anti-inflammatory agent isolated from the licorice root.
E3846	Semen Pruni Extract	Semen Pruni Extract is extracted from Semen pruni, which is used for oedema, dermatophytosis, hypertension, constipation, chronic tracheitis, and other conditions.
E3557	Radix Peucedani Extract	Radix Peucedani Extract is derived from Peucedani radix (Qianhu), which has strong anti-inflammatory properties and has been an important agent for treating respiratory symptoms and diseases through the centuries.
S0940^New	Edpetiline	Edpetiline is a steroidal alkaloid derived from Fritillaria species that exhibits potent anti-inflammatory and antioxidant effects. It suppresses proinflammatory mediators and reactive oxygen species (ROS) production while inhibiting NF-κB nuclear translocation and selectively blocking p38 and ERK MAPK phosphorylation.
S9228	Schisandrin C	Schisandrin C, a dibenzocyclooctadiene lignan isolated from the fruits of Schisandra chinensis (Turcz.) Baill, has many characteristics including anti-inflammation, anti-tumor, and anti-oxidation.
S9071	Nootkatone	Nootkatone, a natural ingredient that occurs in grapefruit and certain other plants, has antioxidant and anti-inflammatory effects.
S3969	Veratric acid	Veratric acid (3,4-Dimethoxybenzoic acid), a simple benzoic acid derived from plants and fruits, has anti-oxidant, anti-inflammation, and blood pressure-lowering effects. This compound reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation.
E3080	Platycladi Cacumen Extract	Platycladi Cacumen Extract is extracted from Platycladi Cacumen, which has been traditionally used to resist alopecia and promote hair growth.
S9225	Santalol	Santalol is a naturally occuring sesquiterpene that has antibacterial, anti-hyperglycaemic, anti inflammatory and antioxidant effects.
S9237	Berberrubine	Berberrubine (Beroline, 9-Berberoline), an isoquinoline alkaloid isolated from many medicinal plants, possesses diverse pharmacological activities, including glucose-lowering, lipid-lowering, anti-inflammatory, and anti-tumor effects.
S9240	Isofraxidin	Isofraxidin (6,8-Dimethoxyumbelliferone), a bioactive coumarin compound isolated from the functional foods Siberian ginseng and Apium graveolens, is an anti-bacterial, anti-oxidant, and anti-inflammatory agent.
S9242	Narirutin	Narirutin (Naringenin-7-O-rutinoside, Isonaringin), a flavanone abundant in citrus fruits, possesses anti-inflammatory and anti-oxidative effects.
S9243	Protosappanin B	Protosappanin B (FT-0689654, Q-100961), extracted from Lignum Sappan, possesses anti-inflammation and anti-oxidation properties.
S9245	Phellodendrine chloride	Phellodendrine chloride, isolated from the Phellodrndron amurensis, exhibits immunosuppressive and anti-inflammatory activities.
S9246	Tiliroside	Tiliroside, a glycosidic flavonoid, possesses anti-inflammatory, antioxidant, anticarcinogenic and hepatoprotective activities.
E0174	Betamethasone sodium phosphate	Betamethasone sodium phosphate (Betamethasone 21-Phosphate Disodium Salt) is a potent glucocorticoid with anti-inflammatory activity.
E3870	Gardenia Fruit Extract	Gardenia fruit Extract is extracted from the fruits of Gardenia jasminoides Ellis., a flowering plant belonging to Rubiaceae family. Gardenia fruit is used not only as a food coloring but also as a medicine to treat hepatic disorders, headache, jaundice, inflammation, and hypertension.
S9248	Homoorientin	Homoorientin (Isoorientin, Luteolin-6-C-glucoside) is a flavone that acts as a radical scavenger and an antineoplastic agent.
S9005	Stearyl Glycyrrhetinate	Stearyl glycyrrhetinate, the stearyl ester of 18-β-glycyrrhetinic acid, has been demonstrated to improve antiviral effects, reduce inflammation and suppress allergies in the pharmaceutical and cosmetic industry.
S9254	Skimmin	Skimmin is one of the major pharmacologically active molecules present in Hydrangea paniculata, a medical herb used in the traditional Chinese medicine as an anti-inflammatory agent.
S6058	β-Caryophyllene	β-Caryophyllene is a natural bicyclic sesquiterpene that is a constituent of many essential oils. It acts as a non-steroidal anti-inflammatory drug, a fragrance and a metabolite.
E3883	Umbellate Pore Fungus Extract	Umbellate Pore Fungus Extract is extracted from Umbellate pore fungus, which helps in clearing dampness and promoting diuresis.
S5138	Citral	Citral (Geranialdehyde) is an α,β-unsaturated aldehyde present in the oils of several plants. It is an aroma compound used in perfumery for its citrus effect and is also used as a flavor and for fortifying lemon oil.
S9266	Ginsenoside Rc	Ginsenoside Rc, isolated from Panax ginseng, may exert various activities including anti-cancer, anti-inflammatory, antiobesity, and anti-diabetic effects.
E3109	Cymbidium Extract	Cymbidium Extract is extracted from Cymbidium, which has analgesic and anti-inflammatory activities.
E3111	Tribulus Terrestris Extract	Tribulus Terrestris Extract is extracted from Tribulus Terrestris, which has anti-inflammatory, analgesic, antispasmodic, anticancer, antibacterial, anthelmintic, larvicidal, and anticariogenic activities.
S3837	Echinocystic acid	Echinocystic acid (EA), a natural triterpone enriched in various herbs, displays a range of pharmacological activities including anti-inflammatory and antioxidant effects.
S9272	Koumine	Koumine, a Gelsemium alkaloid, possesses analgesic, anti-inflammatory and neurosteroid modulating activities.
E3243	Pinus Pinaster Bark Extract	Pinus Pinaster Bark Extract is extrcated from the bark of Pinus Pinaster, which has anti-inflammatory actions.
S6136	(±)-α-Bisabolol	α-bisabolol is a small, plant-derived, oily sesquiterpene alcohol with some anti-inflammatory and even anti-microbial properties.
S3841	Eleutheroside B	Eleutheroside B (syringin, Syringoside, Lilacin) is a phenylpropanoid glycoside first isolated from A. senticosus and has neuroprotective, tonic, adaptogenic, and immune-modulating properties.
E3603	Ramulus Mori Extract	Ramulus Mori Extract is extracted from Ramulus mori (Mulberry twigs), the dry branch of Morus alba L.. Ramulus Mori is a traditional medicine widely used for diabetes treatment. The major active components of Ramulus Mori are mulberroside A, oxyresveratrol, resveratrol, 4-hydroxycinnamic acid, 7-hydroxycoumarin, and morin, and the components have been demonstrated to possess anti-cancer, anti-hypertensive, anti-diabetic, and anti-inflammatory properties.
E3899	Echinacea Extract (flower)	Extracted from purple coneflower, the flower of Echinacea purpurea, Echinacea angustifolia or Echinacea pallida, this compound is used as a treatment for respiratory tract infections and inflammatory conditions, including common cold, coughs, bronchitis, and inflammation of mouth and pharynx.
S9280	Demethoxycurcumin	Demethoxycurcumin, a natural demethoxy derivative of curcumin, has anti-oxidant, anti-inflammatory, anti-cancer, and anti-angiogenesis properties.
E3254	Terminalia Chebula Extract	Terminalia Chebula Extract is extracted from Terminalia Chebula, which has antioxidant, hepatoprotective, neuroprotective, cytotoxic, antidiabetic, and anti-inflammatory activities.
E6077^New	Hydrocortisone cypionate	Hydrocortisone cypionate is a synthetic corticosteroid and an ester form of hydrocortisone used primarily for treating inflammation and corticosteroid-responsive dermatoses.
E3609	Elaeagnus angustifolia Extract	Elaeagnus angustifolia Extract is extracted from the fruits of Elaeagnus angustifolia L.. Elaeagnus angustifolia fruit extract has acute and chronic anti-inflammatory activities.
E3610	Amomum villosum Extract	Amomum Villosum Extract is extracted from Amomum villosum Lour., a herbaceous plant in the ginger family. Amomum villosum has been proven to be effective in treating gastrointestinal diseases. Treatment with Amomum villosum water extract significantly attenuates intestinal inflammation in inflammatory bowel disease (IBD) rats.
E3257	Polygoni Multiflori Root Extract	Polygoni Multiflori Root Extract is extrcated from the roots of Polygoni Multiflori, which is used for treating tuberculosis that has spread to the lymph nodes, cancer, inflammation of the prostate (prostatitis), and constipation.
E0025	2-Hydroxybenzylamine	2-Hydroxybenzylamine (2-(Aminomethyl)phenol, 2-HOBA, NSC 127870) is a naturally occurring compound found in buckwheat and is a selective scavenger of dicarbonyl electrophiles that protects proteins and lipids from being modified by these electrophiles. 2-HOBA reduces inflammation and plaque apoptotic cells and promotes efferocytosis and features of stable plaques. 2-HOBA has potential for use as a nutrition supplement due to its ability to protect against the damaging effects of oxidative stress.
S9287	Genkwanin	Genkwanin (Apigenin 7-methyl ether) is one of the major non-glycosylated flavonoids in herbs. It has a variety of pharmacological effects including anti-inflammatory, anti-bacterial, antiplasmodial, radical scavenging, chemopreventive and inhibiting 17β-Hydroxysteroid dehydrogenase type 1 activities.
E3613	Sophora tonkinensis Extract	Sophora Tonkinensis Extract is extracted from the dried root ofSophora tonkinensis Gapnep.. Sophora tonkinensis is used in the treatment of pharyngeal and laryngeal diseases. Sophora tonkinensis has hepatoprotective, immunomodulatory, and anticancer effects and produces obvious toxicity to the liver and nervous and cardiovascular systems.
S9288	Casticin	Casticin (Vitexicarpin), as the major active substance in Lithospermum erythrorhyzon, had been reported to mediate multiple pharmacological activities such as antioxidation, antiviral, cardiovascular protection, antineoplastic and anti-inflammation.
E3614	Arnica montana Extract	Arnica Montana Extract is extracted from the flowers of Arnica montana L. (Asteraceae). Arnica montana possesses anti-inflammatory, immune-modulatory, anti-sclerotic, analgesic, antifungal, antioxidant, antibacterial, and anticancer bioactivities.
E3261	Juglandis Semen Extract	Juglandis Semen Extract is extrcetd from the Juglandis Semen, which is commenly used in Knee osteoarthritis treatment.
E3206	Spirodelae Herba Extract	Spirodelae Herba Extract is extracted from Spirodelae, which may be an effective therapeutic agent for the treatment of atopic dermatitis.
E3727	Daphne genkwa Sieb.et Zucc. Extract	Daphne Genkwa Sieb.Et Zucc. Extract is derived from the dried flowers of Daphne genkwa Sieb. et Zucc. (Thymelaeaceae), which are a Chinese herbal medicine used as an abortifacient with purgative, diuretic and anti-inflammatory activities.
S6551	Adelmidrol	Adelmidrol is an analogue of palmitoylethanolamide (PEA) with anti-inflammatory activities.
E3264	Black Bone Rattan extract	Black Bone Rattan Extract is extracted from Gardneria angustifolia, which has the effects of dispelling rheumatism, clearing the meridians and promoting blood circulation.
E3619	Lonicerae Flos Extract	Lonicerae Flos Extract is extracted from Lonicerae flos, the flower bud of Lonicera macranthoides Hand.-Mazz., Lonicera hypoglauca Miq., Lonicera confusa DC., or Lonicera fulvotomentosa Hsu et S. C. Cheng. Lonicerae flos is a traditional Chinese medicine used in the treatment of inflammatory and infectious diseases. Lonicerae flos extract increases survival rates of cecal ligation and puncture (CLP)-induced septic rats.
S4165	Benzydamine HCl	Benzydamine HCl (AF864) is a topical nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, antipyretic and local anesthetic activity.
E3620	Corni Fructus Extract	Corni Fructus Extract is extracted from the fruits of Fructus Corni (Cornus officinalis Sieb. et Zucc.). Fructus Corni is a traditional Chinese herbal medicine that possesses pharmacological actions against inflammation, diabetic nephropathy, tumors, oxidation and aging.
E3316	Scutellariae rhizome Extract	Scutellariae Rhizome Extract is isolated from the rhizome of Scutellaria baicalensis, which contains baicalin as a main constituent, has long been used in China, Japan, and Korea as a traditional medicine and functional food for inflammation, fever, hepatitis, allergic disease, hypertension, etc.
S9296	Fraxin	Fraxin (Fraxetin-8-O-glucoside), a main active component isolated from Cortex Fraxini, possesses a variety of bioactivities such as anti-inflammatory, antioxidant, analgesic, antimicrobial, antiviral, immunomodulatory, anti-hyperuricemia and diuresis.
S9297	Kirenol	Kirenol is a biologically active substance isolated from Herba Siegesbeckiae. It has been reported to possess anti-oxidant, anti-inflammatory, anti-allergic, anti-adipogenic, and anti-arthritic activities.
E3624	Phytolaccae Radix Extract	Phytolaccae Radix Extract is extracted from Phytolaccae Radix (the dried root of Phytolacca acinosa Roxb. or Phytolacca americana L.). Radix Phytolaccae is widely used for the treatment of inflammation-related diseases.
E3735	Ficus hirta Vahl Extract	Ficus Hirta Vahl Extract is derived from Ficus hirta Vahl. (Wuzhimaotao), which possesses hepatoprotective, antibacterial, and anti-inflammatory bioactivities and improves memory function of AD mice.
S9298	Corylin	Corylin, a main compound isolated from Psoralea corylifolia L. (Fabaceae), has a variety of pharmacological effects such as antioxidant, anti-proliferation, and anti-inflammatory properties.
S9300	Methylprotodioscin	Methyl protodioscin, a bioactive natural compound isolated from Dioscorea collettii Makino (Dioscoreaceae), has numerous pharmacological activities, including anti-inflammation, lipid-lowering, and anticancer activities.
E3627	Belamcandae Rhizoma Extract	Belamcandae Rhizoma Extract is extracted from dry roots of Belamcanda chinensis (L.) DC.. Belamcanda chinensis is mainly used to treat sore throat, bronchitis, and chronic tracheitis. Isoflavonoids, including irigenin, isolated from the rhizome of Belamcanda chinensis have been suggested to possess not only antioxidative and anti-inflammatory, but also antitumor activities.
S5261	Ufenamate	Ufenamate (Butyl flufenamate, Flufenamic acid butyl ester, Fenazol) is an anthranilic acid derivative with anti-inflammatory activity.
E3629	Lycopodii Herba Extract	Lycopodii Herba Extract is extracted from Lycopodii Herba, the dried whole plant of Lycopodium japonicum Thunb. (Lycopodiaceae). Lycopodii Herba possesses anti-inflammation activity, antioxidative activity, and antitumor activity; and has been traditionally used for the prevention and treatment of various diseases such as rheumatoid arthritis, contusion, quadriplegia, dysmenorrhea.
E0760	Neotuberostemonine	Neotuberostemonine (NTS), one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, has a significant effect on BLM-induced pulmonary fibrosis by inhibiting macrophage recruitment and M2 polarization protective effect.
E3275	Nigella Sativa Extract (Seed)	Nigella Sativa Extract (Seed) is extrcated from the seeds of Nigella Sativa and may include antidiabetic, anticancer, immunomodulator, analgesic, antimicrobial, anti-inflammatory, and antioxidant properties.
E3822	Coix Lacryma-Jobi Seed Extract	Coix lacryma-jobi seed Extract is extracted from Coix lacryma-jobi L.. Coix lacryma-jobi seed has anti-inflammatory activity, hypoglycemic activity, the ability to decrease the amount of lipid components in the serum and hypocholesterolemic activity.
E4868	Olsalazine	Olsalazine is a salicylic acid-derived anti-inflammatory agent used to treat ulcerative colitis.
E3632	Rehmanniae Radix Extract	Rehmanniae Radix Extract is extracted from Rehmannia to treat skeletal diseases in traditional Chinese medicine and is a potent anti-osteoporotic.
E3327	Chinese Fevervine Herb Extract	Chinese Fevervine Herb Extract is extrcated from Paederia foetida, which is used in the treatment of inflammation, piles, and diarrhea.
S9013	Paulownin	Paulownin, a furofuran lignan from Paulownia tomentosa, has anti-inflammation, analgesia, immunity, hypoglycemia properties.
E3226	Devil's Claw Extract	Devil'S Claw Extract is extracted from Harpagophytum, which is used in a wide range of health conditions, including indigestion, fever, allergic reactions, and rheumatism.
S3780	Secoisolariciresinol diglucoside	Secoisolariciresinol diglucoside (SDG), a plant lignan isolated from flaxseed, has strong antioxidant activity, cardioprotective effects, reduces the blood levels of low-density lipoprotein cholesterol, and reduces the risk of hormone related cancer.
E3063	Pygeum Topengii Bark Extract	Pygeum Topengii Bark Extract is extracted from the bark of Pygeum Topengii, which helps with prostate and kidney health and general inflammation.
S9313	Atractylenolide III	Atractylenolide III, a major component of Atractylodes rhizome, has anti-inflammatory and anti-angiogenesis activities.
S4832	Tolmetin	Tolmetin (Tolectin) is a nonsteroidal anti-inflammatory drug of the heterocyclic acetic acid derivative class and also exhibits analgesic and antipyretic activity.
S9022	20S-Ginsenoside Rg3	20S-Ginsenoside Rg3 is extracted from traditional Chinese medicine, red ginseng. It exihits neuromodulatory, cognition enhancing, anti-inflammatory, antioxidative, anti-angiogenic, and anticancer activities.
E3337	Larva of a Silkworm with Batrytis Extract	Larva Of A Silkworm With Batrytis Extract is extracted from the lara of a Bombyx with batrytis, which is used in the treatment of allergic rhinitis.
S9023	20S-Ginsenoside Rh2	20S-Ginsenoside Rh2 is a ginsenoside found in Panax species and inhibits cancer development, progression, and metastasis.
E3361	Calendula officinalis flower Extract	Calendula Officinalis Flower Extract is extracted from the flowers of Calendula Officinalis, which has wound healing properties.
S9317	Forsythoside A	Forsythoside A, one of the main active ingredients in Forsythiae fructus, has been shown to possess anti-bacterial and immunomodulatory properties.
S9318	(20R)-Ginsenoside Rh1	(20R)-Ginsenoside Rh1, isolated from the root of Panax Ginseng, exhibits various pharmacological activities including vasorelaxation, antioxidation, anti-inflammation, and anticancer.
S4835	Aceclofenac	Aceclofenac (Preservex, Airtal) is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic properties.
S9324	Alnustone	Alnustone, a naturally occuring compound found in the rhizomes of Curcuma xanthorrhiza, exhibits anti-inflammatory, antihepatotoxic and antiemetic activities.
E3374	Exocarpium Citri Rubrum Extract	Exocarpium Citri Rubrum Extract is extrcated from Exocarpium Citri Rubrum, which protects the stomach and eliminates dampness and phlegm.
E3759	Periploca Sepium Extract	Periploca Sepium Extract is derived from Periploca sepium, which has traditionally been used in oriental medicine for treatment of rheumatoid arthritis (RA).
S3893	Bornyl acetate	Bornyl acetate (Isobornyl, Bornyl acetic ether, 2-Camphanol), the main volatile constituent in numerous conifer oils and some Chinese traditional herbs, exhibits anti-inflammatory property and it is used as an analgesic.
E3351	Abrus mollis Extract	Abrus mollis Extract is extracted from Abrus mollis, which is used as a folk beverage and soups that are good to cleanse liver toxicants and prevent liver diseases.
E3377	Symphytum officinale Extract	Symphytum officinale Extract is extracted from Symphytum officinale, which is commonly used in folk medicine to promote wound healing, reduce inflammation and in the treatment of broken bones.
E3378	Selaginella Extract	Selaginella Extract is extracted from Selaginella, which has considerable biological properties and can be used in pain management in emerging nursing care.
S9053	Irisflorentin	Irisflorentin derived from the roots of Belamcanda chinensis (L.) DC. is an herb which has been used for the treatment of inflammatory disorders in traditional Chinese medicine.
E3505	Hibiscus syriacus flower Extract	Hibiscus syriacus flower Extract is extracted from the flowers of Hibiscus syriacus, which has compounds that help in skin regeneration and hydration.
S4682	Loxoprofen	Loxoprofen (Koloxo, Loxoprofene, Loxoprofeno) is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group.
E3503	Papaya Leaf Extract	Papaya Leaf Extract is extracted from the leaves of Carica papaya, which has anticancer, anti-inflammatory, antidiabetic, and antiviral activities.
S3765	Picroside II	Picroside II (6-Vanilloylcatalpol, Vanilloyl catalpol) is the main active ingredient in iridoid glycosides, which is the principal component of Picrorrhiza kurroa Royle. It has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities.
S9051	Asperuloside	Asperuloside, an iridoid glycoside found in Herba Paederiae, is a component from traditional Chinese herbal medicine and exerts anti-inflammatory effect.
S6593	Methylprednisolone sodium succinate	Methylprednisolone sodium succinate (U-9088, 6α-Methylprednisolone 21-hemisuccinate Sodium) is a corticosteroid medication that reduces inflammation.
S9037	Tenacissoside H	Tenacissoside H, a natural compound found in M. tenacissima, exerts anti-inflammatory and anti-tumor effects.
E2699	Tris(2-butoxyethyl) phosphate	Oral exposure to low-dose Tris (2-butoxyethyl) phosphate (TBEP) levels equivalent to tolerable daily intake may exacerbate allergic pulmonary inflammation by promoting a skewed T-helper 2 cell response, upregulation of ERα and dysregulation of both MLN and BM microenvironments.
E3387	Sophora flavescens Extract	Sophora Flavescens Extract is extracted from Sophora flavescens, which is used in the treatment of ulcerative colitis with damp-heat accumulation syndrome.
S3774	Dehydroandrographolide Succinate Potasium Salt	Dehydroandrographolide Succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect.
S3775	Ligustrazine hydrochloride	Ligustrazine hydrochloride (Tetramethylpyrazine, Tetrapyrazine) is a chemical compound found in natto and in fermented cocoa beans with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.
S6404	Salicylamide	Salicylamide (o-hydroxybenzamide) is a non-prescription drug with analgesic and antipyretic properties.
S3776	Sophoricoside	Sophoricoside (SOPH) is an isoflavone isolated from Sophora japonica (Leguminosae) with numerous pharmacological effects, including anti- inflammatory, anti-cancer and immunosuppressive effects.
E3397	Coltsfoot Extract	Coltsfoot Extract is extracted from Tussilago farfara, which is used for relieving inflammatory conditions, as well as respiratory and infectious diseases in humans.
S9067	Pseudoprotodioscin	Pseudoprotodioscin is a steroidal saponin from plants and exhibits anti-inflammatory and anticancer activities. This compound inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides.
S9036	(20R)Ginsenoside Rh2	(20R)Ginsenoside Rh2, a natural compound found in Panax ginseng, shows antiviral and anticancer activities. It is a matrix metalloproteinase (MMP) inhibitor.,
S9068	Trillin	Trillin (Disogluside, Diosgenin glucoside) is an active ingredient isolated from Trillium tschonoshii Maxim and acts as a potential anti-inflammatory drug for chronic hepatic inflammation.
S9384	Sophocarpine Monohydrate	Sophocarpine, a naturally occurring tetracyclic quinolizidine alkaloid derived from Sophora alopecuroides L, has shown promising therapeutic properties, including anti-inflammatory, anti-nociceptive, and antivirus activities.
E6059^New	prednisolone hemisuccinate	Prednisolone hemisuccinate (Prednisolone 21-hemisuccinate) is a synthetic glucocorticoid with anti-inflammatory properties. It is used in the treatment of inner ear diseases and vertigo caused by vestibular hypofunction.
S5044	Isoxepac	Isoxepac is a non-steroidal arylacetic acid derivative with anti-inflammatory, analgesic and antipyretic activity.
E3404	Raphanus sativus seed Extract	Raphanus sativus seed Extract is extracted from the seeds of Raphanus sativus, which has wound-healing characteristics.
S5046	Clonixin	Clonixin (Clonixic acid) is a nonsteroidal anti-inflammatory drug with analgesic, antipyretic, and platelet-inhibitory actions.
S3790	Methyl gallate	Methyl Gallate (Methylgallate, Gallic acid methyl ester, Gallicin) is a plant polyphenol with antioxidant, anticancer, and anti-inflammatory activities.
S5162	Isovanillic acid	Isovanillic acid (Acide isovanillique, 3-Hydroxyanisic acid, 3-Hydroxy-p-anisic acid), a metabolite of isovanillin, is a selective inhibitor of neutrophil migration into inflamed tissue.
S9083	Rhapontin	Rhapontin (Ponticin, Rhaponticin, Rhapontigenin glucoside), a stibene-type glycoside distributed widely in medicinal plants of Rheum genus (Polygonaceae), has anti-inflammatory effect and anti-proliferative activity.
S9084	Rhoifolin	Rhoifolin (Rhoifoloside, Apigenin 7-O-neohesperidoside, Apigenin-7-O-rhamnoglucoside), a natural glycoside of apigenin, has been obtained from the green leaves of Rhus succedanea and possesses a variety of significant biological activities including antioxidant, anti-inflammatory, antimicrobial, hepatoprotective and anticancer effects.
S3799	Gentisic acid	Gentisic acid (2,5-dihydroxybenzoic acid, 5-Hydroxysalicylic acid, Hydroquinonecarboxylic acid, DHB), an active metabolite of salicylic acid degradation, has a broad spectrum of biological activity, such as anti-inflammatory, antirheumatic and antioxidant properties.
S9085	Corynoline	Corynoline is one of the major active components of many ethnopharmacological plants and exhibits anti-tumor, anti-inflammatory and hepatoprotective activities, etc.
S9405	Sesamoside	Sesamoside, a main chemical ingredient iridoid glycoside from Lamiophlomic rotata, has analgesic and anti-inflammatory effects in animal studies.
E3696	Panax notoginseng Extract	Panax notoginseng Extract is is made from the dry roots of Panax notoginseng, which is used to treat inflammation and bleeding, also inhibits Streptococcus pyogenes without affecting oral commensal bacteria.
S9088	Calycosin-7-O-beta-D-glucoside	Calycosin-7-O-beta-D-glucoside, an isoflavone glycoside isolated from A. mongholicus and A. membranaceus, has antioxidant, anti-inflammatory, and neuroprotective biological activities.
S9406	Sauchinone	Sauchinone, one of the active lignan isolated from the roots of Saururus chinensis, possesses diverse pharmacological properties, such as hepatoprotective, anti-inflammatory and anti-tumor effects.
S9407	Angoroside C	Angoroside C, an important phenylpropanoid glycoside of the traditional Chinese medicine Scrophulariae Radix, possesses the effects of preventing ventricular remodeling, reducing pulmonary oedema, and reducing blood pressure, as well as having the properties of anti-platelet aggregation, hepatoprotection and anti-nephritis, etc.
S9408	Beta-Elemonic acid	Beta-Elemonic acid (3-Oxotirucallenoic Acid), a known triterpene isolated from Boswellia (Burseraceae), exhibits anti‑inflammatory effects.
S9091	10-Gingerol	10-Gingerol is a bioactive compound found in ginger with anti-inflammatory and antioxidant activity.
E4964	ATP disodium trihydrate	ATP disodium trihydrate, is the primary energy currency of the cell, essential for intracellular energy metabolism. It regulates extracellular biological processes, including cardiac function, neurotransmission, muscle contraction, vasodilation, bone and liver glycogen metabolism, and inflammation. It also plays a crucial role in initiating immune responses during infections.
E3704	Rumex madaio Makino Extract	Rumex Madaio Makino Extract is derived from Rumex madaio Makino (Polygonaceae), leaf and root tissues of which can be used as medicine such as clearing heat and detoxification, removing blood stasis, and defecating and killing insects.
S9095	Senegenin	Senegenin (Tenuigenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and antiinflammatory activity.
S5834	p-Coumaric acid ethyl ester	p-Coumaric acid ethyl ester is the ethyl ester of p-Coumaric acid, which is a plant metabolite which exhibits antioxidant and anti-inflammatory properties.
S9512	1,3-Dicaffeoylquinic acid	1,3-Dicaffeoylquinic acid (Cynarin; Cinarine; 1,5-Dicaffeoylquinic acid) is a phenolic compound found in artichoke. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent.
E3124	Cirsii Japonici Herba Extract	Cirsii Japonici Herba Extract is extracted from Cirsii Japonici, which can be used in the treatment of chronic glomerulonephritis.
S9098	Dehydrodiisoeugenol	Dehydrodiisoeugenol, a naturally occurring lignan from Aristolochia taliscana (Aristolochiaceae), acts as a potent anti-inflammatory agent and shows various pharmacological activities, including anti-lipid peroxidation, anti-bacteial function, and hepatic drug metabolism enzyme inhibition.
E4724^New	MGD-28	MGD-28 is a potent and orally active degrader of Cereblon (CRBN)-dependent IKAROS proteins. It effectively degrades IKZF1 (DC50 = 3.8 nM), IKZF2 (DC50 = 56.3 nM), and IKZF3 (DC50 = 7.1 nM). It demonstrates significant antiproliferative potency across various hematologic cancer cell lines.
S9099	Orientin	Orientin (Lutexin, Luteolin-8-glucoside), isolated from medicinal plants, has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects.
E5961^New	ZSH-2208	ZSH‐2208 is a RARγ-selective retinoic acid analogue that exhibits potent anti-tumor effects in oesophageal squamous cell carcinoma (ESCC). It inhibits ESCC tumour-repopulating cells (TRCs) by downregulating TNFAIP3, thereby suppressing proliferation and promoting apoptosis.
S9100	Fraxinellone	Fraxinellone is a natural product isolated from the D. dasycarpus plant, which has been shown to exhibit neuroprotective and anti-inflammatory activities.
E3713	Vaccariae semen Extract	Vaccariae semen Extract is drawed from the dried ripe seed of Vaccaria hispanica (Mill.) Rauschert, which has been used to treat stranguria disease, e.g. benign prostatic hyperplasia (BPH) and urinary infection.
E3714	Clematis chinensis Extract	Clematis Chinensis Extract is derived from the dry root of Clematis chinensis Osbeck (Ranunculaceae), which is widely used in the management of various arthritis related conditions.
E3715	Crinum Asiaticum Extract	Crinum Asiaticum Extract is drawed from Crinum asiaticum L. var. sinicum (Roxb. ex Herb.) Baker, which is applied in clinic for the treatment of anti-inflammatory, activating blood, especially purpura, rheumatic arthralgia, traumatic injury and also used to treat cancer nowadays.
S9425	Trifolirhizin	Trifolirhizin, a natural pterocarcan flavonoid extracted from Sophora flavescens, has many pharmacological activities, such as hepatoprotective, anti-inflammatory, anti-proliferation, and skin-whitening.
E3717	Lactuca sativa Extract	Lactuca Sativa Extract is derived from Lactuca sativa (Compositae), the seeds of this plant are used for relieving of inflammation and osteodynia.
E3718	Glaucescent Fissistigma Root Extract	Glaucescent Fissistigma Root Extract is obtained from the root of Fissistigma glaucescens (Hance) Merr. (Annonaceae), which may play an anti-tumor role by improving immune function.
S5579	Chelidonic acid	Chelidonic acid (Jerva acid, Jervaic acid, γ-Pyrone-2,6-dicarboxyl acid) is a secondary metabolite found in several plants with therapeutic potential in allergic disorders in experimental animals. This compound inhibits IL-6 production by blocking NF-κB and caspase-1 in HMC-1 cells. It is also an inhibitor of glutamate decarboxylase with Ki of 1.2 μM.
E5767	Ovalbumins	Ovalbumin is a major glycoprotein found in egg whites, serving as a nutrient reserve for developing embryos and used in the food industry. It also induces a Th2 immune response in sensitized individuals, characterized by the production of cytokines like IL-4, IL-5, and IL-13, leading to airway inflammation, hyper-responsiveness (AHR), and immune cell infiltration, key features in asthma models.
S9431	Dehydrocorydalin	Dehydrocorydalin is an alkaloidal component isolated from Rhizoma corydalis. It has anti-inflammatory and anti-tumor effects and can protect the cardiovascular system.
E3145	Kochiae Fructus Extract	Kochiae Fructus Extract is obtained from dried fruit of Kochia scoparia (L.) Schrad., broom cypress fruit), has attracted considerable attention for its pharmacological activities, including antiinflammation, antidiabetics, insecticide, antianaphylaxis, antipruritic and anti-rheumatoid arthritis.
E3722	Zaocys dhumnades Extract	Zaocys Dhumnades Extract is derived from the dried body of adult Zaocys dhumnades, which is effective in the dispelling cold or wind, dredging meridians, sedation, and mainly used in the treatment of rheumatism, leg and hand’s numb, paraplegic, twitching spasms, as well as tetanus, leprosy acariasis in China and other Asian countries.
S9112	Kaempferitrin	Kaempferitrin (Lespenefril, Lespedin, Lespenephryl, Kaempferol 3,7-dirhamnoside), isolated from the leaves of Hedyotis verticillata and from Onychium japonicum, has antimicrobial, antioxidant, and anti-inflammatory activities.
S9113	Ononin	Ononin (Formononetin glucoside, Formononetin 7-O-glucoside) is an isoflavone glycoside with anti-inflammtory effects.
S9433	Tubeimoside II	Tubeimoside II (Tubeimoside B), a natural triterpenoid saponin isolated from herb, show anti-inflammatory, antitumor, and antitumor-promoting effects.
E0202	Benzoylmesaconine	Benzoylmesaconine (Mesaconine 14-benzoate) is a main Aconitum alkaloid isolated from several Aconitum species with potent pharmacological activities, such as analgesia and anti-inflammation.
S9116	Chikusetsusaponin IVa	Chikusetsusaponin IVa (Calenduloside F), a major active ingredient of triterpenoid saponins, has numerous pharmacological activities, including cytotoxic activity against various cancer cells, anti-inflammatory activity, prevention of dental caries and induction of genta-micin nephrotoxicity. This compound is a novel AMPK activator.
E3739	Panax quinquefolium Extract	Panax Quinquefolium Extract is extracted from Panax quinquefolium L. (American Ginseng, AG), its active compounds—ginsenosides—have been documented to exert a wide range of different biological activities resulting in hypoglycemic, anti-inflammatory, cardio protective, and anti-tumor effects.
S6448	Ibuprofen piconol	Ibuprofen piconol (U75630) is a non-steroidal, anti-inflammatory (NSAID) drug for the topical relief of primary thermal burns and sunburns.
E0205	Strictosamide	Strictosamide is the main representative constituent of Nauclea officinalis Pierre ex Pitard (Rubiaceae) with anti-inflammatory and analgesic activities.
S3106	Pidotimod	Pidotimod(Pidotomod) is an immunostimulant.
S9439	Kaurenoic acid	Kaurenoic acid (kaurenoate, kaur-16-en-18-oic acid) is a natural diterpenoid found in the herbs of Croton antisyphiliticus. This compound has anti-inflammatory activity, the mechanisms may through inhibition of iNOS and COX-2 expression.
S9440	Naringenin chalcone	Naringenin chalcone (Chalconaringenin, Isosalipurpol, trans-2'4'6'4-tetrahydroxychalcone) is the main active component of tomato skin extract, has been proposed as an antioxidant, an anti-inflammatory, and a regulator of fat and sex hormone metabolism.
S6472	Tinoridine hydrochloride	Tinoridine hydrochloride (Y-3642) is a non-steroidal anti-inflammatory drug with a potent antiperoxidative activity.
S9123	Eriodictyol	Eriodictyol, a flavonoid extracted from yerba santa, has anti-inflammatory and antioxidant activities and taste-modifying properties.
S9125	Apigetrin	Apigetrin (Cosmetin, Cosmosioside, Thalictiin, Cosmosin, Apigenin 7-glucoside), a flavonoid found in many plant leaves and seeds, has been known to possess antimutagenic, anti-cancer, antioxidant and anti-inflammatory properties.
E3748	Epimedium Extract	Epimedium Extract is extracted from Epimedium, which has been preliminarily proven to show anti-osteoporotic and anti-inflammatory effects in OA.
S9128	Isoacteoside	Isoacteoside, a phenylethanoid isolated from Monochasma savatieri Franch. ex Maxim., is an anti‐inflammatory herb widely used in traditional Chinese medicine.
S9129	20(S)-Ginsenoside Rh1	20(S)-Ginsenoside Rh1 (Prosapogenin A2, Sanchinoside B2, Sanchinoside Rh1) is one of major bioactive compounds extracted from red ginseng, which has been increasingly used for enhancing cognition and physical health worldwide. It exhibits potent characteristics of anti-inflammatory, antioxidant, immunomodulatory effects, and positive effects on the nervous system. Ginsenoside Rh1 inhibits the expression of PPAR-γ, TNF-α, IL-6, and IL-1β.
E3164	Malvae Fructus Extract	Malvae Fructus Extract is extracted from Malvae Fructus, which helps to open the veins, induce diuresis and disperse swelling, dry pus, relieve diarrhea, quench thirst, and is used to treat ischuria and bladder stones.
E3750	Opuntia dillenii Extract	Opuntia Dillenii Extract is extracted from Opuntia dillenii Haw (Nagphana), which is traditionally used against inflammation.
E3462	Coriaria Root Extract	Coriaria Root Extract is extracted from the roots of coriaria, which is used to treat numbness, toothaches due to wind and heat, phlegm-retention syndrome, traumatic injury, and acute conjunctivitis.
S9132	Harpagide	Harpagide, isolated from the secondary roots of Harpagophytum procumbens (Hp), has valuable medicinal properties, such as anti-inflammatory, analgesic and potential antirheumatic effects.
E3470	Mango leaf Extract	Mango Leaf Extract is extracted from the leaves of Mangifera indica, which attenuates muscle pain and damage and accelerates the recovery of muscle performance.
S4789	5-Acetylsalicylic acid	5-Acetylsalicylic acid (5-acetyl-2-hydroxybenzoic acid) is a nonsteroidal anti-inflammatory drug.
E3472	Spicate clerodendranthus Extract	Spicate Clerodendranthus Extract is extracted from Spicate Clerodendranthus, which has curative effects on respiratory inflammation and upper respiratory diseases such as parched mouth, kakostomia, and bitter taste.
E3473	Ternate buttercup root Extract	Ternate Buttercup Root Extract is extracted from the roots of Ternate Buttercup, which boosts the activity of the immune system, reduces inflammation, scavenges damaging particles known as free radicals, and destroys cancerous cells.
E3767	Justicia Gendarussa Extract	Justicia Gendarussa Extract is obtained from Justicia gendarussa, which is useful in asthma, rheumatism and colics of children, also may have the potential to be the basis for a birth control pill for men.
S9144	Solasonine	Solasonine, a natural glycoalkaloid compound, has anti-inflammation and anti-tumor properties.
E3477	Rose hip Extract	Rose Hip Extract is extracted from the fruits of Rosa L., which is used to treat kidney stones, gastro-enteric ailments, hypertension, and respiratory problems such as bronchitis, cough, and colds.
S9220	Stylopine hydrochloride	Stylopine (Tetrahydrocoptisine, Coptisine), a major component of the leaf of Chelidonium majus L., is a protoberberine-type alkaloid that has potential biological activities, including anti-inflammatory activity.
E3482	Buddleja Officinalis Extract	Buddleja Officinalis Extract is drawed from Buddleja officinalis flower, which is reportedly effective in treating inflammation, conjunctival hypertension, and headache in traditional oriental herbal medicine.
S5043	Benorylate	Benorylate (Benorilate, Benoral, Benortan) is the esterification product of paracetamol and acetylsalicylic acid with anti-inflammatory, analgesic and antipyretic properties.
E0208	Herbacetin	Herbacetin is a natural flavonoid compound found in flaxseed with strong antioxidant, antitumor and anti-inflammatory activity.
E3001	Donkey-hide gelatin Extract	Donkey-Hide Gelatin Extract is extracted from Donkey-hide gelatin (Asini Corii Colla, ACC), a gelatinous Chinese medicine known as Ejiao in Chinese. Donkey-hide gelatin is applied as an important food therapy product to optimize immune response, improve metabolic balance and treat gynecological diseases.
E0193	Mometasone Furoate Hydrate	Mometasone Furoate (SCH 32088) Hydrate is a synthetic glucocorticoid with anti-inflammatory activity.
S9157	Neoandrographolide	Neoandrographolide, a principle diterpenoids isolated from A. paniculata, exerts a wide range of therapeutic actions, including immunosuppressant, antithrombotic, anti-inflammatory, antineoplastic, anti-viral, anti-bacterial, anti-diabetic, anti-oxidative stress, antipyretic, anti-edematogenic, and anti-nociceptive activities.
S4524	2-Ethoxybenzamide	2-Ethoxybenzamide (Ethenzamide) is a common analgesic and anti-inflammatory drug that is used for the relief of fever, headaches, and other minor aches and pains.
E3497	Momordicae Semen Extract	Momordicae Semen Extract is extracted from Momordicae semen, which has anti-gastritis and wound healing effects.
S5463	Curcurbitacin IIA	Curcurbitacin IIA (Cucurbitacin Iia, CuIIa, Hemslecin A, Dihydrocucurbitacin Q1) is a triterpene isolated from Hemsleya amalils Diels, induces apoptosis of cancer cells, reduces expression of survivin, reduces phospho-Histone H3 and increases cleaved PARP in cancer cells.
S9161	Ziyuglycoside II	Ziyuglycoside II is an active compound of Sanguisorba officinalis L. that has anti-inflammation, antioxidation, antibiosis, and homeostasis properties.
E3787	Flos Inulae Extract	Flos Inulae Extract is drawed from Flos Inulae, which can be applied to antimutation, antityrosinase and anti-inflammation.
S3906	Astragalus polyphenols	Astragalus polyphenols(2,3,5,4'-Tetrahydroxystilbene-2-O-beta-D-glucopyranoside) is a wonderful immune enhancing herb that has strong anti-viral activity and produces extra interferon in the body. It contains rich polyphenol with various effects including antioxidant and antiinflammatory actions.
S9551	Uvaol	Uvaol is a pentacyclic triterpene, found in the non-glyceride fraction of olive pomace oil, exhibiting both pro- and anti-inflammatory properties.
E3789	Saussurea Involucrata Extract	Saussurea Involucrata Extract is drawed from the flower of Saussurea involucrata Matsum. & Koidz., which has long been used to treat rheumatoid arthritis, cough with cold, stomach ache, dysmenorrhea, and altitude sickness in Uyghur and Chinese medicine.
S9165	Poncirin	Poncirin (Isosakuranetin-7-neohesperidoside), extracted from trifoliate orange, has anti-bacterial and anti-inflammatory activities.
S9167	Columbin	Columbin, a diterpenoid furanolactone, is a potential anti-inflammatory drug.
S9560	Anisodamine Hydrobromide	Anisodamine (6-Hydroxyhyoscyamine) is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs).
E0233	14-Deoxy-11,12-didehydroandrographolide	14-Deoxy-11,12-didehydroandrographolide (deAND), a diterpenoid in Andrographis paniculata (Burm. f.) Nees with hypotensive, anti-inflammatory, anti-asthma, and anti-cancer activities.
E3791	Surgentodoxa Cuneata Extract	Surgentodoxa Cuneata Extract is drawed from Surgentodoxa Cuneata, which has anti-inflammatory, antioxidant, antitumor, antimicrobial, and anti-sepsis activities.
E3793	Urtica Fissa Extract	Urtica Fissa Extract is extracted from Urtica fissa (Urticaceae), rhizomes (Urticae Rhizoma, Qianma Gen in Chinese) of which is a commonly-used enthnomedicine for the treatment of rheumatism and urticaria in Chinese traditional medicine.
S9171	Harpagoside	Harpagoside, a natural product found in the plant Harpagophytum procumbens, has potent anti-rheumatic, anti-inflammatory and analgesic effects.
E3500	Agaric Extract	Agaric Extract is extracted from agaricales, which has anti-inflammatory and related pharmacological activities.
S9172	Phellodendrine	Phellodendrine, a quaternary ammonium alkaloid extracted from the dried bark of Phellodendrom chinensis Schneid and Phellodendrom amurense Rupr, has the effect of suppressing cellular immune response, reducing blood pressure and antinephritis.
S6742	Etofenamate	Etofenamate is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain.
E3501	Hibiscus mutabilis flower Extract	Hibiscus Mutabilis Flower Extract is extracted from the flowers of Hibiscus mutabilis, which has allergy-preventive effects.
S9175	Macranthoidin A	Macranthoidin A, found in the herbs of Lonicera japonica Thunb., has anti-inflammation activity.
S9180	Tussilagone	Tussilagone, isolated from the flower of buds of Tussilago farfara (Compositae), is a sesquiterpenoid that is used as a traditional oriental medicine for asthma and bronchitis. It shows anti-inflammatory activity in in vitro studies.
S5729	Fosfosal	Fosfosal (2-phosphonoxy benzoic acid) is a non-acetylated salicylic acid derivative, with analgesic and anti-inflammatory activity, but without effects on PG biosynthesis in vitro.
S5451	Ferulic acid methyl ester	Ferulic acid methyl ester (Methyl Ferulate, Methyl 4'-hydroxy-3'-methoxycinnamate) is a lipophilic derivative of ferulic acid, which is a hydroxycinnamic acid that is abundant in plants. It shows the strongest antioxidant activity and can protect against inflammation and cancer.
S9184	Forsythoside B	Forsythoside B is a phenylethanoid glycoside isolated from the leaves of Lamiophlomis rotata Kudo, a Chinese folk medicinal plant. This compound has potent neuroprotective effects and has anti-inflammation, antioxidant, and antisepsis properties. It could inhibit TNF-alpha, IL-6, IκB and modulate NF-κB.
S4169	Teriflunomide	Teriflunomide (A77 1726, HMR-1726) is the active metabolite of leflunomide, inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase, used as an immunomodulatory agent.	J Clin Invest, 2025, e190215 Front Cell Dev Biol, 2023, 11:1089945 Cell Death Discov, 2022, 8(1):464
S2350	Rutin	Rutin (Rutoside), a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human.	J Virol, 2025, e0209524. Biology (Basel), 2025, 14(5)527 Journal of Virology, 2025, e02095-24
S5260	ATP (Adenosine 5'-triphosphate)	ATP (Adenosine-Triphosphate, Adenosine 5'-triphosphate) is a multifunctional nucleoside triphosphate and an important endogenous signaling molecule in immunity and inflammation.	Adv Sci (Weinh), 2025, 12(40):e09838 Stem Cell Res Ther, 2025, 16(1):206 Cell Rep, 2024, 43(2):113779
S1681	Mesalazine (5-ASA)	Mesalazine (5-ASA) is a specific inhibitor of TNFα-induced IKK activity, used to treat inflammatory bowel disease.	Nat Commun, 2025, 16(1):1826 Phytomedicine, 2025, 146:157096 J Nutr Biochem, 2024, 136:109804
S3871	Muscone	Muscone (3-Methylcyclopentadecanone, Methylexaltone), a flavouring ingredient, is an organic compound that is the primary contributor to the odor of musk and also a potent anti-inflammatory agent. This compound significantly downregulats the levels of LPS-induced inflammatory cytokines and inhibits NF-κB and NLRP3 inflammasome activation in BMDMs. It remarkably decreases the levels of inflammatory cytokines (IL-1β, TNF-α and IL-6).	Ecotoxicol Environ Saf, 2025, 292:117961 Invest Ophthalmol Vis Sci, 2025, 66(5):21 Toxicol Appl Pharmacol, 2025, 503:117494
S8097	C-DIM12	C-DIM12 is a Nurr1 activator that stimulates this compound mediated apoptosis axis in bladder cancer cells and tumors and inhibits NF-κB–dependent gene expression in glial cells.	Frontiers in Molecular Neuroscience, 2020, 64 Front Mol Neurosci, 2020, 23724 Cell Death Dis, 2018, 9(3):411
S2400	Rheic Acid	Rhein (Monorhein, NSC 38629, Rheinic) is an anthraquinone compound enriched in the fresh rhizome of Rheum coreanum Nakai, showing anti-inflammation and antitumor activities. Rhein is an FTO (mRNA N⁶-methyladenine demethylase) inhibitor and also inhibits AlkB repair enzymes.	Animals (Basel), 2024, 14(16)2434 Cell Chem Biol, 2016, 23(3):415-25
S9052	Auraptene	Auraptene (7-geranyloxycoumarin) is a natural coumarin derived from citrus plants and possesses valuable pharmacological properties, including anticarcinogenic, anti-inflammatory, antihelicobacter, antigenotoxic, and neuroprotective effects. This compound inhibits matrix metalloproteinase 2 (MMP-2) as well as key inflammatory mediators, including IL-6, IL-8 and chemokine (C-C motif) ligand-5(CCL5).	Neuropharmacology, 2025, 269:110352 Plant Physiology, 2012, 81–94
S2387	Lappaconite HBr	Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects.	Int J Mol Sci, 2018, 19(6)
S3745	Balsalazide disodium	Balsalazide Disodium is the disodium salt form of balsalazide, an aminosalicylate and oral prodrug that is enzymatically cleaved in the colon to produce the anti-inflammatory agent mesalazine. Balsalazide Disodium suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway.	Front Microbiol, 2020, 10:2936
E0212	Cornuside	Cornuside is a bisiridoid glucoside compound isolated from the fruit of Cornus officinalis SIEB. et ZUCC. This compound suppresses lipopolysaccharide-induced inflammatory mediators by inhibiting NF-κB activation in RAW 264.7 macrophages. It attenuates apoptosis in rat cortical neurons.
E3069	Spinach Extract	Spinach Extract is extracted from Spinacia oleracea, which has beneficial effects on gut microbiota and SCFAs.
E3107	Andrographis Herba Extract	Andrographis Herba Extract is obtained from the aerial part of Andrographis paniculata (Burm. F.) Nees, has various activities including antimicrobial and antioxidant, antimalarial, antiangiogenic, anti-inflammatory, anti-diabetic, and in vitro α-glucosidase and α-amylase enzyme inhibitory activities.
E3309	Polygala Fallax Hemsl. Rhizome Extract	Polygala Fallax Hemsl. Rhizome Extract is drawed from the rhizome of Polygala Fallax Hemsl., which has effects on immune function, such as anti-stress, anti-inflammatory, blood activating, lipid regulating, and in vitro inhibition of hepatitis B virus.
S4966	4-Methylesculetin	4-methylesculetin is one of the coumarin derivatives with great anti-oxidant and anti-inflammatory activities. 4-Methylesculetin inhibits myeloperoxidase (MPO) activity and reduces IL-6 level.
S9054	Pectolinarin	Pectolinarin is a major compound in Cirsium setidens with anti-inflammatory activity. This compound inhibits secretion of IL-6 and IL-8, as well as the production of PGE2 and NO. It also induces apoptosis via inactivation of the PI3K/Akt pathway.
S5016	Isoprinosine	Isoprinosine (Inosine pranobex, Immunovir, Groprinosin, Delimmun) is an immunopharmacologic agent with antiviral activities.
S6073	Diclofenac acid	Diclofenac acid is a nonsteroidal anti-inflammatory drug that has analgesic, anti-inflammatory, and antipyretic properties, and has been shown to be effective in treating a variety of acute and chronic pain and inflammatory conditions. It inhibits cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) with relative equipotency.
E3165	Rabdosiae Rubescentis Herba Extract	Rabdosiae Rubescentis Herba Extract is drawed from the dried aerial part of genus Rabdosia rubescens (Hemsl.) Hara of the Lamiaceae family, which possesses several biological activities, such as anti-bacteria, anti-parasites, anti-inflammation, and anticancer.
E3760	Cymbopogon Citratus Extract	Cymbopogon Citratus Extract is derived from Cymbopogon citratus DC (Stapf.), which has antimicrobial, antiprotozoal, anti-rheumatic, antitumoural, cardio-protective, anti-inflammatory and gastroprotective properties.
S9488	Lobetyolin	Lobetyolin is one of the important active ingredients extracted from the root of Codonopsis pilosula, which has a good protective effect on gastric mucosal damage. This compound can downregulate glutamine metabolism, contribute to drug-induced apoptosis and tumor growth inhibition, and it significantly reduces the mRNA and protein expression of the amino acid transporter alanine-serine-cysteine transporter 2 (ASCT2).
E0222	Glaucocalyxin A	Glaucocalyxin A is a biologically active ent-kauranoid diterpenoid isolated from Rabdosia japonica var. glaucocalyx with antitumor and anti-inflammatory activity. This compound induces G2/M cell cycle arrest and apoptosis through the PI3K/Akt pathway in human bladder cancer cells.
S9174	Xanthotoxol	Xanthotoxol (8-Hydroxypsoralen, 8-Hydroxypsoralene, 8-Hydroxyfuranocoumarin, Psoralen), a biologically active linear furocoumarin found in a large number of plants, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects.
E0211	Dihydroberberine	Dihydroberberine, a hydrogenated derivative of Berberine (BBR), exerts anti-inflammatory effect via dual modulation of NF-κB and MAPK signaling pathways.