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ATP (Adenosine 5'-triphosphate) Endogenous Metabolite

Cat.No.S5260

ATP (Adenosine-Triphosphate, Adenosine 5'-triphosphate) is a multifunctional nucleoside triphosphate and an important endogenous signaling molecule in immunity and inflammation.
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Quality Control

Batch: S526002 Water]100 mg/mL]false]DMSO]Insoluble]false]Ethanol]Insoluble]false Purity: 99.98%
99.98

Solubility

In vitro
Batch:

Water : 100 mg/mL

DMSO : Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : Insoluble

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Mass Concentration Volume Molecular Weight
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In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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%
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 507.18 Formula

C10H16N5O13P3

Storage (From the date of receipt) 3 years -20°C powder
CAS No. 56-65-5 -- Storage of Stock Solutions

Read more about storage stability stock solution CAS number

Mechanism of Action

In vitro

ATP, a multifunctional nucleoside triphosphate and an important endogenous signaling molecule, restores signaling responses to anti-TCR treatment in Jurkat cells.

In vivo

ATP can activate the NLRP3 inflammasome and enhance the production of pro-inflammatory cytokines, thus protecting mice against bacterial infection.

References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-09-04)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
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2026-02-01
NCT06924073 RECRUITING
Adolescent HIV Infection; Transition to Adult Care; Implementation Science; Implementation Strategies
University of Washington
2025-10-16
NCT06942572 RECRUITING
Stargardt Disease; Stargardt Macular Degeneration; Stargardt Macular Dystrophy
Splice Bio
2025-02-11 PHASE1; PHASE2
NCT07167966 ENROLLING_BY_INVITATION
Preclinical Alzheimer's Disease; Prodromal Alzheimer's Disease; Alzheimer Disease
Paul S. Aisen
2026-11-03 PHASE2
NCT06921720 RECRUITING
Phosphate Diabetes; X-linked Hypophosphatemia
Hospices Civils de Lyon
2025-05-16
NCT07296354 NOT_YET_RECRUITING
Neuropathic Pain
Egyptian International Pharmaceutical Industries Co
2026-01-10 PHASE4

Read more about Clinical Trials

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