Catalog No.S4165 Synonyms: AF864
Molecular Weight(MW): 345.87
Benzydamine hydrochloride is a topical nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, antipyretic and local anesthetic activity.
Purity & Quality Control
Choose Selective Immunology & Inflammation related Inhibitors
|Description||Benzydamine hydrochloride is a topical nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, antipyretic and local anesthetic activity.|
Benzydamine is structurally unrelated to the corticosteroids. The action of benzydamine may be mediated by the prostaglandin system. The drug may affect formation of thromboxanes and alter biosynthesis of prostaglandin, in doses that can be reached by topical application. Benzydamine displays a stabilizing effect on cell membranes, inhibits degranulation of human polymorphonuclear leukocytes, and inhibits platelet aggregation. Benzydamine may affect aspects of tissue biochemistry relevant to local mechanisms of inflammation and pain. 
|In vivo||Benzydamine significantly lower the incidence of postoperative sore throat (POST). At 6 hours after extubation, the incidence of POST is 17.0%. Spraying benzydamine hydrochloride on the ETT cuff is a simple and effective method to reduce the incidence and severity of POST. |
|In vitro||DMSO||69 mg/mL (199.49 mM)|
|Water||69 mg/mL (199.49 mM)|
|Ethanol||69 mg/mL (199.49 mM)|
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).
Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).
Molecular Weight Calculator
Enter the chemical formula of a compound to calculate its molar mass and elemental composition:
Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2
Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Clinical Trial Information
|NCT Number||Recruitment||Conditions||Sponsor/Collaborators||Start Date||Phases|
|NCT03074968||Completed||Intubation Complication||Seoul National University Hospital||March 8 2017||Phase 4|
|NCT02720783||Completed||Healthy Women||Aziende Chimiche Riunite Angelini Francesco S.p.A|Cross Research S.A.||March 4 2016||Phase 1|
|NCT02713893||Completed||Healthy||Aziende Chimiche Riunite Angelini Francesco S.p.A|Cross Research S.A.||September 2015||Phase 1|
|NCT01637883||Unknown status||For Intervention||Prince of Songkla University||January 2011||Phase 3|
|NCT00814359||Completed||Head and Neck Cancer|Mucositis||Juravinski Cancer Centre Foundation||May 2009||Phase 3|
|NCT00051441||Completed||Stomatitis|Radiation Effects||McNeil Consumer & Specialty Pharmaceuticals a Division of McNeil-PPC Inc.|Angelini||null||Phase 3|
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.