Signaling Pathway Map

Research Area

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S1537 DMXAA (Vadimezan) <1 mg/mL 7 mg/mL <1 mg/mL
S1786 Verteporfin <1 mg/mL 100 mg/mL <1 mg/mL
S1176 Plinabulin (NPI-2358) <1 mg/mL 54 mg/mL <1 mg/mL
Catalog No. Information Product Use Citations Product Validations

DMXAA (Vadimezan)

DMXAA (Vadimezan) is a vascular disrupting agents (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 μM and IC50 of 62.5 μM in cell-free assays, respectively. Phase 3.



Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin.


Plinabulin (NPI-2358)

Plinabulin (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing with IC50 of 9.8~18 nM in tumor cells. Phase 1/2.