PAR

Inhibitory Selectivity

Isoform-specific Inhibitors

PAR Products

Catalog No. Information Product Use Citations Product Validations
S2916

ML161 (Parmodulin 2)

ML161 (Parmodulin 2) is an allosteric inhibitor of PAR1 with IC50 of 0.26 μM.

S9744New

AZ3451

AZ3451 is a potent antagonist of protease-activated receptor 2 (PAR2) that binds to a remote allosteric site outside the helical bundle with IC50 of 23 nM.

S8067

Vorapaxar (MK-5348)

Vorapaxar (SCH 530348, MK-5348) is a potent and orally active thrombin receptor (PAR-1) antagonist with Ki of 8.1 nM.

Catalog No. Information Product Use Citations Product Validations
S2916

ML161 (Parmodulin 2)

ML161 (Parmodulin 2) is an allosteric inhibitor of PAR1 with IC50 of 0.26 μM.

Catalog No. Information Product Use Citations Product Validations
S9744New

AZ3451

AZ3451 is a potent antagonist of protease-activated receptor 2 (PAR2) that binds to a remote allosteric site outside the helical bundle with IC50 of 23 nM.

S8067

Vorapaxar (MK-5348)

Vorapaxar (SCH 530348, MK-5348) is a potent and orally active thrombin receptor (PAR-1) antagonist with Ki of 8.1 nM.