• Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S7421 CGP 57380 <1 mg/mL 48 mg/mL <1 mg/mL
S8275 eFT-508 (eFT508) <1 mg/mL 13 mg/mL <1 mg/mL
Catalog No. Information Product Use Citations Product Validations

CGP 57380

CGP 57380 is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases.


eFT-508 (eFT508)

eFT-508 (eFT508) is a potent and selective MNK1/2 inhibitor with IC50s of 2.4 nM and 1 nM, respectively. It potentially results in decreased tumor cell proliferation and tumor growth.

Tags: MNK activty | MNK inhibitor | MNK inhibitor review