Aldose Reductase

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Aldose Reductase Products

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Catalog No. Product Name Information Product Use Citations Product Validations
S0878 AT-001 AT-001 (Aldose reductase-IN-1) is an aldose reductase inhibitor with IC50 of 28.9 pM.
S2035 Epalrestat (ONO-2235) Epalrestat (ONO-2235) is an aldose reductase inhibitor with IC50 of 72 nM.
Free Radic Biol Med, 2021, 163:220-233
J Agric Food Chem, 2020, 68(42):11747-11757
Int J Med Sci, 2020, 17(9):1246-1256
S2404 Isoliquiritigenin Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, inhibits aldose reductase with an IC50 of 320 nM.
Biomedicines, 2022, 10(3)638
Cancer Res, 2021, 81(16):4257-4274
Transl Vis Sci Technol, 2020, 9(9):39
S3245 Nodakenetin Nodakenetin (NANI), a plant-derived coumarin isolated from Angelica decursiva, inhibits α-glucosidase, PTP1B, rat lens aldose reductase (RLAR), AChE, BChE, and β-site amyloid precursor protein cleaving enzyme 1 (BACE1). Nodakenetin alters the protein expression of Bax and Bcl-2, and prompts mitochondrial apoptosis. Nodakenetin exhibits anti-tumor activity.
S5446 2-Chloro-1-(4-fluorobenzyl)benzimidazole 2-Chloro-1-(4-fluorobenzyl)benzimidazole is an aldose reductase (ALR2) inhibitor which is used for preparation of disubstituted benzimidazole derivative.
S5803 Alrestatin Alrestatin is an inhibitor of aldose reductase which is involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy.
iScience, 2022, 25(4):104153
S9196 Calceolarioside B Calceolarioside B (Nuomioside A), found in the herbs of Ajuga becumbens Thunb., has anti-proliferation property.Calceolarioside B exhibits significant inhibitory activity against rat lens aldose reductase (RLAR) with an IC50 of 23.99 μM. Calceolarioside B displays inhibitory effect on DPPH radical scavenging activity with an IC50 of 94.60 μM.
S0878 AT-001 AT-001 (Aldose reductase-IN-1) is an aldose reductase inhibitor with IC50 of 28.9 pM.
S2035 Epalrestat (ONO-2235) Epalrestat (ONO-2235) is an aldose reductase inhibitor with IC50 of 72 nM.
Free Radic Biol Med, 2021, 163:220-233
J Agric Food Chem, 2020, 68(42):11747-11757
Int J Med Sci, 2020, 17(9):1246-1256
S2404 Isoliquiritigenin Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, inhibits aldose reductase with an IC50 of 320 nM.
Biomedicines, 2022, 10(3)638
Cancer Res, 2021, 81(16):4257-4274
Transl Vis Sci Technol, 2020, 9(9):39
S3245 Nodakenetin Nodakenetin (NANI), a plant-derived coumarin isolated from Angelica decursiva, inhibits α-glucosidase, PTP1B, rat lens aldose reductase (RLAR), AChE, BChE, and β-site amyloid precursor protein cleaving enzyme 1 (BACE1). Nodakenetin alters the protein expression of Bax and Bcl-2, and prompts mitochondrial apoptosis. Nodakenetin exhibits anti-tumor activity.
S5446 2-Chloro-1-(4-fluorobenzyl)benzimidazole 2-Chloro-1-(4-fluorobenzyl)benzimidazole is an aldose reductase (ALR2) inhibitor which is used for preparation of disubstituted benzimidazole derivative.
S5803 Alrestatin Alrestatin is an inhibitor of aldose reductase which is involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy.
iScience, 2022, 25(4):104153
S9196 Calceolarioside B Calceolarioside B (Nuomioside A), found in the herbs of Ajuga becumbens Thunb., has anti-proliferation property.Calceolarioside B exhibits significant inhibitory activity against rat lens aldose reductase (RLAR) with an IC50 of 23.99 μM. Calceolarioside B displays inhibitory effect on DPPH radical scavenging activity with an IC50 of 94.60 μM.
Tags: Aldose Reductase inhibitor|Aldose Reductase agonist|Aldose Reductase activator|Aldose Reductase inducer|Aldose Reductase antagonist|Aldose Reductase signaling pathway|Aldose Reductase assay kit