Home Metabolism Aldose Reductase

Aldose Reductase

Other Metabolism Related Inhibitors

Dehydrogenase Transferase DPP Aminopeptidase Procollagen C Proteinase P450 (e.g. CYP17) Phospholipase (e.g. PLA) Factor Xa PDE DHFR
Cat.No. Product Name Information Product Use Citations Product Validations
S2404 Isoliquiritigenin Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, inhibits aldose reductase with an IC50 of 320 nM.
J Nutr Biochem, 2024, 136:109808
Biomedicines, 2022, 10(3)638
Cancer Res, 2021, 81(16):4257-4274
Verified customer review of Isoliquiritigenin
S2035 Epalrestat Epalrestat is an aldose reductase inhibitor with IC50 of 72 nM.
Cell Rep Med, 2023, 4(6):101056
Cell Rep Med, 2023, 4(6):101056
Free Radic Biol Med, 2021, 163:220-233
S5803 Alrestatin Alrestatin is an inhibitor of aldose reductase which is involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy.
iScience, 2022, 25(4):104153
S9196 Calceolarioside B Calceolarioside B (Nuomioside A), found in the herbs of Ajuga becumbens Thunb., has anti-proliferation property. This compound exhibits significant inhibitory activity against rat lens aldose reductase (RLAR) with an IC50 of 23.99 μM. It also displays inhibitory effect on DPPH radical scavenging activity with an IC50 of 94.60 μM.
E2456 Soyasaponin Bb Soyasaponin Bb, a soyasaponin isolated from Phaseolus vulgaris, is an aldose reductase (AKR1B1) differential inhibitor (ARDI).
S1074 Poliumoside Poliumoside exhibits significant inhibition of advanced glycation end product formation with IC50 values of 19.69 µM. In the rat lens aldose reductase assay. This compound exhibits greater inhibitory effects on rat lens aldose reductase(RLAR) with IC50 values of 8.47 µM.
S5446 2-Chloro-1-(4-fluorobenzyl)benzimidazole 2-Chloro-1-(4-fluorobenzyl)benzimidazole is an aldose reductase (ALR2) inhibitor which is used for preparation of disubstituted benzimidazole derivative.
S9198 Obtusifolin Obtusifolin is anthraquinone found in the seeds of Cassia obtusifolia, has inhibitory effects on platelet aggregation and aldose reductase.
S3245 Nodakenetin Nodakenetin (NANI), a plant-derived coumarin isolated from Angelica decursiva, inhibits α-glucosidase, PTP1B, rat lens aldose reductase (RLAR), AChE, BChE, and β-site amyloid precursor protein cleaving enzyme 1 (BACE1). This compound alters the protein expression of Bax and Bcl-2, and prompts mitochondrial apoptosis. It exhibits anti-tumor activity.