Aldose Reductase

All (4) Aldose Reductase Inhibitors (4)

Catalog No.	Information	Product Use Citations	Product Validations
S9196	Calceolarioside B Calceolarioside B, found in the herbs of Ajuga becumbens Thunb., has anti-proliferation property.Calceolarioside B exhibits significant inhibitory activity against rat lens aldose reductase (RLAR) with an IC50 of 23.99 μM. Calceolarioside B displays inhibitory effect on DPPH radical scavenging activity with an IC50 of 94.60 μM.
S5803	Alrestatin Alrestatin is an inhibitor of aldose reductase which is involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy.
S5446	2-Chloro-1-(4-fluorobenzyl)benzimidazole 2-Chloro-1-(4-fluorobenzyl)benzimidazole is an aldose reductase (ALR2) inhibitor which is used for preparation of disubstituted benzimidazole derivative.
S2404	Isoliquiritigenin Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, inhibits aldose reductase with an IC50 of 320 nM.	Biomed Res Int, 2020, 2020:9259852 Int J Biol Sci, 2019, 15(11):2497-2508 Proc Natl Acad Sci U S A, 2018, 115(42):E9869-E9878	Cells expressing wild type EGFR (HCC827 and H1650) or L858R/T790M mutant EGFR (HCC827GR) were treated with different concentration of ILQ for 24 h, and the expression of apoptotic markers was detected by immunoblotting.

Catalog No.	Information	Product Use Citations	Product Validations
S9196	Calceolarioside B Calceolarioside B, found in the herbs of Ajuga becumbens Thunb., has anti-proliferation property.Calceolarioside B exhibits significant inhibitory activity against rat lens aldose reductase (RLAR) with an IC50 of 23.99 μM. Calceolarioside B displays inhibitory effect on DPPH radical scavenging activity with an IC50 of 94.60 μM.
S5803	Alrestatin Alrestatin is an inhibitor of aldose reductase which is involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy.
S5446	2-Chloro-1-(4-fluorobenzyl)benzimidazole 2-Chloro-1-(4-fluorobenzyl)benzimidazole is an aldose reductase (ALR2) inhibitor which is used for preparation of disubstituted benzimidazole derivative.
S2404	Isoliquiritigenin Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, inhibits aldose reductase with an IC50 of 320 nM.	Biomed Res Int, 2020, 2020:9259852 Int J Biol Sci, 2019, 15(11):2497-2508 Proc Natl Acad Sci U S A, 2018, 115(42):E9869-E9878	Cells expressing wild type EGFR (HCC827 and H1650) or L858R/T790M mutant EGFR (HCC827GR) were treated with different concentration of ILQ for 24 h, and the expression of apoptotic markers was detected by immunoblotting.