Nodakenetin

Catalog No.S3245 Synonyms: NANI

For research use only.

Nodakenetin (NANI), a plant-derived coumarin isolated from Angelica decursiva, inhibits α-glucosidase, PTP1B, rat lens aldose reductase (RLAR), AChE, BChE, and β-site amyloid precursor protein cleaving enzyme 1 (BACE1). Nodakenetin alters the protein expression of Bax and Bcl-2, and prompts mitochondrial apoptosis. Nodakenetin exhibits anti-tumor activity.

Nodakenetin Chemical Structure

CAS No. 495-32-9

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Biological Activity

Description Nodakenetin (NANI), a plant-derived coumarin isolated from Angelica decursiva, inhibits α-glucosidase, PTP1B, rat lens aldose reductase (RLAR), AChE, BChE, and β-site amyloid precursor protein cleaving enzyme 1 (BACE1). Nodakenetin alters the protein expression of Bax and Bcl-2, and prompts mitochondrial apoptosis. Nodakenetin exhibits anti-tumor activity.
Targets
α-glucosidase [1] PTP1B [1] RLAR [1] AChE [1] BChE [1] Click to View More Targets

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 246.26
Formula

C14H14O4

CAS No. 495-32-9
Storage 3 years -20°C powder
2 years -80°C in solvent

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