Home Epigenetics -Methylation DNA Methyltransferase TET Selective Inhibitors

TET Selective Inhibitors

  • TET
  • DNMT1
  • DNMT3
Catalog No. Product Name Information Selective / Pan IC50 / Ki
S6682 Bobcat339 hydrochloride Bobcat339 is a selective cytosine-based TET enzyme inhibitor with IC50 of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 can reduce DNA 5-hydroxymethylcytosine abundance by inhibiting TET enzyme function in living cells and provide support for its utility as a viable pharmacological probe. Selective TET1, IC50: 33 μM; TET2, IC50: 73 μM