Home Methylation -Epigenetics PRMT PRMT8 Inhibitors

PRMT8 Inhibitors

  • PRMT5
  • PRMT4
  • PRMT6
  • PRMT1
  • PRMT8
  • PRMT3
Catalog No. Product Name Information Selective / Pan IC50 / Ki
S8112 MS023 MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8, respectively. Pan PRMT8, IC50: 5 nM
S7820 EPZ020411 2HCl EPZ020411 is a potent and selective small molecule PRMT6 inhibitor with an IC50 of 10 nM. Pan PRMT8, IC50: 223 nM
S8858 GSK3368715 3HCl GSK3368715 3HCl is a potent inhibitor of type I protein arginine methyltransferases (PRMT) that inhibits PRMT1, 3, 4, 6 and 8 with Kiapp vaules ranging from 1.5 to 81 nM. Pan