Home PI3K/Akt/mTOR PDK PDK1 Selective Inhibitors

PDK1 Selective Inhibitors

  • PDK1
  • PDK2
  • PDK3
Catalog No. Product Name Information Selective / Pan IC50 / Ki
S2949 KPLH1130 KPLH1130 is a specific inhibitor of pyruvate dehydrogenase kinase (PDK) that blocks macrophage polarization and attenuates proinflammatory responses. Selective PDK, Ki: 10 μM
S0983 JX06 JX06 is a selective covalent inhibitor of PDK1 in cells. JX06 dose-dependently inhibits PDK1, PDK2 and PDK3 with IC50 0.049 μM, 0.101 μM and 0.313 μM, respectively. Pan PDK1, IC50: 0.049 μM