Home GPCR & G Protein Endothelin Receptor ET-B Antagonists

ET-B Antagonists

  • ET-A
  • ET-B
Catalog No. Product Name Information Selective / Pan IC50 / Ki
S3051 Bosentan Hydrate Bosentan (Ro 47-0203) is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively. Pan ET-B, Ki: 95 nM
S8051 Macitentan (ACT 064992) Macitentan (ACT 064992) is an orally active, non-peptide, dual ETA/ETB (endothelin) receptor antagonist with IC50 of 0.5 nM/391 nM. Pan ET-B, IC50: 391 nM