You can personalize your library with chemicals from within Selleck's inventory. Build the right library for your research endeavors by choosing from compounds in all of our available libraries.

Please contact us at [email protected] to customize your library.

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Specific Compounds Quantities 96 or 384 well Plate Map Dry/solid or DMSO solution

Antibodies

in vivo Antibodies

Biosimilar Antibodies

Bioreagents

qPCR: 2x SYBR Green qPCR Master Mix; 2x SYBR Green qPCR Master Mix(Low ROX); 2x SYBR Green qPCR Master Mix(High ROX)

Protein Assay: Protein A/G Magnetic Beads for IP; Anti-Flag magnetic beads; Anti-Flag Affinity Gel; Anti-Myc magnetic beads; Anti-HA magnetic beads; Poly FLAG Peptide lyophilized powder

Protease Inhibitor Cocktail: Protease Inhibitor Cocktail (EDTA-Free, 100X in DMSO); Phosphatase Inhibitor Cocktail (2 Tubes, 100X)

Cell Biology: Cell Counting Kit-8 (CCK-8)

Animal Experiment: Mouse Direct PCR Kit (For Genotyping)

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Catalog No.	Product Name	Information	Selective / Pan	IC50 / Ki
S7500	HJC0350	HJC0350 is a potent and selective EPAC2 inhibitor with IC50 of 0.3 μM, exhibiting no inhibition on Epac1.	Selective	EPAC2, IC50: 0.3 μM
S3382	ESI-05	ESI-05 (NSC 116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist with IC50 of 0.4 µM. ESI-05 (NSC 116966) inhibits cAMP-mediated activation of EPAC2 and EAPC2 mediated Rap1 activation.	Selective	EPAC2, IC50: 0.43 μM
S7499	ESI-09	ESI-09 is a specific exchange protein directly activated by cAMP (EPAC) inhibitor with IC50 of 3.2 μM and 1.4 μM for EPAC1 and EPAC2, respectively, >100-fold selectivity over PKA.	Pan	EPAC2, IC50: 1.4 μM
S0837	HJC0197	HJC0197 is a selective Epac 1/2 dual antagonists with an IC50 of 5.9 μM for Epac2.	Pan

EPAC2 Selective Inhibitors | Antagonists