Carbonic Anhydrase IV Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S1375 Dorzolamide HCl

Dorzolamide (MK-507, L-671152) HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent.

Pan Carbonic anhydrase IV, Ki: 31 nM
S4039 Methazolamide

Methazolamide (CL 8490) is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively.

Pan bCAIV, Ki: 36 nM