- Carbonic Anhydrase I
- Carbonic Anhydrase II
- Carbonic Anhydrase IV
- Carbonic Anhydrase IX
- Carbonic Anhydrase XII
Carbonic Anhydrase II Selective Inhibitors
|Catalog No.||Product Name||Information||Selective / Pan||IC50 / Ki|
Dorzolamide HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent.
|Selective||Carbonic anhydrase II, Ki: 1.9 nM|
Brinzolamide is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM.
|Selective||CAII, IC50: 3.19 nM|
Methazolamide is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively.
|Pan||hCAII, Ki: 14 nM|
U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM, respectively, very low inhibition for CA I and CA II.
|Pan||CAII, Ki: 9.64 μM|
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