CYP17 Selective Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S1123 Abiraterone

Abiraterone is a potent CYP17 inhibitor with IC50 of 2 nM.

Selective CYP17, IC50: 2 nM
S2246 Abiraterone Acetate

Abiraterone Acetate is an acetate salt form of Abiraterone which is a steroidal cytochrome CYP17 inhibitor with IC50 of 72 nM.

Selective CYP17, IC50: 72 nM
S2803 Galeterone

Galeterone is a selective CYP17 inhibitor and androgen receptor (AR) antagonist with IC50 of 300 nM and 384 nM, respectively, and is a potent inhibitor of human prostate tumor growth. Phase 2.

Selective CYP17, IC50: 300 nM