• CXCR1
  • CXCR2
  • CXCR4
  • CXCR3

CXCR3 Selective Antagonists

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S8682 AMG 487 AMG 487 is an orally active and selective CXC chemokine receptor 3 (CXCR3) antagonist that inhibits the binding of IP-10 (CXCL10) and ITAC (CXCL11) to CXCR3 with IC50 of 8.0 nM and 8.2 nM, respectively. Selective CXCR3-CXCL11, IC50: 8.2 nM; CXCR3-CXCL10, IC50: 8.0 nM