Home Metabolism Acetyl-CoA carboxylase ACC Selective Inhibitors

ACC Selective Inhibitors

  • ACC
  • ACC1
  • ACC2
Catalog No. Product Name Information Selective / Pan IC50 / Ki
S6145 PF-05221304 PF-05221304 is an orally bioavailable, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), an enzyme that catalyzes the first committed step in de novo lipogenesis (DNL). Selective
S6753 CP 640186 CP 640186 is an isozyme-nonselective ACC (Acetyl-CoA carboxylase) inhibitor with IC50 values of 53 and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2, respectively. Selective ACC, IC50: 55 nM