Prostaglandin E2 (PGE2)

Catalog No.S3003 Synonyms: Dinoprostone

For research use only.

Prostaglandin E2 (PGE2, Dinoprostone) palys important effects in labour (softens cervix and causes uterine contraction) and also stimulates osteoblasts to release factors that stimulate bone resorption by osteoclasts.

Prostaglandin E2 (PGE2) Chemical Structure

CAS No. 363-24-6

Selleck's Prostaglandin E2 (PGE2) has been cited by 13 publications

Purity & Quality Control

Choose Selective PGES Inhibitors

Biological Activity

Description Prostaglandin E2 (PGE2, Dinoprostone) palys important effects in labour (softens cervix and causes uterine contraction) and also stimulates osteoblasts to release factors that stimulate bone resorption by osteoclasts.
Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HeLa M4fuR2Z2dmO2aX;uJIF{e2G7 MVjUVH9VWkGQU2DPVnRGWjpidYD0ZYtmKGmwIGDHWE1mgHC{ZYPzbY5oKEinTHGgZ4VtdHNuIFvtJF0hOC5yOUSg{txONg>? NIf2R4I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi95N{W0N|Y6Lz55N{W0N|Y6RC:jPh?=
HeLa MnHwSpVv[3Srb36gZZN{[Xl? MkL6WHBgXFKDTmPQU3JVTVJ8IIXweIFs\SCrbjDQS3Qu\XiycnXzd4lv\yCKZVzhJINmdGy|LDDLNU8zKD1iMD6xJO69VS5? MkfxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwQDd6N{[3O{c,QDd6N{[3O|ww[T5?
S2 MYjGeY5kfGmxbjDhd5NigQ>? NIDnWHZVWF:WUlHOV3BQWlSHUkqgeZB1[WunIHnuJG9EXDJvZYjwdoV{e2mwZzDTNkBk\WyuczygT40hRSByLkCyPFkh|ryPLh?= NFfxfnI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUmwO|E5Pid-MUG5NFcyQDZ:L3G+
S2 MXXGeY5kfGmxbjDhd5NigQ>? NGrkWI5VWF:WUlHOV3BQWlSHUkqgeZB1[WunIHnuJG9CXDRvZYjwdoV{e2mwZzDTNkBk\WyuczygT40hRSByLkG1OEDPxE1w M1LqPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFzOUC3NVg3Lz5zMUmwO|E5PjxxYU6=
S2 MkXBSpVv[3Srb36gZZN{[Xl? MlfRWHBgXFKDTmPQU3JVTVJ8IIXweIFs\SCrbjDPRXQ{NWW6cILld5NqdmdiU{KgZ4VtdHNuIFvtJF0hOC5|NEWg{txONg>? NGjO[Yg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUmwO|E5Pid-MUG5NFcyQDZ:L3G+
S2 MmPpSpVv[3Srb36gZZN{[Xl? NXvlNYJtXFChVGLBUnNRV1KWRWK6JJVxfGGtZTDpckBQS1RzLXX4dJJme3OrbnegV|Ih[2WubIOsJGtuKD1iMD62OVch|ryPLh?= NIrwdHA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUmwO|E5Pid-MUG5NFcyQDZ:L3G+
S2 MlXTSpVv[3Srb36gZZN{[Xl? MYfUVH9VWkGQU2DPVnRGWjpidYD0ZYtmKGmwIF;BWFIu\XiycnXzd4lv\yCVMjDj[YxteyxiS32gQUAxNjdzMzFOwG0v NFPrZow9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUmwO|E5Pid-MUG5NFcyQDZ:L3G+
S2 NV;te29CTnWwY4Tpc44h[XO|YYm= Mof6WHBgXFKDTmPQU3JVTVJ8IIXweIFs\SCrbjDPRXQyNWW6cILld5NqdmdiU{KgZ4VtdHNuIFvtJF0hOC57NzFOwG0v MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOTlyN{G4Okc,OTF7MEexPFY9N2F-
HEK293 M322UWZ2dmO2aX;uJIF{e2G7 NH\hfIRKdmirYnn0c5J6KGGldHn2bZR6KGGpYXnud5QhcHWvYX6gSXA1KHKnY3XweI9zKGW6cILld5Nm\CCrbjDISWszQTNiZXLuZUBk\WyuczygTWM2OCB;IECuNFAxPyEQvF2u MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOjZ2M{myO{c,OTJ4NEO5Nlc9N2F-
HEK293 Moe1SpVv[3Srb36gZZN{[Xl? NYrLTI1OTVB2IHHnc45qe3RicH;0[Y5kgSC3dHnsbZpqdmdiYTDzeIFjdGViY3zvcoUhd2ZicGPWOFAuTVB2IITyZY5{\mWldHXkJIlvfG9iSFXLNlk{KGOnbHzzJIV5eHKnc4PpcochTVB2IILlZ4VxfG:{LDDFR|UxKD1iMD6wNFMh|ryPLh?= NXvJVXZyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUK2OFM6OjdpPkGyOlQ{QTJ5PD;hQi=>
Sf9 MWDGeY5kfGmxbjDhd5NigQ>? MUjUVH9VWkGQU2DPVnRGWjpidYD0ZYtmKCi4ZYPpZ4xmMSCrbjDt[Y1jemGwZTD2[ZNq[2ynczDmdo9uKE2UUESt[ZhxemW|c3nu[{BU\jliY3XscJMtKEuvIE2gN{41KM7:TT6= NET2SW89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMkizOVQyOid-MUK4N|U1OTJ:L3G+
HEK293 NUG1eml2TnWwY4Tpc44h[XO|YYm= MXrEbZNxdGGlZX3lcpQhd2ZiW{PIYXBITTJiZoLvcUBpfW2jbjDFVFMhemWlZYD0c5Ih\XiycnXzd4VlKGmwIFjFT|I6OyClZXzsd{whU2liPTCwMlAxODN|IN88UU4> M3HUUVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NUOxOFg5Lz5zN{WzNVQ5QDxxYU6=
HEK293 MXTGeY5kfGmxbjDhd5NigQ>? NV[3XGN3TGm|cHzhZ4Vu\W62IH;mJHs{UF2SR1WyJIZzd21iaIXtZY4hTVB2IILlZ4VxfG:{IHX4dJJme3OnZDDpckBJTUt{OUOgZ4VtdHNuIFvpJF0hOC5yMEC3PUDPxE1w Ml\xQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3M{G0PFgoRjF5NUOxOFg5RC:jPh?=
HEK293 NYL0O4MxTnWwY4Tpc44h[XO|YYm= MnOySIl{eGyjY3Xt[Y51KG:oIGuzTH1RT0V{IH\yc40hcHWvYX6gSXAzKHKnY3XweI9zKGW6cILld5Nm\CCrbjDISWszQTNiY3XscJMtKEurIE2gNE4xODR7IN88UU4> NX\kOYxJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe1N|E1QDhpPkG3OVMyPDh6PD;hQi=>
HEK293 MYDGeY5kfGmxbjDhd5NigQ>? MmX6SIl{eGyjY3Xt[Y51KG:oIGuzTH1RT0V{IH\yc40hcHWvYX6gSXAyKHKnY3XweI9zKGW6cILld5Nm\CCrbjDISWszQTNiY3XscJMtKEurIE2gNE4xODlzIN88UU4> NXnW[2l7RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe1N|E1QDhpPkG3OVMyPDh6PD;hQi=>
HEK293 M{jCR2Z2dmO2aX;uJIF{e2G7 M2i5V2Fod26rc4SgZYN1cX[rdImgZYdicW6|dDDyZZQhTVB{IILlZ4VxfG:{IHX4dJJme3OnZDDpckBJTUt{OUOgZ4VtdHNiYYPz[ZN{\WRiYYOgd5RqdXWuYYTpc44hd2ZiY1HNVEBz\WynYYPlMEBGSzVyIE2gNE4xODB{IN88UU4> M2\UXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkWwPFI{Lz5zOUK1NFgzOzxxYU6=
HEK293 NGm4fmRHfW6ldHnvckBie3OjeR?= M3jIbmFod26rc4SgZYN1cX[rdImgZYdicW6|dDDyZZQhTVB2IILlZ4VxfG:{IHX4dJJme3OnZDDpckBJTUt{OUOgZ4VtdHNiYYPz[ZN{\WRiYYOgd5RqdXWuYYTpc44hd2ZiY1HNVEBz\WynYYPlMEBGSzVyIE2gNE4xODB5IN88UU4> M4XxdlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkWwPFI{Lz5zOUK1NFgzOzxxYU6=
HEK293 MXfGeY5kfGmxbjDhd5NigQ>? MnnXTY5pcWKrdHnvckBw\iC{YYSgSXA1KHKnY3XweI9zKGW6cILld5Nm\CCrbjDISWszQTNiY3XscJMtKEmFNUCgQUAxNjByMkGg{txONg>? NU\HcVBsRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyOVA5OjNpPkG5NlUxQDJ|PD;hQi=>
HEK293 M{\MNmZ2dmO2aX;uJIF{e2G7 MVnJcohq[mm2aX;uJI9nKHKjdDDFVFIhemWlZYD0c5Ih\XiycnXzd4VlKGmwIFjFT|I6OyClZXzsd{whUUN3MDC9JFAvODB3MjFOwG0v MnfVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{NUC4NlMoRjF7MkWwPFI{RC:jPh?=
CHO MUTGeY5kfGmxbjDhd5NigQ>? Mmj4OlAhdWmwcx?= M4m5U2Rqe3CuYXPlcYVvfCCxZjDbN2heNVCJRUKg[pJwdSCvb4Xz[UBGWDRicnXj[ZB1d3JiZYjwdoV{e2WmIHnuJGNJVyClZXzsd{Bi\nSncjC2NEBucW6|IHL5JIxqeXWrZDDzZ4lvfGmubHH0bY9vKGOxdX70bY5oNCCNaTC9JFAvODB|MTFOwG0v MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjFzOUS3NUc,OjJzMUm0O|E9N2F-
CHO NV61PJo5TnWwY4Tpc44h[XO|YYm= M2TUdVYxKG2rboO= M{LuNGRqe3CuYXPlcYVvfCCxZjDbN2heNVCJRUKg[pJwdSCvb4Xz[UBGWDNicnXj[ZB1d3JiZYjwdoV{e2WmIHnuJGNJVyClZXzsd{Bi\nSncjC2NEBucW6|IHL5JIxqeXWrZDDzZ4lvfGmubHH0bY9vKGOxdX70bY5oNCCNaTC9JFAvODB3IN88UU4> MmfrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzMUm0O|EoRjJ{MUG5OFcyRC:jPh?=
CHO MkXVSpVv[3Srb36gZZN{[Xl? MlXSNlAhdWmwcx?= M1;RTWRqe3CuYXPlcYVvfCCxZjDbN2heNVCJRUKg[pJwdSCvb4Xz[UBGWDFicnXj[ZB1d3JiZYjwdoV{e2WmIHnuJGNJVyClZXzsd{Bi\nSncjCyNEBucW6|IHL5JIxqeXWrZDDzZ4lvfGmubHH0bY9vKGOxdX70bY5oNCCNaTC9JFAvODB4IN88UU4> MlewQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzMUm0O|EoRjJ{MUG5OFcyRC:jPh?=
CHO MofwSpVv[3Srb36gZZN{[Xl? M1fESVYxKG2rboO= M1\ETWRqe3CuYXPlcYVvfCCxZjDbN2heNVCJRUKg[pJwdSCvb4Xz[UBGWDJicnXj[ZB1d3JiZYjwdoV{e2WmIHnuJGNJVyClZXzsd{Bi\nSncjC2NEBucW6|IHL5JIxqeXWrZDDzZ4lvfGmubHH0bY9vKGOxdX70bY5oNCCNaTC9JFAvODJ{IN88UU4> M{PFNFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MUG5OFcyLz5{MkGxPVQ4OTxxYU6=
CHO MlTpSpVv[3Srb36gZZN{[Xl? NVf6cWdHPjBibXnudy=> M3vpd2Rqe3CuYXPlcYVvfCCxZjDbN2heNVCJRUKg[pJwdSCvb4Xz[UBGWDRicnXj[ZB1d3JiZYjwdoV{e2WmIHnuJGNJVyClZXzsd{Bi\nSncjC2NEBucW6|IHL5JJNkcW62aXzsZZRqd25iY3;1cpRqdmduIFvpJF0hOC5yMEOxJO69VS5? NXjTU|ZoRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKzPFY6PzlpPkKyN|g3QTd7PD;hQi=>
CHO MnXISpVv[3Srb36gZZN{[Xl? MnPGOlAhdWmwcx?= MnPWSIl{eGyjY3Xt[Y51KG:oIGuzTH0uWEeHMjDmdo9uKG2xdYPlJGVROyC{ZXPldJRweiCneIDy[ZN{\WRiaX6gR2hQKGOnbHzzJIFnfGW{IE[wJI1qdnNiYomgd4NqdnSrbHzheIlwdiClb4XueIlv\yxiS3mgQUAxNjByNTFOwG0v MonvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ|OE[5O|koRjJ{M{i2PVc6RC:jPh?=
CHO MoLzSpVv[3Srb36gZZN{[Xl? M{nKW|YxKG2rboO= NIfvOHdFcXOybHHj[Y1mdnRib3[gX|NJZS2SR1WyJIZzd21ibX;1d4UhTVBzIILlZ4VxfG:{IHX4dJJme3OnZDDpckBEUE9iY3XscJMh[W[2ZYKgOlAhdWmwczDifUB{[2mwdHnscIF1cW:wIHPveY51cW6pLDDLbUA:KDBwMEC2JO69VS5? M4nqdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{M{i2PVc6Lz5{MkO4Olk4QTxxYU6=
CHO NUDublJkTnWwY4Tpc44h[XO|YYm= M3;QXFYxKG2rboO= Mki1SIl{eGyjY3Xt[Y51KG:oIGuzTH0uWEeHMjDmdo9uKG2xdYPlJGVROiC{ZXPldJRweiCneIDy[ZN{\WRiaX6gR2hQKGOnbHzzJIFnfGW{IE[wJI1qdnNiYomgd4NqdnSrbHzheIlwdiClb4XueIlv\yxiS3mgQUAxNjB{MjFOwG0v NHfRT5k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkO4Olk4QSd-MkKzPFY6Pzl:L3G+
CHEM1 MVvGeY5kfGmxbjDhd5NigQ>? NIPjdG8zKGi{cx?= MkfMSIl{eGyjY3Xt[Y51KG:oIGuzTH1RT0V{IH\yc40hcHWvYX6gdoVkd22kaX7hcpQheHKxc4Thco9q\CCHUESgdoVk\XC2b4KgbY4hS0iHTUGgZ4VtdHNiYX\0[ZIhOiCqcoOsJGtqKD1iMD6wNFA1PSEQvF2u MlraQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN2MEOwPFIoRjJ|NECzNFgzRC:jPh?=
CHEM1 M3rNTWZ2dmO2aX;uJIF{e2G7 NIj1OHEzKGi{cx?= M4DUNmRqe3CuYXPlcYVvfCCxZjDbN2heWEeHMjDmdo9uKGi3bXHuJJJm[2:vYnnuZY51KHC{b4P0ZY5wcWRiRWC0JJJm[2WydH;yJIlvKEOKRV2xJINmdGy|IHHmeIVzKDJiaILzMEBKSzVyIE2gNE4xODFzIN88UU4> MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzRyM{C4Nkc,OjN2MEOwPFI9N2F-
CHO MkjTSpVv[3Srb36gZZN{[Xl? MXKxNFAhdk1? NY\WT2lzSWO2aY\peJkh[XRicnXjc41jcW6jboSgSXAyKHKnY3XweI9zKCi3bnvuc5dvKG:{aXfpckkh\XiycnXzd4VlKGmwIFPIU{Bk\WyuczDjc{1mgHC{ZYPzbY5oKEezIIDyc5RmcW5iYYSgNVAxKG6PIHL5JIVt\WO2cnnjZYwh[2WubDDzeYJ{fHKjdHWgbY1x\WSjbnPlJJNmdnOrbnegd5l{fGWv NHf5ZlE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUewNVI2PCd-MkW3NFEzPTR:L3G+
CHO MoTVSpVv[3Srb36gZZN{[Xl? NGT6WFAyODBibl2= MX\BZ5Rqfmm2eTDheEBz\WOxbXLpcoFvfCCHUESgdoVk\XC2b4KgLJVvc26xd36gc5Jq\2mwKTDlfJBz\XO|ZXSgbY4hS0iRIHPlcIx{KGOxLXX4dJJme3OrbnegS5MheHKxdHXpckBifCBzMECgcm0h[nliZXzlZ5RzcWOjbDDj[YxtKHO3YoP0doF1\SCrbYDl[IFv[2Vic3Xud4lv\yC|eYP0[Y0> Mk\FQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV5MEGyOVQoRjJ3N{CxNlU1RC:jPh?=
CHO MUHGeY5kfGmxbjDhd5NigQ>? NFrIbmYyODBibl2= NHm2TGRC[3Srdnn0fUBifCC{ZXPvcYJqdmGwdDDFVFMhemWlZYD0c5IhMHWwa37ve44hd3KrZ3nuLUBmgHC{ZYPz[YQhcW5iQ1jPJINmdGy|IHPvMYV5eHKnc4PpcochT2licILveIVqdiCjdDCxNFAhdk1iYomg[Yxm[3S{aXPhcEBk\WyuIIP1ZpN1emG2ZTDpcZBm\GGwY3Wgd4Vve2mwZzDzfZN1\W1? NEnNOoo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUewNVI2PCd-MkW3NFEzPTR:L3G+
CHO MljHSpVv[3Srb36gZZN{[Xl? M{jUeFMxKG2rboO= M13UU2Fod26rc4SgZYN1cX[rdImgZZQhcHWvYX6gSXAzKHKnY3XweI9zKGW6cILld5Nm\CCrbjDDTG8h[2WubIOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5iaX70doFk\WyudXzhdkBkSU2SIHzleoVtKGGodHXyJFMxKG2rboOgZpkhUFSURjDt[ZRpd2RuIFXDOVAhRSByLkCwNVkh|ryPLh?= MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjl6NUOyNEc,OjZ7OEWzNlA9N2F-
CHO NVqwVlJyTnWwY4Tpc44h[XO|YYm= NGnPdmVC\2:waYP0JIFkfGm4aYT5JIF1KGi3bXHuJGVROyC{ZXPldJRweiCneIDy[ZN{\WRiaX6gR2hQKGOnbHzzJIF{e2W|c3XkJIF{KGmwY4LlZZNmKGmwIHnueJJi[2WubIXsZZIh[2GuY3n1cUBt\X[nbDDifUBndHWxcnXzZ4Vv[2ViYnHz[YQh[W6jbInzbZMtKEWFNUCgQUAxNjByMkWg{txONg>? M{ezdVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4OUi1N|IxLz5{Nkm4OVMzODxxYU6=
CHO MWLGeY5kfGmxbjDhd5NigQ>? MWnB[49vcXO2IHHjeIl3cXS7IHH0JIh2dWGwIFXQNUBz\WOncITvdkBmgHC{ZYPz[YQhcW5iQ1jPJINmdGy|IHHzd4V{e2WmIHHzJIlv[3KnYYPlJIlvKGmwdILhZ4VtdHWuYYKgZ4Ft[2m3bTDs[ZZmdCCkeTDmcJVwemW|Y3XuZ4Uh[mG|ZXSgZY5idHm|aYOsJGVEPTBiPTCwMlAxOzdizszNMi=> MkO2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ7OEWzNlAoRjJ4OUi1N|IxRC:jPh?=
CHO MkTPSpVv[3Srb36gZZN{[Xl? NH;tcJk{OCCvaX7z NVrVcIhbSWexbnnzeEBi[3Srdnn0fUBifCCqdX3hckBGWDRicnXj[ZB1d3JiZYjwdoV{e2WmIHnuJGNJVyClZXzsd{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDpcpRz[WOnbHz1cIFzKGODTWCgcIV3\WxiYX\0[ZIhOzBibXnud{BjgSCKVGLGJI1mfGixZDygSWM2OCB;IECuNFA4PSEQvF2u NUXvZZJ4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[5PFU{OjBpPkK2PVg2OzJyPD;hQi=>
Chem1 MU\GeY5kfGmxbjDhd5NigQ>? M4mxOWFod26rc4SgZYN1cX[rdImgZZQhcHWvYX6gSnAhemWlZYD0c5Ih\XiycnXzd4VlKGmwIHj1cYFvKEOqZX2xJINmdGy|IHHzd4V{e2WmIHHzJIlv[3KnYYPlJIlvKGmwdILhZ4VtdHWuYYKgZ4Ft[2m3bTDs[ZZmdCCkeTDmcJVwemW|Y3XuZ4Uh[mG|ZXSgZY5idHm|aYOsJGVEPTBiPTCwMlI2KM7:TT6= NVLZOHVlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[5PFU{OjBpPkK2PVg2OzJyPD;hQi=>
HEK293 MYDGeY5kfGmxbjDhd5NigQ>? MYO5NEBucW6| NXj5OGp5SWexbnnzeEBi[3Srdnn0fUBifCCSS{KteIFo\2WmIHj1cYFvKEWSMjDy[YNmeHSxcjDlfJBz\XO|ZXSgbY4hUEWNMkmzJINmdGy|IHHzd4V{e2WmIHHzJIlv\HWldHnvckBw\iCHQT30ZYdo\WRiYnX0ZU1ienKnc4TpckBz\WO{dXn0cYVvfCCrbnP1ZoF1\WRiZn;yJFkxKG2rboOgZpkh[mW2YT3nZYxi[3Sxc3nkZZNmKHKncH;yeIVzKGenbnWgZZN{[XluIFXDOVAhRSByLkO0OkDPxE1w MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjl6NUOyNEc,OjZ7OEWzNlA9N2F-
CHO NH3q[4VHfW6ldHnvckBie3OjeR?= MkL3N|AhdWmwcx?= MVnB[49vcXO2IHHjeIl3cXS7IHH0JIh2dWGwIFnQJJJm[2WydH;yJIV5eHKnc4Pl[EBqdiCFSF:gZ4VtdHNiYYPz[ZN{\WRiYYOgbY5kemWjc3WgbY4hcW62cnHj[YxtfWyjcjDjRW1RKGyndnXsJIFnfGW{IEOwJI1qdnNiYomgTHRTTiCvZYToc4QtKEWFNUCgQUAxNjN2NzFOwG0v MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjl6NUOyNEc,OjZ7OEWzNlA9N2F-
HEK293 NEnqT5FHfW6ldHnvckBie3OjeR?= NF3mWXFFcXOybHHj[Y1mdnRib3[gX|NJZVCJRUKg[pJwdSCqdX3hckBz\WOxbXLpcoFvfCCycn;zeIFvd2mmIFXQNkBz\WOncITvdkBmgHC{ZYPz[YQhcW5iSFXLNlk{KGOnbHzzMEBKSzVyIE2gNE4xODJ4IN88UU4> MkXqQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ7OEi4NFEoRjJ4OUi4PFAyRC:jPh?=
HEK293 MoL2SpVv[3Srb36gZZN{[Xl? M3nzd|EzOCCvaX7z NGTFOYpFcXOybHHj[Y1mdnRib3[gX|NJZVCJRUKg[pJwdSCqdX3hckBz\WOxbXLpcoFvfCCHUESgdoVk\XC2b4Kg[ZhxemW|c3XkJIlvKEiHS{K5N{Bk\WyuczDt[YF{fXKnZDDh[pRmeiBzMkCgcYlveyCkeTDzZ4lvfGmubHH0bY9vKGOxdX70bY5oKG2ndHjv[EwhUUN3MDC9JFAvODByNUWg{txONg>? M4naWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5OEe2NlUxLz5{N{i3OlI2ODxxYU6=
HEK293 NInJVHBHfW6ldHnvckBie3OjeR?= Ml7TNVIxKG2rboO= NXzROnlbTGm|cHzhZ4Vu\W62IH;mJHs{UF2SR1WyJIZzd21iaIXtZY4hemWlb33ibY5idnRiRWCyJJJm[2WydH;yJIV5eHKnc4Pl[EBqdiCKRVuyPVMh[2WubIOgcYVie3W{ZXSgZYZ1\XJiMUKwJI1qdnNiYomgd4NqdnSrbHzheIlwdiClb4XueIlv\yCvZYToc4QtKEmFNUCgQUAxNjByMk[g{txONg>? MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzh5NkK1NEc,Ojd6N{[yOVA9N2F-

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 352.47
Formula

C20H32O5

CAS No. 363-24-6
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CCCCCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)O)O)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05412810 Not yet recruiting -- Mechanical Ventilation Complication|Hyperoxia Ohio State University May 31 2022 --
NCT04456569 Recruiting Device: Geniculate Artery Embolization Osteo Arthritis Knee|Arthritis|Osteoarthritis|Osteoarthritis Knee University of Minnesota February 1 2022 Not Applicable
NCT04626609 Recruiting Other: Biopsy samples|Other: Blood samples Eosinophilic Esophagitis (EoE) Medical University of Graz July 1 2021 --
NCT04786548 Recruiting Drug: Celecoxib Obsessive-Compulsive Disorder New York State Psychiatric Institute April 1 2021 Phase 2

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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