Prednisolone Acetate

Synonyms: Omnipred,Prednisolone-21-acetate

Prednisolone Acetate (Omnipred,Prednisolone-21-acetate) is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant agent.

Prednisolone Acetate  Chemical Structure

Prednisolone Acetate Chemical Structure

CAS: 52-21-1

Selleck's Prednisolone Acetate has been cited by 5 publications

Purity & Quality Control

Batch: Purity: 99.37%
99.37

Prednisolone Acetate Related Products

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Biological Activity

Description Prednisolone Acetate (Omnipred,Prednisolone-21-acetate) is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant agent.
Targets
Glucocorticoid receptor [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06119529 Recruiting
Healthy|Atopic Dermatitis
Eli Lilly and Company
November 1 2023 Phase 1
NCT05986422 Recruiting
Post-COVID-19 Syndrome
Charite University Berlin Germany
October 1 2023 Phase 2
NCT06066814 Not yet recruiting
Acute on Chronic Liver Failure
Institute of Liver and Biliary Sciences India
October 7 2023 --
NCT05984381 Recruiting
Bullous Pemphigoid
All India Institute of Medical Sciences Bhubaneswar
August 1 2023 Phase 4

Chemical Information & Solubility

Molecular Weight 402.48 Formula

C23H30O6

CAS No. 52-21-1 SDF Download Prednisolone Acetate SDF
Smiles CC(=O)OCC(=O)C1(CCC2C1(CC(C3C2CCC4=CC(=O)C=CC34C)O)C)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 81 mg/mL ( (201.25 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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