Prednisolone Acetate

Catalog No.S2570 Synonyms: Omnipred

For research use only.

Prednisolone Acetate (Omnipred) is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant agent.

Prednisolone Acetate  Chemical Structure

CAS No. 52-21-1

Selleck's Prednisolone Acetate has been cited by 4 Publications

Purity & Quality Control

Choose Selective Glucocorticoid Receptor Inhibitors

Biological Activity

Description Prednisolone Acetate (Omnipred) is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant agent.
Targets
Glucocorticoid receptor [1]

Protocol (from reference)

Solubility (25°C)

In vitro

In vivo

Add solvents to the product individually and in order
(Data is from Selleck tests instead of citations):
2% DMSO+30% PEG 300+2% Tween 80+ddH2O
For best results, use promptly after mixing.

5mg/mL

Chemical Information

Molecular Weight 402.48
Formula

C23H30O6

CAS No. 52-21-1
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC(=O)OCC(=O)C1(CCC2C1(CC(C3C2CCC4=CC(=O)C=CC34C)O)C)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04560582 Not yet recruiting Procedure: Blood Draw Kidney Transplant; Complications|Kidney Transplant Rejection|Kidney Transplant Failure University of Minnesota August 31 2022 --
NCT05341401 Not yet recruiting Drug: Budesonide MMX|Drug: Prednisolone Ulcerative Colitis Chronic Assiut University June 2022 Phase 2|Phase 3
NCT05435781 Recruiting Drug: Hydrocortisone|Drug: Placebo for hydrocortisone Adrenal Insufficiency|Polymyalgia Rheumatica|Giant Cell Arteritis Ulla Feldt-Rasmussen|Aarhus University Hospital|Odense University Hospital|Rigshospitalet Denmark June 7 2022 Phase 4
NCT05417906 Recruiting Other: Standard care|Other: Eosinophil-directed care Asthma Attack|Asthma Changi General Hospital|Singapore General Hospital June 2022 Phase 2
NCT04965636 Not yet recruiting Drug: Mepolizumab Hypereosinophilic Syndrome GlaxoSmithKline June 30 2022 Phase 3

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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