Betamethasone Dipropionate

Catalog No.S1688 Synonyms: SCH 11460

For research use only.

Betamethasone Dipropionate (SCH 11460) is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.

Betamethasone Dipropionate Chemical Structure

CAS No. 5593-20-4

Purity & Quality Control

Choose Selective Glucocorticoid Receptor Inhibitors

Biological Activity

Description Betamethasone Dipropionate (SCH 11460) is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.
Glucocorticoid receptor [1]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 504.59


CAS No. 5593-20-4
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)OC(=O)CC

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03476746 Completed Drug: LEO 90100 foam|Drug: Dovobet® ointment Healthy LEO Pharma March 20 2018 Phase 1
NCT03462927 Completed Drug: MC2-01 Cream|Drug: CAL/BDP combination Psoriasis Vulgaris MC2 Therapeutics February 8 2018 Phase 2
NCT02605057 Completed Drug: LEO 80185 gel|Drug: Dovobet(r) Ointment Psoriasis Vulgaris LEO Pharma November 2015 Phase 1
NCT01768013 Completed Drug: LEO 90105 Psoriasis Vulgaris LEO Pharma July 2012 Phase 1|Phase 2
NCT00279162 Completed Drug: Calcipotriene/betamethasone gel and ointment Psoriasis LEO Pharma December 2005 Phase 3

(data from, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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