Albendazole (SKF-62979)

Catalog No.S1640

For research use only.

Albendazole (SKF-62979) is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations.

Albendazole (SKF-62979) Chemical Structure

CAS No. 54965-21-8

Selleck's Albendazole (SKF-62979) has been cited by 8 Publications

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Purity & Quality Control

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Biological Activity

Description Albendazole (SKF-62979) is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations.
tubulin [1]
In vitro

Albendazole is reported to be teratogenic in rats, and is extensively metabolized to the sulfoxide derivative. Albendazole and its sulfoxide metabolite elicit an accumulation of cells in the mitotic phase of the cell cycle. [1]

In vivo Albendazole causes an induction of hepatic activities of CYP1A1-associated ethoxyresorufin O-deethylase (EROD) 65 fold, CYP1A2-associated methoxyresorufin O-demethylase (MROD) 6 fold, CYP2B1-associated penthoxyresorufin O-dealkylase (PROD) 4 fold, CYP2B2-associated benzyloxyresorufin O-dealkylase (BROD) 14 fold, as well as a partial reduction of CYP2E1-associated 4-nitrophenol hydroxylase (4-NPH) activity in the rat. [2] Albendazole is metabolized to its pharmacologically active sulfoxide metabolites by liver and lung microsomes from sheep and cattle, as well as by cattle intestinal microsomes. [3] Albendazole (ABZ) is a benzimidazole derivative with a broad spectrum of activity against human and animal helminthe parasites. [4] Albendazole and its metabolites are extensively distributed to the digestive tract, mainly into the abomasal fluid, after the i.v. and i.r. administrations. Albendazole and its active albendazole sulphoxide (ABZSO) metabolite are recovered in tapeworms collected from both i.v. and i.r. treated lambs. [5]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 265.33


CAS No. 54965-21-8
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CCCSC1=CC2=C(C=C1)N=C(N2)NC(=O)OC

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03527745 Completed Drug: Albendazole|Drug: Placebo Trichuriasis|Hookworm Infections Jennifer Keiser|Centre Suisse de Recherches Scientifiques en Cote d''Ivoire|Swiss Tropical & Public Health Institute October 23 2018 Phase 2

(data from, updated on 2022-01-17)

Tech Support

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