New TLR Inhibitors

Cat.No. Product Name Information
S8531 PF-06650833 PF-06650833 is a potent, selective inhibitor of IRAK4 with an IC50 of 0.2 nM.
S6719 E6446 (dihydrochloride) E6446 is a specific Toll-like receptor 9 inhibitor.
S7455 Resatorvid (TAK-242) Resatorvid (TAK-242) is a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, blocking LPS-induced production of NO, TNF-α, IL-6, and IL-1β in macrophages with IC50 values of 1-11 nM.
S6573 MD2-IN-1 MD2-IN-1 is an inhibitor of Myeloid differentiation protein 2 (MD2) with a KD value of 189 μM.
All TLR Inhibitors