New TLR Inhibitors

Cat.No. Product Name Information
S8838 LHC165 LHC165 is a TLR7 agonist designed for localized intratumoral therapies.
S6598 IRAK-1-4 Inhibitor I IRAK-1-4 Inhibitor I is an inhibitor of interleukin-1 receptor associated kinase (IRAK) with IC50 values of 0.3 μM and 0.2 μM for IRAK-1 and IRAK-4, respectively. It displays IC50 values >10 µM in a panel of 27 other kinases tested.
S6719 E6446 (dihydrochloride)) E6446 is a specific Toll-like receptor 9 inhibitor.
S7455 Resatorvid (TAK-242) Resatorvid (TAK-242) is a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, blocking LPS-induced production of NO, TNF-α, IL-6, and IL-1β in macrophages with IC50 values of 1-11 nM.
All TLR Inhibitors