New Prostaglandin Receptor Inhibitors

Cat.No. Product Name Information
S6793 TG4-155 TG4-155 is a potent and selective Prostaglandin Receptor EP2(PTGER2) antagonist with Ki value of 9.9 nM.
S6694 Grapiprant (CJ-023423) Grapiprant is the first EP4 receptor-specific antagonist approved by FDA for control of pain and inflammation in dogs with osteoarthritis. Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor in a concentration-dependent manner with an IC50 value of 35 nM and with a Ki value of 24 nM.
S6649 E7046(ER-886406) E7046 is a selective inhibitor of the prostaglandin E2 (PGE2) receptor EP4 with IC50 of 13.5 nM and Ki of 23.14 nM.
All Prostaglandin Receptor Inhibitors