HomeNew Prostaglandin Receptor Inhibitors

New Prostaglandin Receptor Inhibitors

Catalog No. Product Name Information
E2146 Iloprost Iloprost(Ciloprost, ZK 36374, Ventavis) is a prostacyclin (PGI2) analogue and is a potent agonist of the prostacyclin IP receptor and the prostaglandin E2 (PGE2) receptor subtype EP1. It exhibits high binding affinity for EP1 and IP receptors with Ki values of 1.1 nM and 3.9 nM, respectively.
E4846 Treprostinil Treprostinil is a potent agonist of DP1 and EP2  with EC50 of 0.6 nM and 6.2 nM for DP1 and EP2 receptors, respectively. It is a vasodilator used to treat pulmonary arterial hypertension and improves mitochondrial impairment in vitro.
≡ All Prostaglandin Receptor Inhibitors