New Autophagy Modulators

Catalog No. Product Name Information
E8307 Chloroquine dihydrochloride Chloroquine dihydrochloride acts as an inhibitor of autophagy and toll-like receptors (TLRs). Chloroquine dihydrochloride is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis.
E5898 SKLB-D18 SKLB-D18 is a first-in-class, potent, and selective inhibitor of ERK1/2 and ERK5 with an IC50's of 38.69 nM, 40.12 nM, and 59.72 nM, respectively, that also acts as an agonist of autophagy. It modulates mTOR/p70S6K and NCOA4-mediated ferroptosis, showing strong anti-tumor activity and offering a promising monotherapy strategy to overcome resistance in ERK1/2-targeted therapy for triple-negative breast cancer (TNBC).
F2724 Anti-SNAP29 Rabbit Antibody [P6H21]
F2531 Anti-SQSTM1/p62 Mouse Antibody [E23B2] p62 (Sequestosome-1),p62 Ick ligand,p62/SQSTM1,SQSTM1,SQSTM1 / p62,SQSTM1/p62
F1488 Anti-TMEM49/VMP1 Rabbit Antibody [J17M11]
All Autophagy Modulators