| Cat.No. |
Product Name |
Information |
|
S8954
|
STING agonist-1 (G10) |
STING agonist-1 (G10) is a novel human-specific STING agonist that triggers IFN regulatory factor 3 (IRF3)/ type I interferon (IFN)-associated transcription in human fibroblasts. STING agonist-1 (G10) potently reduces growth of Chikungunya virus (CHIKV) with IC90 of 8.01 μM and blocks replication of Alphavirus species Venezuelan Equine Encephalitis Virus (VEEV) with IC90 of 24.57 μM. |
|
S7904
|
2',3'-cGAMP |
2',3'-cGAMP is produced in response to DNA in the cytoplasm in mammalian cells and binds STING with high affinity and is an effective inducer of interferon-β (IFNβ). The binding affinity of 2 ’, 3’-cGAMP to STING is 3.79 nM (Kd value). |
|
S7905
|
3',3'-cGAMP |
3',3'-cGAMP activates the endoplasmic reticulum (ER)-resident receptor STING, thereby inducing an antiviral state and the secretion of type I IFNs. |
|
S6667
|
STING inhibitor C-178 |
C-178 is a covalent inhibitor of STING,covalently bind to Cys91. |
|
S6652
|
H-151 |
H-151 is a highly potent and covalent antagonist of STING that has noteworthy inhibitory activity both in human cells and in vivo. |
| ≡ All STING Inhibitors |
