| Cat.No. |
Product Name |
Information |
|
S6541
|
MTX-211 |
MTX-211 is a first-in-class dual inhibitor of PI3K and EGFR kinase. |
|
S6516
|
GNE-477 |
GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with an IC50 of 4 nM for PI3Kα and Kiapp of 21 nM for mTOR. |
|
S8693
|
Selective PI3Kδ Inhibitor 1 (compound 7n) |
Selective PI3Kδ Inhibitor 1 (compound 7n) is an inhibitor of PI3Kδ with an IC50 of 0.9 nM and >1000-fold selectivity against other class I PI3K isoforms [PI3K α/γ/β=3670/1460/21300 nM]. |
|
S5818
|
acalisib (GS-9820) |
acalisib (GS-9820) is a highly selective and potent p110δ inhibitor (IC50 = 14 nM) with 114- to 400-fold selectivity over the other class I PI3K enzymes and no activity against Class II and III PI3K family members or other PI3K-related proteins including mTOR and DNA-PK. |
| ≡ All PI3K Inhibitors |
