HomeNew Estrogen/progestogen Receptor Chemicals

New Estrogen/progestogen Receptor Chemicals

Catalog No. Product Name Information
F3358 Phospho-Estrogen Receptor α (Ser118) Rabbit mAb Estrogen Receptor alpha (phospho S118),Phospho-Estrogen Receptor α (Ser118)
S8986 Giredestrant Giredestrant (GDC-9545; RG6171) is an efficient and potent selective estrogen receptor degrader and a full antagonist with an IC50 of 0.05 nM in T-47D wild-type cells. It also exhibits anti-proliferative activity.
E4621 BHPI BHPI is a potent noncompetitive inhibitor of estrogen receptor α (ERα), which disrupts the protective estrogen–ERα-mediated activation of the unfolded protein response (UPR), leading to sustained UPR activation. It specifically inhibits the growth of drug-resistant ERα-positive breast and ovarian cancer cells and induces significant tumor regression in a mouse xenograft model of breast cancer.
F1063 Estrogen Receptor α Mouse mAb Estrogen Receptor alpha,Estrogen Receptor α
E1301 Imlunestrant Imlunestrant(LY3484356) is a potent, orally bioavailable selective estrogen receptor degrader (SERD) that functions as a pure antagonist of estrogen receptor alpha (ERα). It inhibits ER-dependent gene transcription and cell proliferation, resulting in sustained suppression of estrogen-driven growth in ER-positive cells.
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