New EGFR Inhibitors

Catalog No.	Product Name	Information
E1844	STX-721	STX-721(Elticertinib) is an irreversible inhibitor of EGFR harboring exon 20 insertion (ex20ins) mutations that selectively inhibits the proliferation of Ba/F3 cells expressing EGFR exon20 A769_V770insASV and D770_N771insSVD with an IC50 of 5.4 and 5.8 nM, respectively.
E6528	BBT-176	BBT-176 is a first-in-class reversible fourth-generation EGFR TKI with potent activity against osimertinib-resistant mutations with an IC50 of 49 nM (Del19/T790M/C797S), 202 nM (L858R/T790M/C797S), 42 nM (Del19/C797S), and 183 nM (L858R/C797S) in Ba/F3 cells.
≡ All EGFR Inhibitors