New EGFR Inhibitors

Cat.No. Product Name Information
S6546 PD153035 PD153035 is a specific and potent inhibitor of the epidermal growth factor (EGF) receptor tyrosine kinase (Ki = 5.2 pM).
S6541 MTX-211 MTX-211 is a first-in-class dual inhibitor of PI3K and EGFR kinase.
S6509 AG 494 AG-494, a member of the tyrphostin family of tyrosine kinase inhibitors, is a potent inhibitor of EGF receptor autophosphorylation (IC50=1.2 μM) and EGF-dependent cell growth (IC50=6 μM).
S6523 RG14620 RG14620, an EGFR inhibitor of the tyrphostin family, directly inhibits the transport function of ABCG2.
S6525 AG 555 AG-555 is an inhibitor of tyrosine kinase, interacts directly with topoisomerase I, thus preventing DNA relaxation. It inhibits EGFR with an IC50 of 0.7 μM.
≡ All EGFR Inhibitors