HomeNew P450 (e.g. CYP17) Inhibitors

New P450 (e.g. CYP17) Inhibitors

Catalog No. Product Name Information
E6401 Vicadrostat Vicadrostat (compound 29 A) is a potent and selective inhibitor of aldosterone synthase(CYP11B2) with an IC50 of 16 nM. It exhibits potential in renal disease, diabetic nephropathy, cardiovascular diseases and fibrotic disorder research.
E1816 Lorundrostat Lorundrostat (MT-4129) is a highly selective inhibitor of CYP11B2 (aldosterone synthase), with inhibition constant (Ki) values of 1.27 nM for hCYP11B2 and 475 nM for hCYP11B1. It demonstrates potential as a safe and effective treatment for aldosterone-dependent uncontrolled hypertension, including cases of treatment-resistant hypertension.
≡ All P450 (e.g. CYP17) Inhibitors