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Catalog No. Product Name Information Product Use Citations Product Validations
S3639 Tacrine hydrochloride hydrate Tacrine (Tetrahydroaminacrine, Tetrahydroaminoacridine) is a centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. It also acts as a histamine N-methyltransferase inhibitor.
S4589 Amodiaquine dihydrochloride dihydrate Amodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase with estimated Ki of 18.6 nM. It is also used as an antimalarial and anti-inflammatory agent.
Nat Biomed Eng, 2021, 10.1038/s41551-021-00718-9
J Med Chem, 2020, 31
bioRxiv, 2020, 10.1101/2020.04.13.039917
S3639 Tacrine hydrochloride hydrate Tacrine (Tetrahydroaminacrine, Tetrahydroaminoacridine) is a centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. It also acts as a histamine N-methyltransferase inhibitor.
S4589 Amodiaquine dihydrochloride dihydrate Amodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase with estimated Ki of 18.6 nM. It is also used as an antimalarial and anti-inflammatory agent.
Nat Biomed Eng, 2021, 10.1038/s41551-021-00718-9
J Med Chem, 2020, 31
bioRxiv, 2020, 10.1101/2020.04.13.039917
Tags: HNMT inhibitor | HNMT moduator | HNMT regulation | HNMT inhibition