HNMT

Other Methylation Related Inhibitors

EZH2 PRMT MAT2A LSD1 JMJD G9a/GLP SETD MLL COMT DOT1

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S4589	Amodiaquine dihydrochloride dihydrate	Amodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase with estimated Ki of 18.6 nM. It is also used as an antimalarial and anti-inflammatory agent.	Cell Death Differ, 2023, 10.1038/s41418-023-01167-4 Nat Biomed Eng, 2021, 10.1038/s41551-021-00718-9 J Med Chem, 2020, 31
S3639	Tacrine hydrochloride hydrate	Tacrine (Tetrahydroaminacrine, Tetrahydroaminoacridine) is a centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. It also acts as a histamine N-methyltransferase inhibitor.	Theranostics, January 1, 2024, 593-607 Theranostics, 2024, 593-607

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S4589

Amodiaquine dihydrochloride dihydrate

Amodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase with estimated Ki of 18.6 nM. It is also used as an antimalarial and anti-inflammatory agent.

Cell Death Differ, 2023, 10.1038/s41418-023-01167-4

Nat Biomed Eng, 2021, 10.1038/s41551-021-00718-9

J Med Chem, 2020, 31

S3639

Tacrine hydrochloride hydrate

Tacrine (Tetrahydroaminacrine, Tetrahydroaminoacridine) is a centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. It also acts as a histamine N-methyltransferase inhibitor.

Theranostics, January 1, 2024, 593-607

Theranostics, 2024, 593-607