FTase antagonist | FTase inhibitor | FTase agonist

Not only can you personalize your library with chemicals from within Selleck’s inventory, but we can also purchase chemicals from other companies and integrate them into your custom library. Build the right library for your research endeavors by choosing from compounds in all of our available libraries.

Please contact us at [email protected] to customize your library.

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Specific Compounds Quantities 96 or 384 well Plate Map Dry/solid or DMSO solution

Antibodies

InVivo Antibodies

Therapeutic Antibodies

Bioreagents

qPCR: 2x SYBR Green qPCR Master Mix; 2x SYBR Green qPCR Master Mix(Low ROX); 2x SYBR Green qPCR Master Mix(High ROX)

Protein Assay: Protein A/G Magnetic Beads for IP; Anti-Flag magnetic beads; Anti-Flag Affinity Gel; Anti-Myc magnetic beads; Anti-HA magnetic beads; Magnetic Separator; Poly FLAG Peptide lyophilized powder

Protease Inhibitor Cocktail: Protease Inhibitor Cocktail (EDTA-Free, 100X in DMSO); Phosphatase Inhibitor Cocktail (2 Tubes, 100X)

Cell Biology: Cell Counting Kit-8 (CCK-8)

Animal Experiment: Mouse Direct PCR Kit (For Genotyping)

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Catalog No.	Product Name	Information	Product Use Citations
S0404	Tipifarnib S enantiomer	Tipifarnib S enantiomer ((S)-(-)-R-115777,IND-58359 S enantiomer) is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific inhibitor of farnesyltransferase (FTase) with IC50 of 0.6 nM. Tipifarnib S enantiomer is the less active isomer.
S1453	Tipifarnib (R115777)	Tipifarnib (R115777, IND 58359) is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM, its anti-proliferative effects are most prominent in H-ras or N-ras mutant cells. Phase 3.	Int Immunopharmacol, 2020, 3;83:106462 Cancer Cell, 2019, 36(2):179-193 Cell, 2019, 36(2):179-193
S7465	FTI 277 HCl	FTI 277 HCl is the methyl ester of FTI 277, which is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. FTI 277 HCl inhibits cell growth and induces apoptosis. FTI 277 HCl is effective in clearing HDV viremia.	PLoS Biol, 2021, 19(4):e3001134 Cell Struct Funct, 2021, 46(1):1-9 Nat Commun, 2019, 10(1):273
S7467	LB42708	LB42708 is an orally active farnesyltransferase (FTase) inhibitor with IC50 of 0.8, 1.2, and 2.0 nM toward H-ras, N-ras, and K-ras, respectively.
S0404	Tipifarnib S enantiomer	Tipifarnib S enantiomer ((S)-(-)-R-115777,IND-58359 S enantiomer) is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific inhibitor of farnesyltransferase (FTase) with IC50 of 0.6 nM. Tipifarnib S enantiomer is the less active isomer.
S1453	Tipifarnib (R115777)	Tipifarnib (R115777, IND 58359) is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM, its anti-proliferative effects are most prominent in H-ras or N-ras mutant cells. Phase 3.	Int Immunopharmacol, 2020, 3;83:106462 Cancer Cell, 2019, 36(2):179-193 Cell, 2019, 36(2):179-193
S7465	FTI 277 HCl	FTI 277 HCl is the methyl ester of FTI 277, which is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. FTI 277 HCl inhibits cell growth and induces apoptosis. FTI 277 HCl is effective in clearing HDV viremia.	PLoS Biol, 2021, 19(4):e3001134 Cell Struct Funct, 2021, 46(1):1-9 Nat Commun, 2019, 10(1):273
S7467	LB42708	LB42708 is an orally active farnesyltransferase (FTase) inhibitor with IC50 of 0.8, 1.2, and 2.0 nM toward H-ras, N-ras, and K-ras, respectively.

FTase

FTase Products