FTase

FTase Products

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  • FTase Inhibitors (3)
  • New FTase Products
Catalog No. Product Name Information Product Use Citations Product Validations
S1453 Tipifarnib Tipifarnib is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM, its anti-proliferative effects are most prominent in H-ras or N-ras mutant cells. Phase 3.
Cell Rep, 2023, 42(9):113098
iScience, 2023, 26(5):106695
Res Sq, 2023, rs.3.rs-3154719
S7465 FTI 277 HCl FTI 277 HCl is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. FTI 277 HCl inhibits cell growth and induces apoptosis. FTI 277 HCl is effective in clearing HDV viremia.
Cancer Res, 2023, 83(13):2248-2261
PLoS Biol, 2021, 19(4):e3001134
Cell Struct Funct, 2021, 46(1):1-9
S7467 LB42708 LB42708 is an orally active farnesyltransferase (FTase) inhibitor with IC50 of 0.8, 1.2, and 2.0 nM toward H-ras, N-ras, and K-ras, respectively.
S1453 Tipifarnib Tipifarnib is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM, its anti-proliferative effects are most prominent in H-ras or N-ras mutant cells. Phase 3.
Cell Rep, 2023, 42(9):113098
iScience, 2023, 26(5):106695
Res Sq, 2023, rs.3.rs-3154719
S7465 FTI 277 HCl FTI 277 HCl is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. FTI 277 HCl inhibits cell growth and induces apoptosis. FTI 277 HCl is effective in clearing HDV viremia.
Cancer Res, 2023, 83(13):2248-2261
PLoS Biol, 2021, 19(4):e3001134
Cell Struct Funct, 2021, 46(1):1-9
S7467 LB42708 LB42708 is an orally active farnesyltransferase (FTase) inhibitor with IC50 of 0.8, 1.2, and 2.0 nM toward H-ras, N-ras, and K-ras, respectively.

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Tags: FTase inhibitor|FTase agonist|FTase activator|FTase inducer|FTase antagonist|FTase signaling pathway|FTase assay kit