PTEN

Inhibitory Selectivity

PTEN Products

All (3) PTEN Inhibitors (3)

Catalog No.	Information	Product Use Citations	Product Validations
S7310	SF1670 SF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM.	Cell Mol Immunol, 2020, 10.1038/s41423-020-0363-5 Biochem Pharmacol, 2020, 171:113674 DNA Cell Biol, 2019, 38(5):457-467	A、total of 1.5 μM PTEN inhibitor SF1670 inhibited the expression of PTEN and decreased the level of CD11b
S8651	bpV (HOpic) bpV (HOpic) is a potent inhibitor of PTEN with an IC50 of 14 nM. The IC50s for PTP-β and PTP-1B are about 350- and 1800-fold higher than the IC50 for PTEN, respectively.	J Neurochem, 2015, 133(6):828-43
S8174	VO-Ohpic trihydrate VO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.

Catalog No.

Information

Product Use Citations

Product Validations

S7310

SF1670

SF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM.

Cell Mol Immunol, 2020, 10.1038/s41423-020-0363-5

Biochem Pharmacol, 2020, 171:113674

DNA Cell Biol, 2019, 38(5):457-467

S8651

bpV (HOpic)

bpV (HOpic) is a potent inhibitor of PTEN with an IC50 of 14 nM. The IC50s for PTP-β and PTP-1B are about 350- and 1800-fold higher than the IC50 for PTEN, respectively.

J Neurochem, 2015, 133(6):828-43

S8174

VO-Ohpic trihydrate

VO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.

Catalog No.	Information	Product Use Citations	Product Validations
S7310	SF1670 SF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM.	Cell Mol Immunol, 2020, 10.1038/s41423-020-0363-5 Biochem Pharmacol, 2020, 171:113674 DNA Cell Biol, 2019, 38(5):457-467	A、total of 1.5 μM PTEN inhibitor SF1670 inhibited the expression of PTEN and decreased the level of CD11b
S8651	bpV (HOpic) bpV (HOpic) is a potent inhibitor of PTEN with an IC50 of 14 nM. The IC50s for PTP-β and PTP-1B are about 350- and 1800-fold higher than the IC50 for PTEN, respectively.	J Neurochem, 2015, 133(6):828-43
S8174	VO-Ohpic trihydrate VO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.