PTEN
Inhibitory Selectivity
PTEN Products
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S7310 |
SF1670SF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM. |
A、total of 1.5 μM PTEN inhibitor SF1670 inhibited the expression of PTEN and decreased the level of CD11b
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|
| S8651 |
bpV (HOpic)bpV (HOpic) is a potent inhibitor of PTEN with an IC50 of 14 nM. The IC50s for PTP-β and PTP-1B are about 350- and 1800-fold higher than the IC50 for PTEN, respectively. |
||
| S8174 |
VO-Ohpic trihydrateVO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM. |
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| S9190 |
Oroxin BOroxin B, one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels is found to be downregulated, while PTEN was upregulated after Oroxin B treatment. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S7310 |
SF1670SF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM. |
A、total of 1.5 μM PTEN inhibitor SF1670 inhibited the expression of PTEN and decreased the level of CD11b
|
|
| S8651 |
bpV (HOpic)bpV (HOpic) is a potent inhibitor of PTEN with an IC50 of 14 nM. The IC50s for PTP-β and PTP-1B are about 350- and 1800-fold higher than the IC50 for PTEN, respectively. |
||
| S8174 |
VO-Ohpic trihydrateVO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S9190 |
Oroxin BOroxin B, one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels is found to be downregulated, while PTEN was upregulated after Oroxin B treatment. |
