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PTEN

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Cat.No. Product Name Information Product Use Citations Product Validations
S8651 bpV (HOpic) bpV (HOpic) (Bisperoxovanadium (HOpic)) is a potent inhibitor of PTEN with an IC50 of 14 nM. The IC50s for PTP-β and PTP-1B are about 350- and 1800-fold higher than that for PTEN, respectively.
ACS Nano, October 24 2023, 19652-19666
Science Advances, July 08 2022, eabo0322
Cancer Gene Ther, 2026, 33(3):314-322
S7310 SF1670 SF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM.
J Extracell Biol, 2026, 5(2):e70112
Oncol Rep, 2025, 54(4)125
Nat Biomed Eng, 2024, 10.1038/s41551-024-01273-9
Verified customer review of SF1670
S8174 VO-Ohpic trihydrate VO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.
Antioxidants (Basel), 2026, 15(4)499
Cell Commun Signal, 2025, 23(1):431
Cell Communication and Signaling, 2025, 431
S9190 Oroxin B Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. This compound significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, it potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels are downregulated, while PTEN is upregulated after this chemical treatment.
Antioxidants (Basel), 2026, 15(4)499
Environ Pollut, 2023, 323:121306
Theranostics, 2022, 12(2):910-928
S0918 Ginkgolic acid C17:1 Ginkgolic acid C17:1 (GAC 17:1) inhibits constitutive activation of STAT3 through the abrogation of upstream JAK2 and Src. This compound can induce the substantial expression of PTEN and SHP-1. It induces apoptosis of tumor cells.