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Catalog No. Product Name Information Product Use Citations Product Validations
S7310 SF1670 SF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM.
J Cancer, 2021, 12(7):2140-2150
Front Med (Lausanne), 2021, 8:737859
Elife, 2020, 9e55676
S8174 VO-Ohpic trihydrate VO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.
Front Cell Dev Biol, 2020, 8:594683
Aging (Albany NY), 2020, 24;12(2):1213-1236
Life Sci, 2020, 25;253:117718
S8651 bpV (HOpic) bpV (HOpic) (Bisperoxovanadium (HOpic)) is a potent inhibitor of PTEN with an IC50 of 14 nM. The IC50s for PTP-β and PTP-1B are about 350- and 1800-fold higher than the IC50 for PTEN, respectively.
Int J Mol Sci, 2021, 22(12)6570
Front Cell Dev Biol, 2020, 8:587
J Cell Mol Med, 2020, 24(1):61-78
A5040 PTEN Rabbit Recombinant mAb

PTEN Antibody detects endogenous levels of PTEN.
S0918 Ginkgolic acid C17:1 Ginkgolic acid C17:1 (GAC 17:1) inhibits constitutive activation of STAT3 through the abrogation of upstream JAK2 and Src. Ginkgolic acid C17:1 can induce the substantial expression of PTEN and SHP-1. Ginkgolic acid C17:1 induces apoptosis of tumor cells.
S9190 Oroxin B Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels are downregulated, while PTEN is upregulated after Oroxin B treatment.
J Cancer, 2021, 12(7):2140-2150
S7310 SF1670 SF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM.
J Cancer, 2021, 12(7):2140-2150
Front Med (Lausanne), 2021, 8:737859
Elife, 2020, 9e55676
S8174 VO-Ohpic trihydrate VO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.
Front Cell Dev Biol, 2020, 8:594683
Aging (Albany NY), 2020, 24;12(2):1213-1236
Life Sci, 2020, 25;253:117718
S8651 bpV (HOpic) bpV (HOpic) (Bisperoxovanadium (HOpic)) is a potent inhibitor of PTEN with an IC50 of 14 nM. The IC50s for PTP-β and PTP-1B are about 350- and 1800-fold higher than the IC50 for PTEN, respectively.
Int J Mol Sci, 2021, 22(12)6570
Front Cell Dev Biol, 2020, 8:587
J Cell Mol Med, 2020, 24(1):61-78
A5040 PTEN Rabbit Recombinant mAb

PTEN Antibody detects endogenous levels of PTEN.
S0918 Ginkgolic acid C17:1 Ginkgolic acid C17:1 (GAC 17:1) inhibits constitutive activation of STAT3 through the abrogation of upstream JAK2 and Src. Ginkgolic acid C17:1 can induce the substantial expression of PTEN and SHP-1. Ginkgolic acid C17:1 induces apoptosis of tumor cells.
S9190 Oroxin B Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels are downregulated, while PTEN is upregulated after Oroxin B treatment.
J Cancer, 2021, 12(7):2140-2150