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Bcl-6

Other Apoptosis Related Inhibitors

Caspase Bcl-2 p53 Ferroptosis PD-1/PD-L1 Survivin TNF-alpha MDM2/MDMX KRas IAP
Cat.No. Product Name Information Product Use Citations Product Validations
S8591 FX1 FX1 is a selective BCL6 BTB inhibitor with an IC50 value of 35 μM in reporter assays. This compound shows great selectivity against a panel of 50 different kinases. 10 μM of this chemical fails to significantly inhibit of any of these kinases. It induces apoptosis.
Front Immunol, 2025, 16:1558845
Victoria University of Wellington, 2023,
Haematologica, 2022, 10.3324/haematol.2022.280879
S6937 BI-3802 BI-3802 is a highly potent oncogenic transcription factor BCL6 degrader with strong de-repression of target genes anti-proliferative effects. This compound inhibits the BTB domain of BCL6 with IC50 of ≤3 nM. It exhibits antitumor activity.
Adv Sci (Weinh), 2025, 12(31):e01284
Phytomedicine, 2024, 133:155944
Haematologica, 2022, 10.3324/haematol.2022.280879
S8735 BI-3812 BI-3812 is a highly potent and efficacious BCL6 inhibitor probe compound with an IC50 less than 3 nM.
Haematologica, 2022, 10.3324/haematol.2022.280879
bioRxiv, 2022, 10.1101/2022.11.03.514941
S8250 79-6 (CID5721353) 79-6 (CID5721353), a BCL6 inhibitor, has a Kd value of 138 μM.
Cell Rep Med, 2022, 3(9):100744