Home Apoptosis -ER stress & UPR -MAPK ASK

ASK

Isoform-selective Products

ASK Products

  • All (5)
  • ASK Inhibitors (4)
  • New ASK Products
Catalog No. Product Name Information Product Use Citations Product Validations
S8292 Selonsertib (GS-4997) Selonsertib (GS-4997) is a highly selective and potent once-daily oral ASK1 inhibitor with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.
Cell Metab, 2024, 36(11):2468-2488.e7
Cell Death Dis, 2024, 15(9):662
iScience, 2024, 27(8):110598
S8289 NQDI-1 NQDI 1, an inhibitor of ASK1(apoptosis signal-regulating kinase 1), attenuates acute ischemic renal injury by modulating oxidative stress and cell death.
Redox Biol, 2023, 60:102618
J Neuroinflammation, 2023, 20(1):22
J Neuroinflammation, 2023, 20(1):22
F1172 ASK1 Rabbit mAb ASK 1,ASK1
S0067 GS-444217 GS-444217 (ASK1-IN-1) is a potent, selective, orally available and ATP-competitive inhibitor of ASK1 (apoptosis signal-regulating kinase 1) with IC50 of 2.87 nM.
E2379 ASK1-IN-2 ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM.
S8292 Selonsertib (GS-4997) Selonsertib (GS-4997) is a highly selective and potent once-daily oral ASK1 inhibitor with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.
Cell Metab, 2024, 36(11):2468-2488.e7
Cell Death Dis, 2024, 15(9):662
iScience, 2024, 27(8):110598
S8289 NQDI-1 NQDI 1, an inhibitor of ASK1(apoptosis signal-regulating kinase 1), attenuates acute ischemic renal injury by modulating oxidative stress and cell death.
Redox Biol, 2023, 60:102618
J Neuroinflammation, 2023, 20(1):22
J Neuroinflammation, 2023, 20(1):22
S0067 GS-444217 GS-444217 (ASK1-IN-1) is a potent, selective, orally available and ATP-competitive inhibitor of ASK1 (apoptosis signal-regulating kinase 1) with IC50 of 2.87 nM.
E2379 ASK1-IN-2 ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM.

Choose Selective ASK Inhibitors

Tags: ASK inhibition | ASK cancer | ASK activation | ASK target | ASK tumor | ASK phosphorylation | ASK activity | ASK inhibitor drugs | ASK kinase assay | ASK inhibitor cancer | ASK inhibitor therapy | ASK signaling pathway | ASK inhibitor review