• Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S8289 NQDI-1 <1 mg/mL 21 mg/mL <1 mg/mL
S8292 Selonsertib (GS-4997) <1 mg/mL 36 mg/mL 24 mg/mL
Catalog No. Information Product Use Citations Product Validations


NQDI 1, an inhibitor of ASK1(apoptosis signal-regulating kinase 1), attenuates acute ischemic renal injury by modulating oxidative stress and cell death.


Selonsertib (GS-4997)

GS-4997 is a highly selective and potent once-daily oral ASK1 inhibitor with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.

Tags: ASK inhibition | ASK cancer | ASK activation | ASK target | ASK tumor | ASK phosphorylation | ASK activity | ASK inhibitor drugs | ASK kinase assay | ASK inhibitor cancer | ASK inhibitor therapy | ASK signaling pathway | ASK inhibitor review