5-alpha Reductase

Signaling Pathway Map

Research Area

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S1202 Dutasteride <1 mg/mL 62 mg/mL 6 mg/mL
S1197 Finasteride <1 mg/mL 75 mg/mL 75 mg/mL
S4593 Chlormadinone acetate <1 mg/mL 27 mg/mL 1 mg/mL
Catalog No. Information Product Use Citations Product Validations


Dutasteride is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT).



Finasteride is a potent, reversible inhibitor of the rat type 1 5 alpha-reductase with Ki of 10.2 nM, used in the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB).


Chlormadinone acetate

Chlormadinone acetate is a steroidal progestin with additional antiandrogen and antigonadotropic effects, used often in combinations as an oral contraceptive. Its half-life is about 34-38 hours.

Tags: 5-alpha reductase inhibition | 5-alpha reductase deficiency | 5-alpha reductase enzyme | 5-alpha reductase syndrome | 5-alpha reductase activity | 5-alpha reductase treatment | 5-alpha reductase drugs | 5-alpha reductase assay | 5-alpha reductase pseudohermaphrodites | 5-alpha reductase inhibitor drugs | 5-alpha reductase inhibitor prostate cancer | 5-alpha reductase pathway | 5-alpha reductase inhibitor review