5-alpha Reductase

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5-alpha Reductase Signaling Pathways

5-alpha Reductase Products

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Catalog No. Product Name Information Product Use Citations Product Validations
S1197 Finasteride Finasteride (MK-906) is a potent, reversible inhibitor of the rat type 1 5 alpha-reductase with Ki of 10.2 nM, used in the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB).
Cell Stem Cell, 2020, 27(6):876-889.e12
Steroids, 2019, 150:108434
Cell Death Dis, 2018,
S1202 Dutasteride Dutasteride (GI198745, GG-745) is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT).
Cancer Rep (Hoboken), 2021, e1418
Drug Test Anal, 2020, 10.1002/dta.2917
Cell Stem Cell, 2020, 27(6):876-889.e12
S4593 Chlormadinone acetate Chlormadinone acetate (Gestafortin) is a steroidal progestin with additional antiandrogen and antigonadotropic effects, used often in combinations as an oral contraceptive. Its half-life is about 34-38 hours.
S2283 Cinchonine(LA40221) Cinchonine (LA40221) is an alkaloid and a stereoisomer and pseudo-enantiomer of cinchonidine.
S1197 Finasteride Finasteride (MK-906) is a potent, reversible inhibitor of the rat type 1 5 alpha-reductase with Ki of 10.2 nM, used in the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB).
Cell Stem Cell, 2020, 27(6):876-889.e12
Steroids, 2019, 150:108434
Cell Death Dis, 2018,
S1202 Dutasteride Dutasteride (GI198745, GG-745) is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT).
Cancer Rep (Hoboken), 2021, e1418
Drug Test Anal, 2020, 10.1002/dta.2917
Cell Stem Cell, 2020, 27(6):876-889.e12
S4593 Chlormadinone acetate Chlormadinone acetate (Gestafortin) is a steroidal progestin with additional antiandrogen and antigonadotropic effects, used often in combinations as an oral contraceptive. Its half-life is about 34-38 hours.
Tags: 5-alpha reductase inhibition | 5-alpha reductase deficiency | 5-alpha reductase enzyme | 5-alpha reductase syndrome | 5-alpha reductase activity | 5-alpha reductase treatment | 5-alpha reductase drugs | 5-alpha reductase assay | 5-alpha reductase pseudohermaphrodites | 5-alpha reductase inhibitor drugs | 5-alpha reductase inhibitor prostate cancer | 5-alpha reductase pathway | 5-alpha reductase inhibitor review