Lasmiditan

For research use only.

Catalog No.S5064 Synonyms: Reyvow

Lasmiditan Chemical Structure

CAS No. 439239-90-4

Lasmiditan (Reyvow) is a highly selective 5-hydroxytryptamine (serotonin) receptor 1F (5-HT1F) agonist that can be used as a promising acute anti-migraine therapy.

Purity & Quality Control

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Biological Activity

Description Lasmiditan (Reyvow) is a highly selective 5-hydroxytryptamine (serotonin) receptor 1F (5-HT1F) agonist that can be used as a promising acute anti-migraine therapy.
Targets
5-HT1F [1]
()

Protocol

Solubility (25°C)

In vitro DMSO 75 mg/mL (198.74 mM)
Water Insoluble
Ethanol ''75 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 377.36
Formula

C19H18F3N3O2

CAS No. 439239-90-4
Storage powder
in solvent
Synonyms Reyvow

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
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Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

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  • Computed Result

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Molecular Weight Calculator

Molecular Weight Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04881747 Completed Drug: Lasmiditan Healthy Eli Lilly and Company May 14 2021 Phase 1
NCT04081324 Completed Drug: Lasmiditan|Drug: Placebo Healthy Eli Lilly and Company November 13 2019 Phase 1
NCT03988088 Completed Drug: Lasmiditan Migraine Eli Lilly and Company July 22 2019 Phase 1
NCT03962738 Completed Drug: Lasmiditan|Drug: Placebo Migraine Eli Lilly and Company May 31 2019 Phase 2
NCT03579940 Completed Drug: Lasmiditan|Drug: Placebo Healthy Eli Lilly and Company June 27 2018 Phase 1
NCT03459612 Completed Drug: Lasmiditan|Drug: Placebo|Drug: Diphenhydramine Healthy Eli Lilly and Company March 26 2018 Phase 1

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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5-HT Receptor Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID