Cefsulodin sodium

Catalog No.S3670 Synonyms: Sulcephalosporin

Cefsulodin sodium Chemical Structure

Molecular Weight(MW): 554.53

Cefsulodin is a β-lactam antibiotic and inhibits mPTPB with the IC50 of 16 μM.

Size Price Stock Quantity  
USD 147 In stock
Bulk Discount

Free Overnight Delivery on orders over $ 500
Next day delivery by 10:00 a.m. Order now.

Purity & Quality Control

Choose Selective phosphatase Inhibitors

Biological Activity

Description Cefsulodin is a β-lactam antibiotic and inhibits mPTPB with the IC50 of 16 μM.
Targets
mPTPB [1]
(Cell-free)
16 μM
In vitro

Cefsulodin is a third generation β-lactam cephalosporin antibiotic, as a novel pTyr pharmacophore for mPTPB. Cefsulodin has also been found to exhibit inhibitory activity against SHP2 and PTP1B[1].

In vivo Cefsulodin shows maximum plasma and tissue levels 15-30 minutes after administration of a single dose of 20 mg/kg. In mice, the renal level of cefsulodin is slightly lower than the plasma level, and in rats and dogs, the renal level of cefsulodin is higher than the plasma level. The concentration of cefsulodin in the lung is relatively high in rats and dogs. On the other hand, the hepatic level is very low in all test animal species. The main route of excretion of cefsulodin is the urinary tract. About 80% of cefsulodin is excreted into the urine[3].

Protocol

Animal Research:[2]
- Collapse
  • Animal Models: SLC-ddY mice, JCL-Sprague Dawly rats, mongrel dogs
  • Formulation: PBS
  • Dosages: 20 mg/kg
  • Administration: s.c.
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 100 mg/mL (180.33 mM)
Water 100 mg/mL (180.33 mM)
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 554.53
Formula

C22H19N4O8S2.Na

CAS No. 52152-93-9
Storage powder
in solvent
Synonyms Sulcephalosporin

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field
Tags: buy Cefsulodin sodium | Cefsulodin sodium supplier | purchase Cefsulodin sodium | Cefsulodin sodium cost | Cefsulodin sodium manufacturer | order Cefsulodin sodium | Cefsulodin sodium distributor
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID