Alcohol Dehydrogenase Rabbit mAb

Catalog No.: F3971

    Application: Reactivity:

    Usage Information

    Dilution
    1:1000 - 1:10000
    1:250 - 1:500
    1:500 - 1:1000
    Application
    WB, IHC, IF
    Reactivity
    Human, Mouse, Rat
    Source
    Rabbit
    Storage Buffer
    PBS, pH 7.2+50% Glycerol+0.05% BSA+0.01% NaN3
    Storage (from the date of receipt)
    -20°C (avoid freeze-thaw cycles), 2 years
    Predicted MW
    40 kDa

    Datasheet & SDS

    Biological Description

    Specificity
    Alcohol Dehydrogenase Rabbit mAb detects endogenous levels of total alcohol dehydrogenase protein.
    Clone
    C8G21
    Synonym(s)
    ADH1, ADH1A, Alcohol dehydrogenase 1A, Alcohol dehydrogenase subunit alpha
    Background
    Alcohol dehydrogenase (ADH), is the constitutive enzyme which are a family of NAD(P)H-dependent oxidoreductases that catalyze the reversible conversion of alcohols to aldehydes or ketones, and vice versa. Structurally, ADHs typically exist as dimers or tetramers with a conserved zinc-binding catalytic domain and a Rossmann-fold domain for nucleotide (NAD⁺/NADP⁺) binding. They are widely expressed in microorganisms, plants, and animals, with multiple isoenzymes in humans showing tissue-specific expression, particularly in the liver where they play a central role in ethanol metabolism. Functionally, ADHs are essential for detoxification, energy metabolism, and biosynthesis of various compounds, and they are extensively exploited in biotechnology for the stereoselective synthesis of chiral alcohols.
    References
    • https://pubmed.ncbi.nlm.nih.gov/32060695/

    Tech Support

    Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

    Handling Instructions

    Tel: +1-832-582-8158 Ext:3
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