Pyridostigmine Bromide

For research use only.

Catalog No.S1608

1 publication

Pyridostigmine Bromide  Chemical Structure

CAS No. 101-26-8

Pyridostigmine Bromide is a parasympathomimetic and a reversible cholinesterase inhibitor.

Selleck's Pyridostigmine Bromide has been cited by 1 publication

1 Customer Review

  • Acetylcholine (ACh)-related protein expression in vivo. Choline acetyltransferase (ChAT) in the ischemic area were determined among 3 experimental groups. Data of Western blotting are represented as fold of control.

    J Am Heart Assoc 2014 3(3), e000804. Pyridostigmine Bromide purchased from Selleck.

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Biological Activity

Description Pyridostigmine Bromide is a parasympathomimetic and a reversible cholinesterase inhibitor.
AChR [1]



Solubility (25°C)

In vitro DMSO 52 mg/mL (199.14 mM)
Water 52 mg/mL (199.14 mM)
Ethanol 52 mg/mL (199.14 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 261.12


CAS No. 101-26-8
Storage powder
in solvent
Synonyms N/A
Smiles C[N+]1=CC=CC(=C1)OC(=O)N(C)C.[Br-]

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Dilution Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04226170 Recruiting Drug: DAS-001 Myasthenia Gravis DAS-MG Inc April 8 2021 Phase 2
NCT02357225 Terminated Drug: Pyridostigmine Bromide Pompe Disease University of Florida August 2015 Early Phase 1
NCT02157545 Withdrawn -- Muscle Relaxants Shashi Bhatt MD|University of Toledo Health Science Campus March 2014 --
NCT01993680 Completed Drug: Pyridostigmine bromide|Drug: fludrocortisone Autonomic Disturbances in Parkinson''s Disease Christian Baumann|University of Zurich June 2012 Phase 2
NCT01370512 Completed Drug: Droxidopa|Drug: Pyridostigmine Bromide Orthostatic Hypotension Mayo Clinic|National Institute of Neurological Disorders and Stroke (NINDS) November 2011 Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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AChR Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID