New Dehydrogenase Inhibitors

Catalog No. Product Name Information
E6773 Olorofim(F901318) Olorofim (F901318) is a reversible inhibitor of dihydroorotate dehydrogenase (DHODH), an oxidoreductase that catalyzes the fourth step in the de novo synthesis of pyrimidines. It exhibits potential for the treatment of invasive mold infections and thermally dimorphic fungi that are refractory to or resistant to clinically available antifungals.
E6693 PKUMDL-WQ-2101 PKUMDL‑WQ‑2101 is a non‑NAD⁺‑competing allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 34.8 μM. It exhibits antitumor activity, selectively inhibits de novo serine synthesis in cancer cells, and reduces tumor growth in vivo.
F0233 LDHA Antibody [M1G9] Lactate Dehydrogenase A/LDHA,LDHA,LDH-A
All Dehydrogenase Inhibitors