| E6773 |
Olorofim(F901318) |
Olorofim (F901318) is a reversible inhibitor of dihydroorotate dehydrogenase (DHODH), an oxidoreductase that catalyzes the fourth step in the de novo synthesis of pyrimidines. It exhibits potential for the treatment of invasive mold infections and thermally dimorphic fungi that are refractory to or resistant to clinically available antifungals. |
| E6693 |
PKUMDL-WQ-2101 |
PKUMDL‑WQ‑2101 is a non‑NAD⁺‑competing allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 34.8 μM. It exhibits antitumor activity, selectively inhibits de novo serine synthesis in cancer cells, and reduces tumor growth in vivo. |
| F0233 |
LDHA Antibody [M1G9] |
Lactate Dehydrogenase A/LDHA,LDHA,LDH-A |