New Dehydrogenase Inhibitors
| Cat.No. | Product Name | Information |
|---|---|---|
| S8530 | BAY 1436032 | BAY-1436032 is a highly selective, potent and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1). It is a double-digit nanomolar and selective pan-inhibitor of the enzymatic activity of various IDH1-R132X mutants in vitro and displays potent inhibition of 2-HG release (nanomolar range) in patient derived and engineered cell lines expressing different IDH1 mutants. |
| S5800 | Alda 1 | Alda 1 is an ALDH2 agonist that activates catalysis for both wild-type ALDH2 (ALDH2*1) and ALDH2*2. |
| ≡ All Dehydrogenase Inhibitors | ||
