New JNK Inhibitors

HomeNew JNK Inhibitors
Catalog No. Product Name Information
E1955 TNG348 TNG348 is an orally bioavailable allosteric inhibitor targeting the ubiquitin-specific protease USP1. It selectively and potently blocks USP1 activity, preventing deubiquitination of proliferative PCNA and FANCD2, which disrupts DNA repair mechanisms. TNG348 demonstrates inhibitory effects against BRCA1/2-mutated and homologous recombination-deficient (HRD) breast and ovarian cancers .
F0196 JNK2 Antibody [J8J7]
E8271 Sanguinarine citrate Sanguinarine (gluconate) is a benzophenanthridine alkaloid derived from the root of Sanguinaria canadensis. It activates reactive oxygen species (ROS), c-Jun N-terminal kinase (JNK), and nuclear factor-kappaB (NF-κB) signaling pathways to induce apoptosis in head and neck tumor cells and animal models. It also exhibits potent anti-bacterial and anti-inflammatory activities.
F1069 Phospho-c-Jun (Ser63) Antibody [A1M19] c-Jun (phospho S63),c-Jun (phospho S73),p-c-Jun,Phospho-c-Jun (Ser63),Phospho-c-Jun (Ser63) II,Phospho-c-Jun (Ser73)
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