GPR Modulators

Catalog No.	Product Name	Information
E1928	Azelaprag	Azelaprag (AMG 986) is a potent agonist of apelin receptor (APJ) with an EC50 of 0.32 nM. It exhibits potential and can be used in Heart failure (HF) research.
E4773	NOX-6-18（GPR132-B-160）	NOX-6-18 (GPR132-B-160) is a potent and selective antagonist of GPR132 with an IC50 of 17 nM. It regulates macrophage reprogramming within pancreatic islets, reduces weight gain, and improves glucose metabolism in mice on a high-fat diet.
E4875	Lodoxamide	Lodoxamide (U-42585E free acid) is a potent agonist of GPR35 with an EC50 of 1 nM. It also inhibits eosinophil peroxidase release after IgA activation and reduces eosinophil cationic protein and eosinophil-derived neurotoxin, suggesting direct effects on eosinophils. It is a mast cell stabilizer used to treat asthma, allergic conjunctivitis, and superior limbic keratoconjunctivitis.
F2247	LGR5 Antibody [K18M7]
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