Mitochondrial pyruvate carrier

Other Metabolism Related Inhibitors

Dehydrogenase Transferase DPP Aminopeptidase Procollagen C Proteinase P450 (e.g. CYP17) Phospholipase (e.g. PLA) Factor Xa PDE DHFR

Cat.No.	Product Name	Information	Product Use Citations
S5317	UK-5099 (PF-1005023)	UK5099 (PF-1005023) is a potent inhibitor of the mitochondrial pyruvate carrier, inhibiting pyruvate transport across the plasma membrane of trypanosomes with Ki value of 49 μM.	Cell Stem Cell, 2025, 32(5):759-777.e13 bioRxiv, 2025, 2025.02.07.637120 J Transl Med, 2024, 22(1):283
S7454	Azemiglitazone (MSDC-0602)	Azemiglitazone (MSDC-0602) is a direct mitochondrial pyruvate carrier (MPC) inhibitor that modulates central carbon metabolism in mice and humans.
S9951	MSDC-0602K Potassium	MSDC-0602K is a insulin sensitizer that modulates the mitochondrial pyruvate carrier (MPC).

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S5317

UK-5099 (PF-1005023)

UK5099 (PF-1005023) is a potent inhibitor of the mitochondrial pyruvate carrier, inhibiting pyruvate transport across the plasma membrane of trypanosomes with Ki value of 49 μM.

Cell Stem Cell, 2025, 32(5):759-777.e13

bioRxiv, 2025, 2025.02.07.637120

J Transl Med, 2024, 22(1):283

S7454

Azemiglitazone (MSDC-0602)

Azemiglitazone (MSDC-0602) is a direct mitochondrial pyruvate carrier (MPC) inhibitor that modulates central carbon metabolism in mice and humans.

S9951

MSDC-0602K Potassium

MSDC-0602K is a insulin sensitizer that modulates the mitochondrial pyruvate carrier (MPC).