Glucosylceramide Synthase

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Glucosylceramide Synthase Products

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  • Glucosylceramide Synthase Inhibitors (3)
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Catalog No. Product Name Information Product Use Citations Product Validations
E0646New Ibiglustat succinate Ibiglustat succinate (Venglustat succinate) is a glucosylceramide (GlcCer) synthase inhibitor that blocks the formation of glucosylceramide.
S4433 Eliglustat hemitartrate Eliglustat hemitartrate (Genz-112638, Eliglustat tartrate) is a potent, specific and orally active inhibitor of glucosylceramide synthase with IC50 of 24 nM.
Biochim Biophys Acta Mol Cell Biol Lipids, 2021, 1866(1):158817
Biol Pharm Bull, 2021, 44(10):1419-1426
S7852 Eliglustat Eliglustat (GENZ-112638) inhibits glucosylceramide synthase(GCS) (IC50=20 nM in intact MDCK cells), thus reducing the load of glucosylceramide influx into the lysosome.
Biochim Biophys Acta Mol Cell Biol Lipids, 2021, 1866(1):158817
Biol Pharm Bull, 2021, 44(10):1419-1426
J Clin Immunol, 2020, 1-10
E0646New Ibiglustat succinate Ibiglustat succinate (Venglustat succinate) is a glucosylceramide (GlcCer) synthase inhibitor that blocks the formation of glucosylceramide.
S4433 Eliglustat hemitartrate Eliglustat hemitartrate (Genz-112638, Eliglustat tartrate) is a potent, specific and orally active inhibitor of glucosylceramide synthase with IC50 of 24 nM.
Biochim Biophys Acta Mol Cell Biol Lipids, 2021, 1866(1):158817
Biol Pharm Bull, 2021, 44(10):1419-1426
S7852 Eliglustat Eliglustat (GENZ-112638) inhibits glucosylceramide synthase(GCS) (IC50=20 nM in intact MDCK cells), thus reducing the load of glucosylceramide influx into the lysosome.
Biochim Biophys Acta Mol Cell Biol Lipids, 2021, 1866(1):158817
Biol Pharm Bull, 2021, 44(10):1419-1426
J Clin Immunol, 2020, 1-10
E0646New Ibiglustat succinate Ibiglustat succinate (Venglustat succinate) is a glucosylceramide (GlcCer) synthase inhibitor that blocks the formation of glucosylceramide.
Tags: Glucosylceramide Synthase inhibitor|Glucosylceramide Synthase agonist|Glucosylceramide Synthase activator|Glucosylceramide Synthase inducer|Glucosylceramide Synthase antagonist|Glucosylceramide Synthase signaling pathway|Glucosylceramide Synthase assay kit