HomeNew Histone Methyltransferase Inhibitors

New Histone Methyltransferase Inhibitors

Catalog No. Product Name Information
E1728 STC-15 STC-15 is an oral, small-molecule inhibitor of RNA methyltransferase METTL3. It inhibits tumor growth through the activation of anti-cancer immune responses associated with increased interferon signaling and synergizes with T-cell checkpoint blockade.
E1163 MS177 MS177 is an EZH2-targeting PRTOAC degrader and a potent inhibitor of enzymatic EZH2, that effectively depletes both canonical EZH2–PRC2 and noncanonical EZH2–cMyc complexes. MS177 induces leukemia cell growth inhibition, apoptosis, and cell cycle progression arrest.
E2911 UZH2 UZH2 is a potent and selective METTL3 inhibitor with an IC50 value of 5 nM in TR-FRET assay.
≡ All Histone Methyltransferase Inhibitors