Adrenergic Receptor

Adrenergic Receptor Inhibitors | Agonists | Antagonists (65)


Cat.No. Product Name Information Product Use Citation Customer Product Validation
S2507 Salbutamol Sulfate Salbutamol Sulfate is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 µM.
S1324 Doxazosin Mesylate Doxazosin, a quinazoline-derivative, selectively antagonizes postsynaptic α1-adrenergic receptors, used in the treatment of high blood pressure and urinary retention associated with benign prostatic hyperplasia.
  • J Clin Invest, 2013, 123(12):5119-34
  • Antiviral Res, 2015, 120:140-6
S2516 Xylazine HCl Xylazine is an α2-Adrenergic receptor agonist, used as a sedative and muscle relaxant.
  • Acad Radiol, 2012, 19(3):358-65
S4009 Mirabegron Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.
S1409 Alfuzosin HCl Alfuzosin HCl is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH).
  • Prostate, 2016, 76(8):757-66
S1283 Asenapine maleate Asenapine maleate is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with bipolar disorder.
S3083 Indacaterol Maleate Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36.
S2566 Isoprenaline HCl Isoprenaline is a non-selective beta-adrenergic receptor agonist, used for the treatment of bradycardia and heart block.
S2020 Formoterol Hemifumarate Formoterol Hemifumarate is a potent, selective and long-acting β2-adrenoceptor agonist used in the management of asthma and chronic obstructive pulmonary disease(COPD).
S1613 Silodosin Silodosin is a highly selective α1A-adrenoceptor antagonist, used in treatment of benign prostatic hyperplasia.
Cat.No. Product Name Information Product Use Citation Customer Product Validation
S1549 Nebivolol Nebivolol selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM.
S2521 Epinephrine bitartrate Epinephrine bitartrate is an alpha- and beta-adrenergic receptor stimulator.
S2691 BMY 7378 BMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pKi of 8.3.
S2458 Clonidine HCl Clonidine HCl is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg.
S2495 Oxymetazoline HCl Oxymetazoline HCl is an α1 and α2 adrenergic receptor agonist, used to relieve nasal discomfort caused by colds, allergies, and hay fever.
S1424 Prazosin HCl Prazosin HCl is a competitive alpha-1 adrenoceptor antagonist, used to treat high blood pressure or benign prostatic hyperplasia.
S2038 Phentolamine Mesylate Phentolamine Mesylate is a reversible and nonselective alpha-adrenergic receptor antagonist, used for the prevention or control of hypertensive episodes.
S4076 Propranolol HCl Propranolol HCl is a competitive non-selective beta-adrenergic receptors inhibitor with IC50 of 12 nM.
S1206 Bisoprolol fumarate Bisoprolol fumarate is a selective type β1 adrenergic receptor blocker.
S2522 L-Adrenaline L-Adrenaline belongs to a group of the compounds known as catecholamines.
Cat.No. Product Name Information Product Use Citation Customer Product Validation
S3041 Droxidopa Droxidopa is a psychoactive drug and acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline).
S3075 Dexmedetomidine Dexmedetomidine is a sedative medication used by intensive care units and anesthetists.
S2126 Naftopidil Naftopidil is a selective α1-adrenergic receptor antagonist with Ki of 3.7 nM, 20 nM, and 1.2 nM for α1a, α1b, and α1d, respectively, used for the treatment of benign prostatic hyperplasia.
S2517 Maprotiline HCl Maprotiline HCl is a selective noradrenalin re-uptake inhibitor, used in the treatment of depression.
S1831 Carvedilol Carvedilol is a non-selective beta blocker/alpha-1 blocker, used to treat congestive heart failure (CHF) and high blood pressure.
  • Res Pharm Sci, 2015, 10(5):388-96
S2569 Phenylephrine HCl Phenylephrine HCl is a selective α1-adrenergic receptor agonist, used primarily as a decongestant.
S2059 Terazosin HCl Terazosin HCl is a selective α1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH).
S1856 Metoprolol Tartrate Metoprolol Tartrate is a selective β1 receptor blocker medication, used to treat hypertension and heart failure.
S1387 Naftopidil DiHCl Naftopidil DiHCl is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.
S2509 Sotalol Sotalol is a non-selective beta blocker and a potassium channel blocker with an IC50 of 43 μM.
  • Toxicol Appl Pharmacol, 2015, 285(1):51-60
Cat.No. Product Name Information Product Use Citation Customer Product Validation
S2519 Naphazoline HCl Naphazoline HCl is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.
S2533 Ritodrine HCl Ritodrine HCl is a hydrochloride salt of ritodrine which is a β-2 adrenergic receptor agonist.
S4123 Timolol Maleate Timolol Maleate is a non-selective, beta-adrenergic receptor antagonist for β1/β2 with Ki of 1.97 nM/2.0 nM.
S2438 Synephrine HCl SynephrineHCl (Oxedrine, p-Synephrine) is a sympathomimetic α-adrenergic receptor (AR) agonist.
S2090 Dexmedetomidine HCl Dexmedetomidine HCl is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.
S2499 Phenoxybenzamine HCl Phenoxybenzamine HCl is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM.
S4065 Guanabenz Acetate Guanabenz Acetate is an selective agonist of α2a-adrenergic receptor, α2b-adrenergic receptor and α2c-adrenergic receptor with pEC50 of 8.25, 7.01 and ~5, respectively.
S1827 Betaxolol HCl Betaxolol is a β1 adrenergic receptor blocker with IC50 of 6 μM.
S2092 Detomidine HCl Detomidine HCl produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.
S4010 Acebutolol HCl Acebutolol is a β-adrenergic receptors antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias.
Cat.No. Product Name Information Product Use Citation Customer Product Validation
S1437 Tizanidine HCl Tizanidine HCl is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.
S3061 Epinephrine HCl Epinephrine HCl is a hormone and a neurotransmitter.
S3060 Medetomidine HCl Medetomidine is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.
S2523 DL-Adrenaline DL-Adrenaline is a hormone and a neurotransmitter secreted by the medulla of the adrenal glands.
S2615 Noradrenaline bitartrate monohydrate Noradrenaline bitartrate monohydrate is a direct alpha-adrenergic receptors stimulator.
S4127 Terbutaline Sulfate Terbutaline Sulfate is a selective β2-adrenergic receptor agonist with IC50 of 53 nM.
S2576 Xylometazoline HCl Xylometazoline is an α-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at α2B-adrenoceptor subtype with EC50 of 99 μM.
S4135 Clorprenaline HCl Clorprenaline HCl is a β2-receptor agonist, it has a significant expansion of the bronchial effect.
S2373 Yohimbine HCl Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
S2362 Synephrine Synephrine, a natural protoalkaloid in the extract of bitter orange and other citrus species, is commonly used for weight loss.
Cat.No. Product Name Information Product Use Citation Customer Product Validation
S4266 Brimonidine Tartrate Brimonidine Tartrate is a highly selective α-adrenergic receptor agonist with EC50 of 0.45 nM for the α2A adrenoreceptor, and used to treat open-angle glaucoma or ocular hypertension.
S1642 Methyldopa Methyldopa (Aldomet) is a DOPA decarboxylase competitive inhibitor with an ED50 of 21.8 mg/kg.
S2086 Ivabradine HCl Ivabradine HCl, a new If inhibitor with IC 50 of 2.9 μM which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent.
S2113 Cisatracurium Besylate Cisatracurium Besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.
S3185 Adrenalone HCl Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic, mainly acts on alpha-1 adrenergic receptors.
S2091 Betaxolol Betaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.
S4043 Tetrahydrozoline HCl Tetrahydrozoline HCl is an imidazoline derivative with alpha receptor agonist activity.
S4100 Esmolol HCl Esmolol is a cardioselective b-blocker, used to control rapid heartbeats or abnormal heart rhythms.
S4124 Tolazoline HCl Tolazoline is a non-selective competitive α-adrenergic receptor antagonist.
S2545 Scopine Scopine is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock.
Cat.No. Product Name Information Product Use Citation Customer Product Validation
S4278 Carteolol HCl Carteolol HCl is a β-adrenoceptor antagonist, used for the treatment of glaucoma.
S4277 Bambuterol HCl Bambuterol HCl is a potent β-adrenoceptor agonist, used in the treatment of asthma.
S4291 Labetalol HCl Labetalol HCl is a dual antagonist for both selective alpha1-adrenergic and nonselective beta-adrenergic receptors, used in the treatment of high blood pressure.
S4296 Salmeterol Xinafoate Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms.
S4085 Levobetaxolol HCl Levobetaxolol exhibits a higher affinity at cloned human β1 and β2 receptors with Ki value of 0.76 nM and 32.6 nM, respectively.
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All Adrenergic Receptor Products

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Cat.No. Product Name Solubility (25°C)
Water DMSO Ethanol
S2507 Salbutamol Sulfate 68 mg/mL <1 mg/mL <1 mg/mL
S1324 Doxazosin Mesylate <1 mg/mL 15 mg/mL <1 mg/mL
S2516 Xylazine HCl 12 mg/mL 50 mg/mL 50 mg/mL
S4009 Mirabegron <1 mg/mL 79 mg/mL 8 mg/mL
S1409 Alfuzosin HCl 85 mg/mL 85 mg/mL 85 mg/mL
S1283 Asenapine maleate <1 mg/mL 80 mg/mL <1 mg/mL
S3083 Indacaterol Maleate <1 mg/mL 102 mg/mL <1 mg/mL
S2566 Isoprenaline HCl 50 mg/mL 50 mg/mL <1 mg/mL
S2020 Formoterol Hemifumarate <1 mg/mL 80 mg/mL <1 mg/mL
S1613 Silodosin <1 mg/mL 99 mg/mL 99 mg/mL
S1549 Nebivolol <1 mg/mL 88 mg/mL <1 mg/mL
S2521 Epinephrine bitartrate 67 mg/mL 67 mg/mL <1 mg/mL
S2691 BMY 7378 92 mg/mL 92 mg/mL 20 mg/mL
S2458 Clonidine HCl 53 mg/mL 53 mg/mL 53 mg/mL
S2495 Oxymetazoline HCl 59 mg/mL 59 mg/mL 59 mg/mL
S1424 Prazosin HCl <1 mg/mL 4 mg/mL <1 mg/mL
S2038 Phentolamine Mesylate 76 mg/mL 76 mg/mL 76 mg/mL
S4076 Propranolol HCl 6 mg/mL 59 mg/mL <1 mg/mL
S1206 Bisoprolol fumarate 88 mg/mL 88 mg/mL 88 mg/mL
S2522 L-Adrenaline <1 mg/mL 4 mg/mL <1 mg/mL
S3041 Droxidopa <1 mg/mL <1 mg/mL <1 mg/mL
S3075 Dexmedetomidine 40 mg/mL 40 mg/mL 40 mg/mL
S2126 Naftopidil <1 mg/mL 79 mg/mL <1 mg/mL
S2517 Maprotiline HCl <1 mg/mL 63 mg/mL 24 mg/mL
S1831 Carvedilol <1 mg/mL 81 mg/mL 4 mg/mL
S2569 Phenylephrine HCl 41 mg/mL 41 mg/mL 41 mg/mL
S2059 Terazosin HCl <1 mg/mL 26 mg/mL <1 mg/mL
S1856 Metoprolol Tartrate 100 mg/mL 100 mg/mL 31 mg/mL
S1387 Naftopidil DiHCl <1 mg/mL 41 mg/mL 2 mg/mL
S2509 Sotalol 62 mg/mL 62 mg/mL <1 mg/mL
S2519 Naphazoline HCl 49 mg/mL 17 mg/mL 22 mg/mL
S2533 Ritodrine HCl 65 mg/mL 65 mg/mL 65 mg/mL
S4123 Timolol Maleate <1 mg/mL 86 mg/mL 86 mg/mL
S2438 Synephrine HCl 41 mg/mL 14 mg/mL 4 mg/mL
S2090 Dexmedetomidine HCl <1 mg/mL 48 mg/mL 48 mg/mL
S2499 Phenoxybenzamine HCl 17 mg/mL 68 mg/mL 68 mg/mL
S4065 Guanabenz Acetate <1 mg/mL 58 mg/mL 5 mg/mL
S1827 Betaxolol HCl 69 mg/mL 69 mg/mL 69 mg/mL
S2092 Detomidine HCl 45 mg/mL 45 mg/mL 45 mg/mL
S4010 Acebutolol HCl 75 mg/mL 75 mg/mL 75 mg/mL
S1437 Tizanidine HCl 15 mg/mL 10 mg/mL <1 mg/mL
S3061 Epinephrine HCl 44 mg/mL 44 mg/mL 7 mg/mL
S3060 Medetomidine HCl 47 mg/mL 12 mg/mL 47 mg/mL
S2523 DL-Adrenaline <1 mg/mL 0.02 mg/mL <1 mg/mL
S2615 Noradrenaline bitartrate monohydrate 64 mg/mL 64 mg/mL <1 mg/mL
S4127 Terbutaline Sulfate 100 mg/mL <1 mg/mL <1 mg/mL
S2576 Xylometazoline HCl 56 mg/mL 27 mg/mL 56 mg/mL
S4135 Clorprenaline HCl 50 mg/mL 50 mg/mL 50 mg/mL
S2373 Yohimbine HCl <1 mg/mL 12 mg/mL <1 mg/mL
S2362 Synephrine <1 mg/mL 33 mg/mL 2 mg/mL
S4266 Brimonidine Tartrate 75 mg/mL 88 mg/mL <1 mg/mL
S1642 Methyldopa <1 mg/mL 2 mg/mL <1 mg/mL
S2086 Ivabradine HCl 82 mg/mL 101 mg/mL 101 mg/mL
S2113 Cisatracurium Besylate 47 mg/mL 249 mg/mL 249 mg/mL
S3185 Adrenalone HCl 44 mg/mL 44 mg/mL <1 mg/mL
S2091 Betaxolol 62 mg/mL 62 mg/mL <1 mg/mL
S4043 Tetrahydrozoline HCl 47 mg/mL 12 mg/mL 26 mg/mL
S4100 Esmolol HCl 66 mg/mL 66 mg/mL 66 mg/mL
S4124 Tolazoline HCl 39 mg/mL 39 mg/mL 39 mg/mL
S2545 Scopine <1 mg/mL 31 mg/mL <1 mg/mL
S4278 Carteolol HCl 65 mg/mL 65 mg/mL <1 mg/mL
S4277 Bambuterol HCl 72 mg/mL 80 mg/mL 28 mg/mL
S4291 Labetalol HCl 8 mg/mL 72 mg/mL 7 mg/mL
S4296 Salmeterol Xinafoate <1 mg/mL 100 mg/mL 4 mg/mL
S4085 Levobetaxolol HCl 69 mg/mL 69 mg/mL 69 mg/mL
Tags: adrenergic receptor activation | adrenergic receptor types | adrenergic receptor location | adrenergic receptor drugs | adrenergic receptor signaling | adrenergic receptor pathway | beta adrenergic receptor pathway | beta adrenergic receptor activation | beta 2 adrenergic receptor activation | beta 2 adrenergic receptor pathway | alpha adrenergic receptor pathway | alpha 1 adrenergic receptor pathway | beta 1 adrenergic receptor pathway | adrenergic receptor inhibitor review
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